Posted by admin on Apr 30, 2016 in |
Nanoparticles have attracted the interest of many research groups and had been utilized in an increasing number of fields during the last decades. Various methods can be used to produce nanoparticles such as ionic gelation, solvent evaporation, microemulsion, emulsion cross linking and precipitation. This review covers the general description, preparation and the detailed description of crucial parameters involved in techniques designed to obtain the desired properties of...
Read More
Posted by admin on Apr 30, 2016 in |
Genome engineering field is a new revolution in biological research and to this new field several restriction endonucleases are available. Out of all these, based on easier construction, sensitivity and specificity Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) preferred by scientists for research and industrial purposes. However, off-target DNA cleavage causes limitation to researchers who are interested in using engineered nucleases in gene or cell therapy. To overcome this issue, there is a need to design gRNAs which will produce CRISPR/Cas products with high specificity. Till writing this manuscript, there is no compile details available on such bioinformatics tools. Therefore, in this review we are trying to provide platform of information for research scientist who are working on CRSPR-Cas technology so that they can use these online and offline tools to prevent CRISPR/Cas off-targeting in research and industrial field depending on the type of...
Read More
Posted by admin on Mar 31, 2016 in |
Conventional chemotherapy drugs show lack of specificity, including reduced activity on cancer treatment with higher toxicity to normal cells and develop resistance after prolonged period of administration. Recently, to nullify all adverse effects of cancer chemotherapy nanometer sized carriers came into role for total cure. The advanced research community is focused on smart drug delivery system owing to their vivid biomedical and pharmaceutical applications. This article will provide an in-depth discussion on development of smart nanosized carriers for tumors targeting and highlight important role of QDs in highly challenging area of...
Read More
Posted by admin on Mar 31, 2016 in |
Lab-on-a-chip (LOC), a scaled down microfluidic device for carrying out laboratory operations outside the scope of standard laboratories is a rather appealing development in the field of science and technology for the whole laboratory has been reduced to a small chip capable of carrying out various functions. Keeping to its word, micro, miniaturized volume samples and reagents has ebbed the time taken to analyze a reaction apart from the distinctive behaviour of liquids at the nano scale which has permitted substantial control of molecular interactions and concentrations. Also, amount of chemical waste and the cost of reagents has been minimised very drastically. This review article thus focuses on the importance of LOCs in the field of health care apart from its progress and incorporation in biotechnological researches over the past...
Read More
Posted by admin on Mar 31, 2016 in |
Kamdhenu or Indian cow (Bos indicus) is worshipped as sacred animal by Hindus. The reason for worshipping is the tremendous therapeutic values of cow derived products like cow milk, cow milk curd, cow butter (ghee), cow urine, cow dung and a combination formulation Panchgavya. The use of these products has been well defined in ancient Ayurvedic texts like Charak samhita, Shushruta samhita, Brahad-Wagbhatt etc. Cow ghee showed anticancer and hepatoprotective potential by altering the enzymatic activities whereas cow urine acts by an unknown mechanism. Analgesic activity is attributed to presence of steroidal moieties and volatile fatty components in it. Antioxidants isolated from cow urine are responsible for antidiabetic, immunomodulatory, antiepileptic, antibacterial, antifungal and antimicrobial activities. Cow ghee contains a number of saturated and unsaturated fatty acids that plays active roles in production of inflammatory mediators and wound healing processes. This study is to gather the scientific research findings to support the traditional uses of cow derived products and to create research interest in...
Read More
