Posted by admin on Apr 1, 2014 in |
An immunomodulator can be defined as a substance, which can influence any constituent or function of the immune system in a specific or nonspecific manner including both innate or adaptive arms of the immune response. The Ayurvedic system of medicine details the concept of immunomodulation by the term Rasayana. The use of herbs for improving the overall resistance of body against common infections and pathogens has been a guiding principle of Ayurveda. Such herbs possessing immunomodulatory effects are referred to as Rasayana in Ayurvedic classics. Prakara Yoga is a chapter in one of the prime traditional Ayurvedic pediatric text book – Arogyakalpadruma. The whole content of Prakara Yoga chapter deals with different immunomodulatory recipes and procedures to be adopted right from the day after delivery. This paper is a review on the various concepts of immunomodulation detailed in the very same book along with the pharmacological studies conducted so far in this...
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Posted by admin on Apr 1, 2014 in |
Essential oils are a diverse group of natural products. Oils are the important source of aromatic and flavoring chemicals in food, industrial, and pharmaceutical products. Essential oil is a concentrated hydrophobic liquid containing volatile aroma compounds derived from the different parts of the plants. Various extraction methods are used in the manufacture and extraction of essential oils from the plant materials. Essential oils are produced using several techniques like water distillation, steam distillation, hydro diffusion, maceration, solvent-free microwave extraction, solar distillation and CO2 supercritical fluid extraction, etc. These extraction and expression methods are used to remove the oils from the dried/fresh plants (or) machines to squeeze the oil out of the plants. Out of all the extraction methods, supercritical carbon dioxide method is more efficient. The present paper is an attempt to list out the various methods of extraction of essential oil from the different parts of the plants and their merits and...
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Posted by admin on Apr 1, 2014 in |
Oral route has been the most convenient and accepted route of drug delivery. Owing to tremendous curative benefits of the oral controlled release dosage forms are being preferred as the interesting topic in pharmaceutical field to achieved improved therapeutics advantages. Gastroretentive drug delivery system is novel drug delivery systems which has an upper hand owing to its ability of prolonged retaining ability in the stomach and thereby increase gastric residence time of drugs and also improves bioavailability of drugs. Attempt has been made to summarize important factors controlling gastroretentive drug delivery systems. This review covers the advantages, disadvantages, marketed preparation and some patents of gastroretentive drug delivery system and represents the floating and non-floating gastroretentive system and also highlights some of the current gastroretentive approaches. Recent approaches to increase the gastric residence time of drug delivery systems include bioadhesive systems, floating systems (low density systems), non-floating systems (high density systems) , magnetic systems, swelling systems, unfoldable and expandable systems, raft forming systems and superporous systems, biodegradable hydrogel...
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Posted by admin on Apr 1, 2014 in |
Ayurveda, an ancient system of medicine explains well about joint disorders like vatarakta, sandhivata, amavata etc. Among these, amavata is a disease which is caused due to hypo-functioning of digestive fire. Rheumatoid arthritis is the disease which keeps clinical similarity with amavata. Ama is main pathogenic factor in the disease amavata. Factors causing formation of ama have direct impact on gastro-intestinal system. So, GI regulation is the mainstay of Ayurvedic therapy in amavata (RA).There are mental factors too which cause formation of ama & hence the disease. Modern system of medicine uses anti-inflammatories, DMARDs, immuno-suppressive agents. But these drugs have bad impact on the quality of life & have so many side effects. In Ayurveda, there are pharmacological and bio-purificatory measures which remove the toxins (ama) from the body without any side effect. Among pharmaco-therapy there are herbal, herbo-mineral preparations & various decoctions. Ayurveda also emphasizes on healthy life style and dietary behaviour to check the pathogenesis of the disease. There are researches which prove, that an Ayurvedic line...
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Posted by admin on Apr 1, 2014 in |
The traditional Indian system of medicine (Ayurveda) describes different modalities involved in the prevention and treatment of disease and stresses upon the role of diet, life style and drugs as cornerstones of therapy. Medicinal plant products are known to modify different aspects of human physiology and exert an alleviating influence on several pathophysiological states, and concepts of immunity and immune-modulation can be traced back several hundred years to the history of medicine. However, it is only in recent years that the scientific concept of immune modulation has been forwarded, and it now appears that some of the beneficial effects of Indian medicinal plants, proposed in Ayurveda by Charaka and Sushruta Samhita, may be due to these “immunomodulatory” effects. Several research groups have worked on the scientific basis of such immunomodulatory effects of plant products, and as a result, considerable data has accrued. The present review summarizes some of these experimental data in an attempt to justify some of their beneficial effects in health and disease, and also to provide...
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