Posted by admin on Oct 31, 2017 in |
Lagerstroemia speciosa is commonly known as crape myrtle belonging to the Lythraceae family. Lagerstroemia speciosa or Banaba is a medicinal tree traditionally used to lower blood sugar in the body. Its high content of corosolic acid makes it an effective anti-diabetic drug. Banaba is also recommended for kidney, bladder problems and hypertension. Leaves of the species have been traditionally used over thousands of years as folkloric treatment by the native Indians and Japanese for illness, ailments particularly for lowering blood sugar levels and weight loss. The flower extracts of the species has some pharmacological properties like antioxidant and anti-microbial activities, whereas fruit extracts reported anti-nociceptive, anti-diarrhea and cytotoxic activities. Research on leaf extracts reveals that anti-bacterial, anti-viral, anti-inflammatory, anti-obesity, anti-fibrotic, anti-diabetic and xanthine oxidase inhibition, diuretic, decongestant activities and roots are applied for treating mouth ulcers. In addition to that bark is used to relieve the abdominal pains. The species also has essential metals like sodium, potassium, iron, zinc and magnesium which were clinically proved. Thus these reviews will...
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Posted by admin on Oct 31, 2017 in |
Swarna has been used all through these ages in various forms such as raw gold, pure metal, gold foils, red colloidal solution, Swarna Patra, Swarna Parpati and bhasma and other forms in varying dose and stands time tested. The procedure in which Swarna along with herbs are taken in the form of liquid, semi-solid or paste form by children orally is referred as Swarnaprashana. Swarnamritaprashana is formulated by modifying Swarnaprashana with scientific inputs and references from Ayurvedic classical literatures. Guduchi (Tinospora cordifolia (Thunb.) Miers), Brahmi (Bacopa monnieri(L.) “Vacha” Pennell), (Acorus calamus L.), Jatamamsi (Nardostachys jatamansi (D. Don) DC.), Ashwagandha (Withania somnifera (L.) Dunal), Shankhapuspi (Convolvulous pluricaulis Choisy), Yastimadhu (Glycyrrhiza glabraL.), Pippali (Piper longum L.) and Maricha (Piper nigrum L.) are the constituents of Swarnamritaprashana. Since 2009 May, Swarnamritaprashana has been administered once in a month at 12 centers at the Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India as a public health initiative. The current paper details how Swarnaprashana has got transformed into the current form...
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Posted by admin on Oct 31, 2017 in |
Cancer is a deliberating disease affecting people worldwide. Treatment of cancer has become a number one priority among medical specialists and different modes of treatment are being pursued. Various factors are involved in the proliferation of cancer thereby complicating its treatment. Certain enzymes or protein products within the cell can be up-regulated or down-regulated as the cancer progresses inside the tissue. In order to treat cancer, enzymes which play a key role in the disease can be targeted. These enzymes include cysteine cathepsins and matrix metalloproteinases. Cysteine cathepsins are a group of enzymes that are involved in degradation of the surrounding cell environment of cancer cells. The surrounding healthy cells are thereby invaded and destroyed by cancer cells. Hence they cause localized spreading and growth of cancer cells. Matrix metalloproteinase are mainly involved in metastasis of these cancer cells. They help in angiogenesis surrounding the cancer tissue thus providing nutrition to cells and proliferation via the blood stream. Hence both enzymes has a vital role in proliferation of cancer...
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Posted by admin on Oct 31, 2017 in |
Now a day’s world health organisation encourage, recommends and promotes traditional, herbal remedies in health care science, because these drugs are easily available at low cost and are safe but herbal medicines are not a simple task since many factor influence biological efficacy and reproducible therapeutic effect. These day’s colonic diseases are commonly seen and needs lifelong medical attention. Because of safety, herbal medicines can play vital role in the treatment of colonic diseases. Various natural therapies, available for the treatment of colonic diseases like ulcerative colitis, Intestinal bowel syndrome, colon cancer, etc. It is possible to improve the effect of these herbal medicines by targeting to the colon. This article review a detailed study about various pharmaceutical approaches used for colon targeting such as tablet, capsules, micro-particles, micro-sponges, lyposomes, etc. with herbal drugs and their effects. Effects of different process and formulation parameters on colon targeted drug delivery system are also discussed in following...
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Posted by admin on Oct 31, 2017 in |
Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual dosage form is to be placed under the tongue and produce immediate systemic effect of enabling the drug absorbed directly through the mucosal lining of the mouth beneath the tongue which is very rich to vascular blood supply. Sublingual spray is useful when rapid onset of action is desired with better patient compliance than orally ingested tablets. In terms of permeability, the sublingual area is more permeable than the vocal area, and hence also than the palatal area. The sublingual spray is to be sprayed for faster onset of activity. The absorption of drugs through sublingual route is 3-10 times larger than that presented by oral route hence can be employed for emergency weather. As per formulation aspects, dose uniformity of sublingual film is a technical challenge. On the other hand, ease of administration is more in the case of spray as compared to film. The primary advantages of sublingual...
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