Posted by admin on Mar 31, 2019 in |
Traditional medicine is finding more significance and application today, particularly when we are facing difficulty in the management of numerous medical conditions. More effective and palatable drug dosage forms are needed in the modern era. The recent trend in traditional medicine dosage forms is to enhance the solubility, bioavailability, pharmacological activity, stability, reduce the toxicity and increase the compliance, etc. Oral dosage form which can address these factors are granules (effervescent and rapid release granules), tablets (fast dissolving and rapid disintegrating tablet), capsules, suspension, syrups, etc. and topical dosage form includes toothpaste, natural hair dye, face pack, hand wash, liniment spray and roll-on, gel, creams (emulsion), shampoo, etc. Contemporary, traditional pharmacies including several Ayurvedic pharmacies have already implemented these new trends and launched several new dosage forms apart from traditional under cover of conventional knowledge; few of such Unani products have also been launched. There is an immense need to adopt these recent trends in respect of the dosage form in Unani and another Indian traditional medicine pharmacy for...
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Posted by admin on Mar 31, 2019 in |
To develop a standard conventional solid dosage form like tablets it include the operations involving like milling, mixing, granulation, drying and compression which able to result in different qualities of the final products concerning the loading of the drug, the release of the drug, stability of the drug and pharmaceutical dosage form stability. To overcome some challenges of conventional pharmaceutical unit operations, 3DP is gaining more attention in the pharmaceutical formulation in the future. 3DP can successfully overcome the issues relating to the drug delivery of peptides, potent drugs, water-soluble drugs, and the release of multi-drugs, etc. The ideal opportunity of this technology is the preparation of personalized doses to state individual patient needs. This technology can be seen as the future of solid dosage forms produced on demand, with lower in cost and it also helps in minimizing side effects caused by excessive doses. However, some problems that limit the applications of 3DP in the commercial market, such as selections of binders which are suitable and excipients and...
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Posted by admin on Mar 31, 2019 in |
Background: Due to the rise of diabetes as the primary health issue nowadays, there is a need for a sweetener, which apart from fulfilling the role of a sweetener, also complies with the normal body metabolism. Objectives: To review the literature available on the different sugar alternates present globally. Methods: A literature search has been done on the various substitutes of sugar present, belonging to various categories such as artificial sweeteners, natural sweeteners, novel sweeteners, and sugar alcohols. Results: A vast variety of sugar substitutes are available, which are suitable in one or more ways. The main matter of concern is the selection of the right sweetener according to the requirement. Conclusion: Apart from being of low calorie, these sweeteners provide multiple advantages; therefore by choice of right alternate, consumers are benefitted with the sweet taste, thereby complying with the normal body...
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Posted by admin on Mar 31, 2019 in |
Herbal drugs play an important role in the treatment of much illness. The plant has tremendous biological effects and applied in the different system of traditional medication for the treatment of various diseases. Marsilea minuta is one of the most popular foreground plants for aquariums that grows about two to three inches tall in shallow water and has attractive little markings on the tiny, variegated, green leaves. It is an aquatic or sub-aquatic fern used as a vegetable, has wide applications in traditional/folk medicine in India and Bangladesh. It is a member of the fern family. Synonyms of Marsilea minuta are Marsilea crenulata Desv, Marsilea diffusa A. Braun and Marsilea rotundata Wild. Marsilea minuta possesses many pharmacological activities such as antipyretic and analgesic, antidiabetic, antitussive, expectorant, antiamnesic, anti-aggressive, antimicrobial, hepatoprotective, antifertility, anti-tumor, antioxidant activity. This study was aimed to present an overview of traditional use, phytochemical and pharmacological investigations present in this...
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Posted by admin on Mar 31, 2019 in |
Benzimidazole is a heterocyclic aromatic organic compound containing nitrogen. This bicyclic compound is formed by the fusion of benzene with imidazole ring. It is a vital Pharmacophore and privileged structure in medicinal chemistry which exhibits various therapeutic activities like antiulcer, antihypertensive, analgesic, antiviral, antifungal, anticancer and antihistaminic. The disease conditions targeted by these activities are discussed. The present article extensively covers various procedures of synthesis of 2-substituted benzimidazole and its analogs by utilizing different catalysts, solvent conditions, reactants and microwave irradiation with the aim to obtain an inexpensive, eco-friendly, less time-consuming procedure which ensures good yield and quick isolation of the pure product. Ongoing clinical trials of different benzimidazole derivatives exploring additional pharmacological activities are also...
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