Posted by admin on Jun 30, 2025 in |
Diabetes is a multifaceted metabolic disorder that impacts individuals worldwide, and delayed wound recovery is a prevalent symptom of diabetes. There is a plethora of methods available now to heal these wounds. Since, chronic inflammation and untreated stages may lead to amputation and death. So, their consequences may cause a patient’s financial strain. However, this review focuses on the most recent formulation, such as miRNA, biomarkers, exosomes, leucine-rich glycoprotein, neutrophils, pro-inflammatory (M1) macrophages, pro-remodeling (M2) macrophages, sustained activation of neutrophils, endothelial progenitor cells, Scaffold, biofilms, carriers, fibers, mats, and antibiotic management for diabetic wound treatment. We discussed their roles as well as therapy plans for managing diabetic wounds with the latest...
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Posted by admin on Jun 30, 2025 in |
Background: Intravascular lithotripsy (IVL) is an innovative method for treating heavily calcified coronary and peripheral lesions. It employs acoustic shock waves to create microfractures in calcified plaques, facilitating stent placement and improving vessel compliance. Objective: To assess the efficacy, safety, and potential applications of IVL in hypertensive patients with calcified coronary lesions, while exploring its diagnostic and therapeutic capabilities. Methods: A thorough review of the latest advancements and studies on IVL, with a focus on its use in hypertensive patients. Key studies, including the Disrupt CAD series, were analyzed for procedural success, safety, and clinical outcomes. The integration of IVL with imaging techniques such as intravascular ultrasound (IVUS) was also investigated. Results: IVL has shown high procedural success rates and minimal complications in treating calcified coronary and peripheral lesions. Studies have reported significant luminal gain post-IVL, with minimal residual stenosis. The Disrupt CAD studies confirmed the safety and efficacy of IVL, with minimal adverse events and substantial calcium fracture in treated lesions. IVL’s effectiveness in managing specific clinically significant...
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Posted by admin on Jun 30, 2025 in |
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age. It is characterized by symptoms such as elevated androgen levels, the presence of multiple cysts on the ovaries, irregular or absent ovulation and various metabolic disturbances. Women with PCOS commonly experience metabolic dysfunction, obesity and infertility. They also face a higher risk of pregnancy complications and long-term cardiovascular disease. About 75% of individuals with PCOS have Insulin Resistance (IR). IR can trigger symptoms of PCOS, but hyperandrogenemia related to PCOS can also worsen IR. This review aims to summarize the current treatment options for managing IR in PCOS and to prevent the long-term complications associated with it. Current treatment strategies include lifestyle modifications, which remain foundational for improving metabolic health, alongside pharmacological interventions such as Metformin, Thiazolidinediones, GLP-1 Receptor Agonists (GLP-1 RA) and SGLT-2 (Sodium Glucose Co-transport) inhibitors. These established therapies offer significant benefits in managing IR and associated symptoms. Additionally, Inositol has gained recognition for its role in supporting metabolic and reproductive outcomes. Emerging...
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Posted by admin on Jun 30, 2025 in |
CardioMEMS devices represent a significant advancement in heart failure management, offering continuous, real-time pulmonary artery pressure monitoring. This review explores the technological foundations, recent innovations, clinical applications, challenges, and future directions of CardioMEMS technology. Based on micro-electromechanical systems, these devices have undergone substantial improvements in miniaturization, sensor technology, and wireless communication. Advanced data analytics and reporting systems transform raw pressure data into actionable clinical insights, enabling the proactive management of heart failure. Clinical studies have demonstrated the efficacy of CardioMEMS in reducing heart failure hospitalizations and improving patient outcomes, leading to their increasing adoption in clinical practice. However, challenges remain, including cost considerations, data management complexities, and integration into existing healthcare systems. Future developments in CardioMEMS technology may include multi-parameter sensing, closed-loop systems, and integration with artificial intelligence and wearable devices. These advancements have the potential to further enhance the capabilities of CardioMEMS devices, potentially revolutionizing heart failure management and expanding into other areas of cardiovascular care. As the technology continues to evolve, ongoing research will be crucial to...
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Posted by admin on Jun 30, 2025 in |
Herbal tea has emerged as a key component in the development of functional foods, offering a wide range of health benefits and applications. This comprehensive review explores the role of herbal teas in promoting health and wellness, focusing on their rich content of bioactive compounds such as polyphenols, flavonoids, and antioxidants. These compounds contribute to various health-promoting properties, including anti-inflammatory, antimicrobial, and immune-boosting effects. The incorporation of herbal teas in functional foods enhances their nutritional value and provides therapeutic potential in managing chronic conditions like cardiovascular disease, diabetes, and digestive disorders. Additionally, herbal teas are applied in diverse food products, such as beverages, baked goods, and dietary supplements, where their flavor, aroma, and health-promoting properties are utilized. This review highlights the growing interest in herbal teas as functional ingredients and their promising role in improving overall well-being through dietary innovation. The review also addresses key considerations such as safety measures, quality control, and regulatory frameworks to ensure the effective use of herbal teas in functional food products. Additionally, it...
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