Posted by admin on Aug 31, 2024 in |
Artificial Intelligence (AI) focuses on producing intelligent modelling, which helps in imagining knowledge, cracking problems and decision-making. Recently, AI played an important role in various fields of pharmacy like drug discovery, drug delivery formulation development, poly-pharmacology, hospital pharmacy, etc. In drug discovery and drug delivery formulation development, various Artificial Neural Networks (ANNs) like Deep Neural Networks (DNNs) or Recurrent Neural Networks (RNNs) are being employed. Several implementations of drug discovery have currently been analysed and supported the power of the technology in quantitative structure-property relationship (QSPR) or quantitative structure-activity relationship (QSAR). In addition, de novo design promotes the invention of significantly newer drug molecules with regard to desired/optimal qualities. In the current review article, the uses of AI in pharmacy, especially in drug discovery, drug delivery formulation development, poly-pharmacology and hospital pharmacy are...
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Posted by admin on Jul 31, 2024 in |
One in every three people suffers from some kind of neurological disorder. Considering the huge burden of the disease, it is imperative to develop and treat such conditions. Because of time constraints and obstacles, treating neurological disorders remains challenging for medical professionals. The number of new pharmacologically active lipid compounds discovered using current drug development methods is steadily growing, but these compounds are water-insoluble. Having a drug for oral administration with optimal bioavailability was a huge risk. Epilepsy is a serious medical condition that requires immediate treatment. We need to make lipid-based formulations to improve their bioavailability. Surface tension-lowering agents can result in a water-insoluble formulation. Niosomes and nanoparticles will pass freely along the blood-brain barrier. The key goals in the development of nanomedicine are safety, high therapeutic effectiveness, drug targeting to specific locations to avoid off-target toxicity and increased pharmacokinetic behaviour through prolonged drug release with a significant safety margin. As a result, the highest clinical effectiveness can be reached by combining lipid and protein...
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Posted by admin on Jul 31, 2024 in |
The estimation of pharmaceutical and biological materials typically uses the key qualitative and quantitative technique known as high performance liquid chromatography (HPLC). It is the most adaptable, secure, trustworthy, and quick chromatographic approach for drug component quality control. Uterine fibroids are non-malignant developments that create in the uterus. They are otherwise called leiomyomas or myomas. Fibroids can be asymptomatic, however when they really do cause side effects, they can incorporate weighty feminine dying, longer or more continuous periods, pelvic strain or agony, successive pee or inconvenience peeing, developing stomach region, blockage, torment in the stomach region or lower back. This survey conveys a detail portrayal of logical ways were printed for the assessment of uterine fibroids drugs and its mix medication in prescribed drugs and natural frameworks. This evaluation incorporates scientific ways like high performance liquid chromatography (HPLC) study for the assessment of uterine fibroids drugs and with a blend combination. The purpose of this article is to evaluate the use of HPLC for chromatographic analysis of medications used...
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Posted by admin on Jul 31, 2024 in |
Attempts are made in understanding drug action and its molecular interaction with multiple target in living cell using computational power as a tool leading to the emergence of Network Pharmacology (NP) and Telemedicine (TM). Network Pharmacology (NP) has been appearing as an important tool in underlining the complex relationship between the pharmacokinetic and pharmacodynamics of drug, aids in the discovery of new drug targets and repurpose existing drug molecules. TM is utilization of communication as a tool to disseminate all types of Pathological and Pharmacological aid to the costumer. This new advancement has made it possible to cut down geographical barriers, need for travel, managing and improving disease treatment in remote and urban areas through teleconsultancy, teleradiology, telepathology and teledermatology. Network Pharmacology and Telemedicine not only opens up new therapeutic options but also aims in improving safety, efficacy of drugs along with effective diagnosis and treatment of diseases by creating awareness thus likely to become the core methodology of healthcare delivering in the future. This article highlights the applications...
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Posted by admin on Jul 31, 2024 in |
Chemotherapy is a familiar treatment technique that uses chemical drugs to kill cancer cells. This technique affects normal healthy tissues because it is unspecific and has toxic side effects. Now a days, nano technology application in chemotherapy have helped to solve uncontrolled problems of drug delivery and other side effects. Nanoparticles (NPs) can provide outstanding advantages over conventional drug delivery by having excellent properties such as controlled mode of action, different methods administration, and the ability to transport organic and inorganic molecules. Special ligands attached to polymeric NPs target the tumour site because of their chemical affinity to the malignant tissues. This article reviews the characterization, fabrication and application of NPs used in cancer chemotherapy. Moreover, different forms of polymeric chemotherapy was explored and analysed to better understand the effects of nano particles on cancer...
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