Posted by admin on Jan 31, 2019 in |
Plants are an important source for the discovery of new products of medicinal value for drug development and plants secondary metabolites are unique sources for pharmaceuticals food additives, flavors, and other industrial values. The commercial importance of these secondary metabolites has resulted in a great interest in its production and in exploring possibilities of enhancing its production using tissue culture technology in recent years. A good number of abstracts and research articles published, so far, for evaluating antioxidant, the anti-microbial and anti-diabetic activity of different secondary metabolites which have been extracted from various plants. In this article, we reviewed bioactivity of flavonoids, alkaloids, and phytosterols of total 18 different plants. Out of which, total of 10 plants were found to show antioxidant potential, 9 plants were found to show anti-microbial potential, and 9 plants were found to show the anti-diabetic potential of secondary metabolites. Root, stem, leaves, fruits, and flowers of various plants were found to possess secondary metabolites to show bioactivity. So this article will be a comprehensive...
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Posted by admin on Dec 31, 2018 in |
The oral route is considered to be the most preferred route for administration of drugs for systemic effect, but the oral route is not suitable to the administration of drug for lower gastrointestinal (GI) diseases, this happened due to their release at upper GI tract (stomach, small intestine), which further minimizes the accessibility of drugs at the lower GI tract. To overcome this difficulty, colon-specific drug delivery systems have been broadly analyzed during the last two decades. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn’s disease, ulcerative colitis, etc. but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive drugs, and anti-diabetic agents. This review article discusses, in brief, the introduction of the colon, factor affecting the colonic transition, colonic diseases and the novel and emerging technologies for colon targeting....
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Posted by admin on Dec 31, 2018 in |
When a high amplitude nanosecond electric field applied to a biological cell it disrupts the equilibrium of the phospholipid bilayer resulting in the permeability of the cell membrane to increase. This results in movement of extracellular material into the cell which otherwise cannot move inside the cell. This phenomenon is known as electroporation. In the initial years of research people concentrated on to find out the process which leads to the above phenomenon, but till now it is not proved theoretically / mathematically the complete theoretical background about the process. In recent years with the help of new fundamental knowledge and the latest experimental electroporation researchers can shift the technologies based on electroporation for clinical validations. In this paper, we have discussed regarding the theories of electroporation and also regarding the usages of electroporation in medical technologies. We have also discussed the challenges to be faced and the research barriers to make this technology on the...
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Posted by admin on Dec 31, 2018 in |
Hydrotherapy or hydropathy is nothing but external or internal use of any form of water (i.e., water, ice, steam) for health promotion or treatment of various diseases with varying temperatures, pressure, duration, and site of application. It is one of the well known naturopathic treatments used widely in ancient cultures including India, Egypt, China, and other Asian countries. Many studies were conducted to understand the physiological and therapeutic effects of hydrotherapy on different organs, but the effect of hydrotherapy was not explored in many organs till. The main objective of this review is to report the scientific evidence-based effects of hydrotherapy on various physiological systems which are not reported yet. The review was conducted and found that hydropathy has therapeutic value and capacity to improve various physiological functions in some diseases and disorders. Diseases like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis required a long period of treatment to cure by using allopathic medicine, whereas using hydrotherapy can reduce the duration of treatment. Moreover, if the combination of both medication...
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Posted by admin on Dec 31, 2018 in |
Psoriasis a kind of skin condition which is said to be a type of autoimmune disease making the epidermal layer of skin to deteriorate and cause severe itching, form plaques, red scaling, papules. It can be due to the genetic predisposition as the affected genes get involved in the control of the immune system. Psoriasis generally doesn’t have a specific site, it occurs anywhere on the body including the scalp which results in the formation of plaques that causes excess scales, and its severity may result in loss of scalp hair. Scalp psoriasis tough to treat as the hair acts as a barrier for the application of topical medicines. In this article, we discuss the clinical characteristics, differential diagnosis, effects on quality of life, and the appropriate therapeutic approach for controlling scalp psoriasis. Since, the disease relevance is high and could lead to severe consequence, there is a need for the development of effective...
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