Posted by admin on Apr 30, 2017 in |
Varicose Veins can be explained as a disorder of the veins (especially of legs) wherein they get affected due to the backward flow and turbulence in the circulation of the blood. The veins get perverted, become enlarged due to a condition called edema. The disease also shows many associated symptoms which worsens the condition of the varicose veins. The present article deals with brief introduction regarding the etiopathogenesis of varicose veins, related causes and symptoms, the current surgical and non-surgical treatments, and the study of natural drugs which may be useful in curing the varicose veins. It indicates the benefits of the natural drugs over the complicated treatments. The natural treatments may prove to be more beneficial and cost effective than the other complex treatments such as surgeries, and laser treatments. The aim of writing this review is to evaluate the role of the herbal drugs for the treatment of varicose veins and the critical analysis of invasive surgeries and complex...
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Posted by admin on Apr 30, 2017 in |
Neonatal jaundice is one of the most common diseases among neonates that may cause irreparable complications such as kernicterus. This systematic review article was conducted to report and introduce medicinal plants that are used to treat neonatal jaundice in Iranian traditional medicine. To conduct this systematic review, the terms jaundice and icterus combined with the terms ethnobotanical, ethno-medicinal plants, ethnopharmacology, phytotherapy, and Iran were used to search for potentially relevant publications in Google Scholar, and Scientific databases ISI, PubMed, and Scopus. According to ethnobotanical evidence, six plant species from five families consisting of Cotoneaster discolour, Ziziphus jujube Miller, Hordeum vulgare L., Alhagi graecorum Boiss, Fumaria parviflora, and Chicorium intybus have been more frequently reported to be used to treat neonatal jaundice in Iran on which a number of studies have been conducted. However, a combination of two or more number of these plants has been reported to be used for treating neonatal jaundice. Although the plants and their compounds cause reduction in neonatal jaundice through different mechanisms of action,...
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Posted by admin on Apr 30, 2017 in |
Medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention of various ailments. Today large number of population suffers from kidney stone, gall stone and urinary calculi. Stone disease has gained increasing significance due to changes in living conditions i.e. industrialization and malnutrition. Changes in prevalence and incidence, the occurrence of stone types and stone location, and the manner of stone removal are explained. Medicinal plants are used from centuries due to its safety, efficacy, cultural acceptability and lesser side effects as compared to synthetic drugs. The present article deals with measures to be adopted for the potential of medicinal plants in stone dissolving activity. The problem of urinary stones or calculi is a very ancient one and many remedies have been employed during the ages these stones are found in all parts of the urinary tract, the kidney, the ureters and the urinary bladder and may vary considerably in size. In the present...
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Posted by admin on Mar 31, 2017 in |
Resolvins and lipoxins endue a novel way of approaching aspirin mechanism of action by developing models. Recent advances in research of aspirin from starting point Willow bark (Salix alba) to resolvins and lipoxins along with their repurposing network. Therefore, aspirin have a big impact on most interesting areas of research. Aspirin and there interaction with several targets molecules (Magic shotguns) give the option in the uses of various disorder but there MOA based uses in all cases not limited to COX rather than newer ones like resolvins, lipoxins, protectins and maresins, In particular, resolvin and lipoxins will play a central part while research aspirin and their rescheduling in different human diseases that’s are better emphasize by novel MOA of...
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Posted by admin on Mar 31, 2017 in |
The regulatory expectations are changing day by day on the cleaning validation in Pharmaceutical industries, considering the patient safety and drug efficacy. Manufacturing of an Intermediate and Active Ingredient Pharmaceuticals involves many chemical syntheses and same equipment is being using for manufacturing of different product in multi-production facility. Equipment cleaning plays a key role in controlling the contamination, to control the potential carryover of the product, cleaning methods shall be designed effectively to reduce the previous product residue. The current good manufacturing practice regulations state that cleaning is a critical issue to ensure the product quality. Improper cleaning results the carryover of the previous product residue and leads to failure of the product, so adequate cleaning procedures should be in place to clean the equipment to provide the documented evidence. The established cleaning procedures and cleaning methods shall be validated, life cycle approach is considered for the cleaning validation process. The article discussed about the outlines of the life cycle approach for the cleaning...
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