Posted by admin on May 31, 2016 in |
This review article investigates the prevalent existence of suicide along with its risk factors and contributing factors leading to the culmination of them all, in an attempt to look behind the black curtain. Suicide is the result of an unbalanced scale between the good and bad. Every year 300,000 teenagers attempt and succeed at suicide worldwide. A set of emotions and unpleasant thoughts develop in a person’s mind. The consequences of such ideas resulted in suicide becoming one of the leading causes of death in adolescents worldwide. Suicide is multi factorial in nature and is still under study, but this review explores mainly the etiological factors, including social, economical, psychological, biological and physical factors. Increasing the awareness campaign to educate people on suicide would return as a decreased suicidal number. It is our job as humans to help to decrease these heart shaking losses by suicide. This can be done through offering help and support, and seeking out professional help. This is an integral step toward the recovery of...
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Posted by admin on Apr 30, 2016 in |
Diabetes Mellitus (DM), a global health care problem has been a burden to the socioeconomic society. The increasing incidence highlights the need for innovative approaches for the prevention and management, despite availability of various therapies for managing disease and its complications. There are several factors that seem to play a role in development of DM including genetic, lifestyle, environmental and nutritional conditions. Amongst nutritional factors, Vitamin D is likely to have an important role either in glycemic control or in attenuating diabetic complications. Vitamin D, an excellent marker of ‘good’ health has role in varied functions. Many of the epidemiologic studies have shown that vitamin D deficiency is associated with increased risk of chronic diseases such as cancer, cardiovascular disease, type 2 diabetes, autoimmune diseases and multiple sclerosis. Calcitriol (Vitamin D3) has reported to alter glycemic control and with some evidences pointing to its role in development of DM. Many studies done in past could not give conclusive association, hence benefit of supplementation of Vitamin D in DM patients...
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Posted by admin on Apr 30, 2016 in |
The Genus Costus (Linn.) is an important medicinal plant belonging to the family Costaceae. The Genus as a whole is often called Spiral Ginger. The genus is represented by about 175 species distributed throughout the world. The aerial parts of the plant and the rhizomes are edible, the rhizome being good source of carbohydrate, starch, amylase, protein and lipid. Moreover the rhizome is an alternative source of diosgenin and generally used to control diabetes. Rhizome of Costus is also used for curing many other ailments. In Ayurveda, the rhizomes are ascribed to be astringent, acrid, cooling, aphrodisiac, purgative, anthelmintic, depurative and expectorant. The present study focuses on the nutritional and pharmacological importances of Costus...
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Posted by admin on Apr 30, 2016 in |
In last few decades, there has been a great progress in understanding the biochemical and cellular events of normal wound healing. Healing of wounds, either accidental or surgical interventions, involves complex activities of blood cells, tissues, soluble mediators, cytokines and several growth factors. This increased cellular activity of damaged tissue enhances metabolic demands and active drug therapy. The main objective of treating a wound is to either shorten the time required for healing process or to minimize the undue effects. Plants due to presence of various valuable active phytoconstituents have immense potential for management and treatment of wounds over the years. All the Traditional systems of medicine, Ayurveda, Siddha and Unani describe applications of drugs of plant, mineral and animal origin to treat and heal wounds. Herbal drugs induce healing and regeneration of lost tissue by number of mechanisms. Due to their traditional applicability, affordability and safety plants gained a reputed position in the world of wound management and repair but scientific evidence for their wound healing potentials are...
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Posted by admin on Apr 30, 2016 in |
Recently the synthesis of fused heterocyclic compounds seeks great attention of researches in the field of medicinal chemistry. Majority of the drug compounds contains heterocyclic ring in their structures and these heterocyclic skeleton contributes significantly in the biological profile of drug. The heterocyclic compound play significant role in synthetic chemistry and many heterocyclic derivatives have been successfully synthesized as potent drug molecule. Many researchers have focused on the synthesis of fused heterocyclic compounds considering the beneficial property of fused derivatives and some of the fused heterocyclic compounds were found to possess potent biological action such as; antibacterial, antiallergic, anti-inflammatory, antitumor and antiparkinsonism etc. The basis of synthesizing fused heterocyclic derivatives resides in the fact that combination of two molecules or incorporation of new molecule in previously bio-active compound may potentiate action of each other synergistically, sometimes fusion leads formation of derivatives with newer biological profile other than the combining structure. This review article covers the most active heterocyclic compounds which possess considerable biological...
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