Posted by admin on Nov 30, 2016 in |
Emulgel systems are currently of attention to the pharmaceutical scientists because of their substantial potential to act as drug delivery vehicle by incorporating a broad range of drug molecules. These are either emulsion of water in oil type or oil in water, which is gelled by mixing it with a gelling agent. Incorporation of emulsion into gel makes it a dual control release system & also increases its stability. Due to lack of insoluble excipients and excess oily bases, it demonstrates better drug release as compared to other topical drug delivery system. Due to nongreasy because of the presence of gel phase which favors good patient compliance. In order to understand the potential of emulgel as delivery vehicles, this review gives an overview of the ideal properties, formation, and characterization of emulgels. The use of emulgel -based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future...
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Posted by admin on Nov 30, 2016 in |
Salvia L., is one of the largest genera from Lamiaceae (Labiatae) family which comprises 900 species and is widely distributed in various regions of the world like in America, Europe, Asia. In this review article, the triterpenoid constituents were investigated from all of the Salvia plants to date are reported. About 214 triterpenoids of different classes were isolated and characterized from 113 species of salvia genus. So far the Salvia plants were investigated for their diterpenoids, phenolics and monoterpenes (volatile oils), especially for diterpenoids rather than for their triterpenoid constituents. However, during the isolation procedures of Salvia plant extracts, ursolic and oleanolic acids are common triterpenoid with other constituents isolated. Salvia, in Latin named “salvare”, which means “to heal” so by name its medicinal importance was understand, since from ancient times different salvia species were used to cure more than sixty different ailments ranging from aches to epilepsy, and mainly to treat colds, bronchitis, tuberculosis, hemorrhage, and menstrual disorders. Salvia L., is one of the largest genera from Lamiaceae...
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Posted by admin on Nov 30, 2016 in |
Excipients are important partner in formulation that decide dosage form as well as Pharmacokinetics and pharmacodynamics of medicament. In contemporary era, excipients are used from synthetic resources, causes unwanted effect in pharmaceutics and therapeutics. So industries are looking towards natural resources as it delivers safe, biodegradable, cost effective, biocompatible and inert excipient to pharmaceutical industries. Leading organizations like WHO (World Health Organization), ICH (International conference on harmonization), IPEC (International Pharmaceutical Excipient Council) are working together to sort out the complication arises due to synthetic excipient and thus they are showing their faith inside traditional wisdom. In Indian subcontinent, Ayurveda is known medical sciences since 1000 BC and its existence till 21st century create a charm in contemporary scholar with a hope-light that Ayurvedic pharmaceutical wisdom shows a path for unique management of natural excipients. Interestingly, excipients in Ayurveda not only as inert supplements but also take part in pharmacological action. Here author investigated the concept of use, related pharmacokinetics and pharmacodynamics of natural nurture in Ayurvedic dosage form and...
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Posted by admin on Nov 30, 2016 in |
Aim: The aim of this review is to provide a detailed documentation and main features such as prevalance, manifestations and management regarding Kawasaki syndrome. Background: Kawasaki Syndrome was first described by Dr Tomisaku Kawasaki in Japan in 1967, since then prevalence of Kawasaki syndrome is increasing in all countries as per the reports in journals. This is more prevalent in Asian pacific regions. Kawasaki Syndrome is the most common cause of acquired heart disease in the U.S. and Japan with a high endemic rate of 150 per 100,000 in children less than 5 years. Materials and methods: This is a review based article, thus information regarding the topic was collected from different journals like European journal of paediatrics, Indian paediatrics , AHA scientific council etc. Reason: The purpose of this review is to put forward a well explained article about Kawasaki...
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Posted by admin on Nov 30, 2016 in |
Buddleja asiatica commonly called as butterfly bush is a tender deciduous plant. It is endemic to Asia and found in most parts of India. Traditionally it is used in the treatment of many health disorders such as inflammation, rheumatism, skin disease, malaria etc. In view of pharmacological aspect, Buddleja asiatica is screened for antihepatotoxic, antibacterial, hypotensive, anticancer, antifungal, antimalarial and antioxidant activities. More than 80 compounds including phenyl propanoids, flavonoids, Phenyl ethanoid glycosides, phenylpropanoid esters, non-phenolic compounds, triterpene saponins, iridoid glucosides, benzoates, triterpenoids, monoterpenes, acetogenins, steroids, shikimates as well as other trace elements have been identified in the plant. The flower has a pleasant fragrance and contains many flavonoids including apigenin, acacetin-7-O-β-D-glucoside, diosmin, rutin etc. The lanceolate leaves are rich in essential oil with tridecane, β-caryophyllene oxide, anethole and phytol as major components. This review provides morphological, ethnomedical, pharmacological and phytochemical data of the plant Buddleja...
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