Posted by admin on Mar 31, 2025 in |
The combination of bioinformatics and AI improves the precision and productivity of medication development. Artificial intelligence (AI)-powered tools such as AlphaFold and Atomwise speed up the discovery process, and natural language processing (NLP) helps with literature mining and medication repurposing. Advanced approaches such as automated drug testing and quantum computing are also being studied. Despite challenges such as legal constraints and data quality difficulties, the report emphasizes the potential for these technologies to alter precision medicine in the future. This review looks at how bioinformatics and artificial intelligence are altering the pharmaceutical sector. Especially for complex diseases such as neurodegenerative disorders, conventional drug development approaches are costly, time-consuming, and yield low-quality results. AI methods such as machine learning (ML) and deep learning (DL) significantly speed up drug discovery by predicting drug-target interactions, optimizing drug design, and analyzing ADMET profiles. Meanwhile, bioinformatics facilitates the understanding of biological data by means of the analysis of proteomic, metabolomic, and genomic data. This allows greater...
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Posted by admin on Mar 31, 2025 in |
Recently care regarding functional finishing of medical apparels such as liquid/blood repellent and antimicrobial has increased due to the risk of harmful microbes generation on these fabrics while coming in contact with fluids such as blood, sebum etc. Of the various medical textiles, surgical apparels are important textile products as they protect health care workers from microbial contamination. As consumers have become more aware of hygiene and potentially harmful effects of microbes, the demand for antimicrobial finished clothing is increasing. Different chemicals and heavy metal finished fabrics even though provide good liquid/blood repellent and antimicrobial activity, but these compounds cannot be used for the development of surgical gown due to factors like toxicity and non-biodegradability. Over the last few years, several attempts have been made to replace petroleum products with renewable and biodegradable components. Hence, fabric finished with chitosan (natural polymer)-herbal bionanocomposite are considered significant for fulfilling these objectives. This review discusses different protective textiles prepared with different antimicrobial and liquid/blood repellent finish used in medical textiles. It also...
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Posted by admin on Mar 31, 2025 in |
Cardiovascular diseases (CVD) are the leading cause of mortality and morbidity globally, with 17.9 million deaths in 2019. In India, the CVD epidemic is characterized by rapid accumulation, early age of disease onset, and high case fatality rates. India experienced a 59% increase in premature mortality from 23.02 million in 1990 to 37. Million in 2010. Despite improvements in diagnosis and treatment, heart disease remains prevalent, with a 50% chance of developing it by age 45. The main causes of CVD are ischemic heart disease and stroke. India’s age-standardized CVD death rate is higher than the global average. Artificial intelligence can enhance the identification and treatment of cardiovascular disease by improving quality control and enhancing medical professionals’ expertise. This technology can be used in standard clinical procedures, including nanotechnology-based interventions, risk factors determination, treatment regimens, and patient tracking for chronic cardiovascular diseases. This article highlights the global and Indian burden of cardiovascular diseases (CVD), with rising mortality and early disease onset. It emphasizes the need for improved diagnosis and...
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Posted by admin on Mar 31, 2025 in |
Diabetes mellitus is a chronic metabolic disorder characterized by high levels of glucose in blood due to non-secretion of insulin or insulin insensitivity. Diabetes mellitus can cause many complications, acute complications include non ketotic hyperosmolar coma and diabetic ketoacidosis. Different types of diabetes mellitus are available – Type 1 diabetes mellitus (hormone dependent diabetes) and Type 2 diabetes mellitus (non-insulin dependent polygenic disorder mellitus) are now recognized as serious global health problem, growing rapidly worldwide and taking its place one of the main theats to human health in the 21st century. In diabetes history gestational diabetes is the major and big problem, approximately 5 to 10 percent all pregnant women in the India is diagnosed as having gestational diabetes. The main indication of diabetes mellitus is a hyperglycemia in blood which due to in appropriate pancreatic insulin secretion or low insulin directed fostering to glucose by target cells. It is silent and affects millions of people in the world. It is estimated that in 2010 there was globally 300...
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Posted by admin on Mar 31, 2025 in |
The respiratory drug delivery system (RDDS), which delivers drugs straight to the lungs for quicker effect and better bioavailability, is essential for treating respiratory disorders. It works particularly well for treating lung infections, COPD, and asthma. Metered-dose inhalers (MDIs), dry powder inhalers (DPIs), nebulizers, and sophisticated aerosol formulations are examples of technology that are part of RDDS and maximize medication delivery to the lungs. Particle size, the drug’s physicochemical characteristics, and patterns of deposition within the respiratory system are some of the variables that affect how effective RDDS is. For example, smaller particles enhance therapeutic benefits by reaching deeper parts of the lungs. To ensure effective medication deposition while reducing adverse effects, the delivery system’s composition and design are essential. New developments in formulation science, nanotechnology, and inhaler design have propelled recent advances in RDDS. By improving treatment’s portability, accuracy, and convenience, these advancements are increasing patient adherence. Modern inhalers, for instance, provide improved particle accuracy and dosage control, increasing the treatment’s total efficacy. With its potential to revolutionize...
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