Posted by admin on Sep 30, 2018 in |
The aim of this review article is to reflect the current availed study on green synthesis of silver nanoparticle and its future prospects to treat chronic diseases. The development of eco-friendly and reliable techniques for synthesis of silver nanoparticles is a vital step in the area of nanotechnology. The researchers have shown more interest and attention on this because of its unique properties and applications in various fields such as medicine, catalysis, water treatment, nano electronics, pollution and textile field etc. This review is highlighting the advantages and benefits of green synthesis of silver nanoparticles over the other nanoparticles, using various plant extracts and it’s applications in a specific cancer disease treatment as well as in other diseases. Green synthesis of silver nanoparticles with controlled release, drug targeting, as well as significantly increase the bioavailability of drugs, which greatly overcome the weaknesses of traditional drug...
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Posted by admin on Sep 30, 2018 in |
The efficiency of drug discovery and designing process can be increased by effective strategies given by computational methods. Drug designing is an intense, time consuming and an interdisciplinary venture. Traditionally, drugs were discovered by synthesizing compounds in a long-drawn-out and multi-step process. Recent studies have shown an increase in day by day demand of novel and more efficient drugs. Due to availability of low-cost computer power, the use of such computers has become a leading topic in medicinal chemistry. In search of potent drugs computational techniques like docking, homology modelling, pharmaco-phore modelling, are employed by researchers around the globe in order to achieve the goal. The main purpose of this document is to give a summary of drug design process and specifically the role of computational modelling techniques. These involve some techniques from binding sites prediction to high throughput screening of large compound...
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Posted by admin on Sep 30, 2018 in |
Liver disease is the tenth most common cause of death in India as per the World Health Organization and may affect every one in Five Indians. In spite of consistent human effort and drug discovery, modern drug has very little to offer. Nonetheless, Ayurved classical proprietary and patented formulations have shown promising results. The present study provides a general review of the Ayurved products along with pharmacological actions of herbal medicines. Arogyavardhini vati, Liv 52 are the highest prescribing medicines in liver disorders. Curcuma longa, Phyllanthus niruri, Tephrosia purpurea, Picrorrhiza kurroa, Swertia chirayata are the commonest single herb used by the herbalist and Ayurved physician in the treatment of various liver disorders. An attempt has been made to compile classical, proprietary and patented Ayurved products. This may be useful to the clinicians, professionals, scientists and scholars working in the field of Ayurved for new product...
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Posted by admin on Sep 30, 2018 in |
Papaya (Carica papaya Linn.) is well known for its nutritional as well as medicinal value since long time. The medicinal properties of fruit and other parts of papaya are well known in the different system of traditional medicine including Ayurveda. Its various parts has been reported for various disease conditions viz. fever, swellings, jaundice, gonorrhea, bilious fever, itches, eczema, and rheumatism cold, headache, whooping cough, asthma, chicken pox, and bronchitis in various traditional literature. The various remarkable researches on biological activities and medicinal application have been reported during past four decades and established it as an important nutraceuticals agent. Carica papaya Linn. leaf has been scientifically studied for various therapeutic activities like antibacterial, antioxidant, antipyretic, insecticidal, antimicrobial, anti-molluscal etc. In view of this leaves have been explored through several advanced techniques like phyto-extraction of heavy metals, phytoremediation of particulate pollution and many others. Various studies on phytoconstituents and chemical composition of leaves have been reported in last few decades. The present review aims an exploration of pharmacognostical, phytochemical and...
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Posted by admin on Aug 31, 2018 in |
Medicinal plants and natural products have many applications in the treatment of viral diseases, due to much lower side effects. Different types of hepatitis, especially hepatitis B, are of the viral diseases whose treatment using herbal medicines is currently of great interest due to the limited availability of effective chemical drugs and having numerous side effects. Due to the attention paid to herbal drugs and their importance for the treatment of hepatitis B, we conducted this review to take a look at the evidence regarding the action mechanisms of viruses, antiviral herbal remedies and various herbal anti-hepatitis drugs and their therapeutic mechanism published until 2017. To provide data for conducting this review, the most up-to-date electronic journals including those indexed in the Pubmed, Elsevier, Institute for Scientific Information, Google Scholar and Scientific Information Database databases and various books, has been used. There are several plants for the treatment of viral diseases, including hepatitis B, which prevent or decrease infection via various mechanisms. Medicinal plants counteract viruses by various mechanisms,...
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