Posted by admin on Feb 28, 2025 in |
Schedule M is considered as an important part in the Drugs and Cosmetics Act 1940, Rules 1945. For making a product with proper quality and effective for the human beings it is necessary to maintain or follow the guidelines of schedule M. Schedule M is considered as the guidelines which talks mostly about Good Manufacturing Practices. Schedule M was first established in the year 2001 and it was divided into Part 1 and Part 2. Then in the year 2018 it was divided into 12 Parts more precisely than first one which was established in the year 2001. Then in the year of 2024 it became more precise, and it was divided into 13 Parts and including the changes introduced in, the revised Schedule M which include introduction of a Pharmaceutical Quality System (PQS), Quality Risk Management (QRM), Product Quality Review (PQR), Qualification and Validation of Equipment, and a Computerized Storage system for all drug products. These revised Schedule M will help in making the product proper and effective...
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Posted by admin on Feb 28, 2025 in |
Acne vulgaris is a common chronic inflammatory skin disease found predominantly in adolescents in both sexes. The best acne treatment inhibits bacterial growth, encourages the shedding to the skin cells to unclog pores. Treatment for acne includes topical agents and systemic agents. Its quality monitoring becomes essential for assuring quality products for human care. So, for that purpose a detailed study of review was done including reported and validated methods, official monograph methods for estimation of Nadifloxacin and Adapalene. It was found from a literature survey that among all reported evaluation methods the most widely and predominantly followed method is HPLC. Other methods reported were UV, HPTLC. A conclusion was made that there is lack of evaluation analytical methods for simultaneous estimation of Nadifloxacin and Adapalene in combined dosage...
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Posted by admin on Feb 28, 2025 in |
Anethum graveolens (Dill) leaves and seeds of the plant are mainly used for traditional health treatments like diuretics and stomach disorders. Various observations of Anethum graveolens plant oil and other extracts showed antidepressant, analgesic, antiproliferative, antimicrobial, anti-inflammatory, analgesic, antioxidant activity, effects on gastrointestinal system, hyperlipidaemic effects, contraindications and adverse effects, and effects on reproductive system. Further, it is also used to prevent food spoilage or contamination. In the food industry, it is also used for flavoring foods. The important isolated molecules reported are carvone, dihydrocarvone, limonene, cymen, carvacrol, phellandrene, coumarins, flavonoids, phenolic acids, steroids, etc. The various traditional uses of the plant parts are stomachic and diuretic in Ayurvedic...
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Posted by admin on Feb 28, 2025 in |
Medicinal plants have been utilized to treat a wide range of illnesses throughout human history. Plants are able to produce a wide variety of secondary metabolites, which are chemical substances that assist them defend against predators. The plants are significant for their therapeutic significance because of these organic ingredients, which also have various biological actions. Red silk cotton tree, or Bombax ceiba L., is a member of the Bombacaceae family of plants. B. ceiba is a tall tree whose components are used to treat a variety of ailments. These parts include the flower, leaf, gum, fruits, seed, stem bark, roots, heartwood, and thorns. Essential phytoconstituents including lupeol, vanillin, anthocyanins, shamimin, and mangiferin are found in B. ceiba. The herb has been used therapeutically in Ayurvedic, Siddha, and Unani medicine, among other ancient medical systems. This page provides a thorough analysis of B. ceiba’s pharmacological, phytochemical, and therapeutic...
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Posted by admin on Feb 28, 2025 in |
Today, obesity has become a global pandemic affecting billions of people worldwide. It is associated with increased risks of various diseases, including cardiovascular and musculoskeletal diseases, psychiatric disorders, cancer, and diabetes, making it a significant public health issue. Obesity has also been linked to an elevated risk of metabolic diseases and changes in brain structure and function. The body mass index (BMI) is widely used to determine excessive weight in relation to height and age. However, BMI may not be accurate for everyone, and BMI z-scores are employed when analyzing data on children and adolescents. The accumulation of excess body fat, which contributes to obesity, is attributed to an imbalance between energy intake and expenditure, controlled by the brain’s central nervous system. Disturbances in the brain circuits that regulate energy balance can impact body weight and adiposity, often involving changes in neurotransmission, which may be addressed with CNS-targeting drugs. The pathogenesis of obesity is characterized by a chronic energy imbalance between excessive calorie intake and inadequate calorie expenditure, primarily...
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