Posted by admin on Jan 31, 2020 in |
Sufficient fluid solvency has been one in everything about required properties while choosing drug particles and completely uncommon bio-actives for advancement. Here and there dissolvability of a medication decides its pharmaceutical and remedial execution. Most of these days organized medicine IOTAS miss the mark or are rejected for the length of the main times of drug disclosure and improvement on account of the truth of their obliged dissolvability. Test consistency, liquid dissolvability, and manufactured equality of the prescription are central for touching base at enough bioavailability and supportive outcome. Dendrimers, an alternate class of polymers, have the decent potential for medication solvency improvement, by temperance of their unmistakable properties. These hyper-stretched, mono-scattered particles have the particular capacity to tie the medication atoms on fringe still to typify these particles among the fiber structure. There are differed reportable investigations that have effectively utilized dendrimers to flavor up the solubilization of inadequately solvent prescription. These promising results have intrigued the analysts to vogue, orchestrate, and evaluate fluctuated fiber polymers for his...
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Posted by admin on Jan 31, 2020 in |
Inflammation, a protective response, can be dangerous if left untreated. The current synthetic anti-inflammatory drugs available in the market are coupled with various side effects. Plant-derived products can serve as a better alternative being cheap, easily available and having very few side effects. A sizable number of plants having anti-inflammatory activity have been studied. The crude extract of the plant is easy to obtain but it is not possible to indicate the component responsible for a particular property of the extract as it is a mixture of various components. Therein lays the importance of isolating the active principles from the crude extract and studying their mechanism of action. The present study aspires to provide an insight into the current trend of treatment of inflammation using herbal remedies by highlighting the different active principles obtained from different parts of plants, their concentrations used in specific test systems alongside underlining their molecular mode of...
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Posted by admin on Jan 31, 2020 in |
Introduction: Benign prostatic hyperplasia (BPH) is a common age-related burden of males and found in more than 40% of men in their fifties. In Ayurveda, Vatasthila and Mutragranthi are condition mentioned under Mutraghata much resembles obstructive uropathy due to BPH. In modern medicine, management of benign prostatic hyperplasia (BPH) is either by surgical approach or by hormonal therapy and alpha-blocker etc. which has many complications. Thus, there is a need to update of herbal medications for treatment of BPH. The presented review article provides information on BPH and its treatment by herbal drugs. Materials and Methods: This review work was carried out by using a widespread and planned data mining approach through a search of the english-language literature indexed on Medline, Pubmed Central Journal Literature, scopus, web of science google scholar, science direct and the proceedings of scientific meetings. To achieve significant literature author uses the key words “herbal drugs in BPH”, “benign prostatic hyperplasia” “role of Ayurveda in BPH” and “current update for BPH Treatment. Results: nine publications...
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Posted by admin on Jan 31, 2020 in |
Blood transfusion is an important part of various treatment protocols. Blood should be transfused with certain precautions like drug because blood and its constituents have the propensity to cause effects like introduction of donor antigens within the recipient, transfusion reactions or exposure to numerous transfusion-transmitted diseases. Thereby, it is important for the clinicians to remember those potential risks to the recipient of blood and blood components as well as donors. Haemovigilance system includes monitoring, identification, reporting, investigation, and analysis of adverse reactions associated with transfusion. The data gained from the investigation and analysis facilitates corrective and preventive action to be taken to attenuate the potential risks related to safety and quality of blood donation and transfusion for donors and patients. Forever the developed countries have taken the lead within the haemovigilance. However, developing Asian countries like India lacks a well-established system for haemovigilance program. In this review we have compiled the various haemovigilance and blood safety studies conducted in India to know the current update of haemovigilance program in...
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Posted by admin on Jan 31, 2020 in |
In aerobic organisms, oxygen is essential for sufficient energy production but self-contradictory, produces chronic toxic stress in cells. So, protective techniques must exist for removal of toxic free radicals which are byproducts of oxygen. Diverse protective systems have evolved to enable adaptation of antioxidant activity. Tissues and organs have different rates of metabolic activity and oxygen consumption. Their levels of antioxidants are also different. Such is the case with glutathione (GSH) and cysteine, which are lower in the brain than the liver, kidney, or muscle. Investigations of oxidative responses in different complex organisms such as mammals, organs, and tissues which contain distinct antioxidant systems and this may form the basis for differential susceptibility to toxic agents. Notable advances have been made in our understanding of these distinct systems, with several antioxidant systems and their regulatory pathways being described at the cellular level, thus understanding the pathways leading to the induction of antioxidant responses will enable development of strategies to protect against oxidative...
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