Posted by admin on Apr 30, 2021 in |
Tuberculosis (TB) is one of the top ten causes of death worldwide. Presently, one-quarter of the world’s population is thought to be infected with TB. New infections occur in about 1% of the population each year. Tuberculosis is a major global health threat. There is a progressive increase in multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR). Multi drug resistance (MDR)-TB and Extensively drug resistance (XDR)-TB poses a vital challenge to the control of tuberculosis. Numbers of drugs are available in the market for the treatments of tuberculosis as well as many new drugs are also available for the treatment of MDR-TB and XDR-TB. This review article covers most of the different official and reported analytical methods for the estimation of the first line, second line oral, and newer anti-TB drugs. The main objective of this review is to classify, summarize, and discusses the different proposed analytical methods for the estimation of above mentioned anti-TB drugs alone and in combination with other drugs in bulk, pharmaceutical formulation and biological...
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Posted by admin on Apr 30, 2021 in |
Pharmaceutical chemistry is devoted to the discovery and development of new agents for treating diseases. Inorganic compound continues to be important in therapy, for example, as antacids, mineral supplements, and radiopharmaceuticals, but organic molecules with increasingly specific pharma-cological activities are clearly dominant. The five and six-membered heterocyclic nitrogen-containing systems such as pyrazole, imidazole, trizoles, thiozolidine, pyrazolidine, etc., are far by the most important in the ongoing research for more efficacious drugs in the fields such as anti-bacterial, fungicidal, anti-inflammatory, anticonvulsant, diuretics, and anti-histaminic, etc. Pyrazoline is a five-membered heterocyclic compound having two adjacent nitrogen atoms within the ring. It has only one endocyclic double bond and is basic in nature. Pyrazole derivatives have a long history of application in agrochemicals and pharmaceutical industry as herbicides and active pharmaceuticals. The recent success of pyrazole COX-2 inhibitors has further highlighted the importance of these heterocyclic rings in medicinal chemistry. Many scientists have synthesized novel pyrazoline derivatives. They have characterized the synthesized compounds by thin-layer chromatographic technique and analyzed the spectrum by...
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Posted by admin on Apr 30, 2021 in |
Nano robotics is an emerging, advanced and multidisciplinary field that calls for scientific and technical expertise of medical, pharmaceutical, bio-medical, engineering as well as other applied and basic scientists. Nano robots differ from macro-world robots specifically in their Nano-sized constructs. Due to their small size and wide functional properties, nano robots have created exceptional prospects in medical, biomedical and pharmaceutical applications. Although, no technology is available to construct artificial nano robots, it is now possible to create nano robots by using biological means. Nanorobots, nano machines, and other nano systems are objects with overall dimensions at or below the micro meter range and are made of assemblies of nanoscale components with individual dimensions ranging approximately between 1 to 100 nm. Smaller the size, larger is the specific surface area and energy efficiency. This is the prime concept behind all micro or nanotechnology devices. Even though the nano robots have not yet been deployed in any commercial application with currently available science and technology, the ongoing intensity of research and...
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Posted by admin on Apr 30, 2021 in |
The present study reveals the importance of inclusion of knowledge regarding infectious diseases and their effect on the respiratory system in the school education system and in pharmacy courses. An integrative review of diseases that affect respiratory tract along with COVID 19. Family plays an important role to give protection from any kind of infectious diseases based on the achieved knowledge. Thus the education of consciousness in each and every family about the infectious diseases is very important, particularly mother and head of the family must be well equipped with the knowledge of infectious diseases including RTI etc. and then the only large population can fight against COVID 19 like pandemic with minimum mortality and fit society with the good financial system. To restructure the syllabus content in the school education system so that in each and every age, students are compulsory to be knocked about the infectious...
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Posted by admin on Apr 30, 2021 in |
In recent years, Plants and herbal drugs obtaining from natural resources are again gaining importance throughout the world in maintaining the healthcare conditions of individuals. The regular use of natural sources and plant-derived products throughout the world has increased serious concerns over their quality, safety, and efficacy. Adding to the natural scientific resources and knowledge, the tree Ailanthus excelsa Roxb commonly known as the tree of heaven, belongs to the family Simaroubaceae indigenous to central, south India, and Srilanka. The tree has several uses in medicine as the gum, and bitter, aromatic leaves and stem bark of the tree are reported to have medicinal properties. A variety of active compounds are obtained from the plant, which is used in combating a variety of human illnesses, and it also leads the path to search out new active natural and novel semi-synthetic or synthetic compounds. In the present review, we have tried to explore the latest scientific attributes along with traditional knowledge, therapeutic applications, and future prospects of Ailanthus excelsa...
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