Posted by admin on Sep 30, 2015 in |
Globally cancer is a disease which severely effects the human population. There is a constant demand for new therapies to treat and prevent this life-threatening disease. Scientific and research interest is drawing its attention towards naturally-derived compounds as they are considered to have less toxic side effects compared to current treatments such as chemotherapy. The Plant Kingdom produces naturally occurring secondary metabolites which are being investigated for their anticancer activities leading to the development of new clinical drugs. With the success of these compounds that have been developed into staple drugs for cancer treatment new technologies are emerging to develop the area further. New technologies include nanoparticles for nano-medicines which aim to enhance anticancer activities of plant-derived drugs by controlling the release of the compound and investigating new methods for administration. This review discusses the demand for naturally-derived compounds from medicinal plants and their properties which make them targets for potential anticancer...
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Posted by admin on Sep 30, 2015 in |
Ethosomes are phospholipid-based elastic vesicles which have a potential as novel topical and transdermal drug delivery systems. They are ethanolic phospholipids vesicles which can act as carriers for various medicaments. Ethosomes have gained importance in the area of research, because of their intensified skin permeation, better delivery of drug and increased drug entrapment efficiency. These systems are more efficient in delivering substances to the skin because of the presence of ethanol, which provides a net negative charge on the surface, which helps to avoid aggregation of vesicles due to electrostatic repulsion than either conventional liposomes or hydroalcoholic solutions in terms of quantity and depth. Ethosomes are simple to prepare and safe to use. This review attempts to compile the various aspects like mechanism of action, methods of preparation (Hot method, Cold Method, Dispersion method using rotary evaporator) ,advantages, limitations, characterization, applications in different conditions like Anti-inflammatory, Arthritis, Acne, Fungal infections, Bronchial asthma, chronic bronchitis, emphysema, Diabetic condition, Scleroderma, systemic lupus erythematosus and psoriasis, etc of reported ethosomal formulations for...
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Posted by admin on Aug 31, 2015 in |
Resveratrol, an antioxidant found in red wine and certain foods, has been touted as a natural way to slow aging and fight cancer, obesity, heart disease, and diabetes. It also could be accounted as an agent, which has effects to reduced risk of inflammation and blood clotting. In addition there are some studies showing that resveratrol may actually reduce the positive effect of exercise on the heart in older men, but it’s important to know that its effects only last a short time after drinking red wine. As promising as it sounds, it is not yet established how resveratrol affects humans, since most studies have been conducted on animals and microbes. Because the information on resveratrol, presented in literature, pointing its health and adverse effects is full with contradictions, especially with respect to the human response, we tried to present the available information with minimal commentary, remaining as neutral as possible and allowing the reader to draw its own conclusion on recommendation of the wide increase usage of resveratrol...
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Posted by admin on Aug 31, 2015 in |
Elytraria acaulis Lindau, Acanthaceae (Family), also known as the Asian scalystem places itself an important position in the history of Indian system of medicine. It is found throughout Nigeria, Angola,Ghana, Uganda, Kenya, Botswana, Malawi, Mozambique, Zambia, Zimbabwe, Tanzania, South Africa, Somalia and India. Indian ayurveda explored in treating several ailments by using natural products derived from the medicinal plants. Using synthetic drugs to cure many diseases are adversely affecting immune system of the body. E.acualis is extensively used in the treatment of diabetes, diarrhoea and worm infections. It exhibits anti inflammatory, anti oxidant, anti hyperglycemic and anti fertility activities. In olden days the roots were made into paste and were topically applied for the treatment of leucorrhoea, snake bite and piles. This present study depicts the phytochemical and the pharmacological profile of Elytraria acaulis...
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Posted by admin on Aug 31, 2015 in |
SLN is a challenging field of nanotechnology notified in the recent years. It has been proved that SLN is more beneficial colloidal drug delivery system because of its more controlled and targeted properties. Recent advances in nanotechnology has indicated unimaginable guarantee to adjust disease therapeutics by creating new treatment modalities which may permit better focused delivery of anticancer medications to destroy dangerous cells in different malignancies. Due to their unique size dependent properties, lipid nanoparticles offer possibility to develop new therapeutics. Parts of SLN stability and the influence of different excipients (utilized as a part of SLN creation) on stability with other optional steps included in their adjustment like freeze drying, spray drying and so on. Issues connected with SLN creation and instrumental strategies utilized as a part of generation are altogether talked about. This review discuses on many aspects of SLN such as its structure, aim, advantages disadvantages, method of sterilization, method of preparation, principle of drug release , route of administration and Its medicinal applications. Study of...
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