Posted by admin on Dec 31, 2024 in |
Grafting polymerization is a process in which polymer chains are covalently bonded (grafted) onto a backbone polymer, leading to the formation of a new material with enhanced properties or functionalities. This process involves the attachment of polymer chains (known as “graft chains” or “grafts”) onto the surface or within the bulk of the substrate material. Polysaccharides have numerous applications in various industries, including food, pharmaceuticals, cosmetics, and biotechnology. They are used as thickeners, stabilizers, emulsifiers, gelling agents, and drug delivery systems due to their biocompatibility, biodegradability, and functional properties. Flavonoids are a group of polyphenolic secondary metabolites found in plants, fruits, and vegetables. They show a wide range of health benefits. They have gained interest recently due to their possible benefits for human health, especially their antioxidant, antiviral, antiallergic, anti-inflammatory, and anticancer characteristics. Flavonoid-grafted polysaccharide-form complexes generate synergistic effects, such as enhanced physical, chemical, and functional properties. Therefore, they show great potential for applications in food, cosmetics, and medicine. Structural characterization methods of the graft products, including FTIR, NMR,...
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Posted by admin on Dec 31, 2024 in |
Lung cancer (LC) represents a significant global contributor to mortality, particularly for those between the ages of 40 and 50. Additional evidence for this predicament comes from the yearly rise in new LC cases and the disease’s dismal 5-year survival rate of fewer than 15%. Even though smoking has been linked to a significant portion of Lung Cancer cases, a sizable number of non-smokers also contract the condition, raising the possibility that LC development may have hereditary and epigenetic roots. The genome only has about 1% of coding regions. As a result, scientists have studied the genome’s noncoding region and discovered that noncoding RNAs are crucial to the etiology of lung cancer. In more detail, lncRNAs and miRNAs have been extensively investigated over several decades of research. The function of miRNAs in post-transcriptional gene regulation is widely known and understood. It has also been demonstrated that the antagonistic interaction between lncRNAs and miRNAs further regulates gene expression in both healthy and disease situations, including Lung Cancer. A circular RNAs...
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Posted by admin on Dec 31, 2024 in |
Concentrated preparations called extracts are made from raw materials by isolating specific components through specific methods. Essential oils, tinctures, liquid extracts, and dry extracts are among the different kinds of extracts. The type of input material, the solvent employed, the temperature, and the extraction time are all important variables. Efficiently isolating and condensing particular ingredients for use in tastes, perfumes, and medicinal applications is the aim of extraction. A Soxhlet system can be used to manufacture dill seed oil through continuous solvent extraction. The right solvent must be used for this procedure; ideally, it should be able to dissolve the targeted compounds without causing any degradation. In order to extract the oil, the Soxhlet extraction cycle involves heating the solvent, letting it evaporate and condense, and then repeatedly washing the raw material. Requirements for scaling up Soxhlet extraction include preserving steady-state mass and energy balances. While the energy balance takes into consideration the heat input and thermal losses during the process, the mass balance makes sure that the amounts...
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Posted by admin on Dec 31, 2024 in |
Skin fungal infections are a significant global public health concern due to growing resistance to traditional antifungal treatments. This study explores the fungicidal properties of key components in fish oils and their potential use in treating cutaneous fungal diseases. Fish oils contain bioactive substances like omega-3 fatty acids (EPA and DHA), vitamins, sterols, and antioxidants, which can combat fungal diseases by compromising cell membrane integrity, inhibiting fungal enzymes, influencing host immune responses, and interfering with fungal signaling pathways. Studies have shown that fish oil-derived chemicals are effective against fungal species linked to skin diseases, such as Candida spp., Malassezia spp., and dermatophytes. Preclinical investigations have shown that fish oil-derived molecules have medicinal potential. Topical formulations containing fish oil extracts have been shown to relieve fungal skin infections symptoms, facilitate healing, and have minimal negative effects. Combining fish oil with other natural antifungal substances, such as essential oils, plant extracts, and antimicrobial peptides, could create innovative treatment tactics for stubborn fungal infections, especially those produced by strains resistant to multiple...
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Posted by admin on Dec 31, 2024 in |
Despite being hard to define, stem cells have a lot of potential as therapeutic agents and as tools for understanding development. Like any new field, though, blind excitement can sometimes eclipse reality. Nine widespread misunderstandings that we feel have an impact on how we assess stem cells as therapeutic possibilities are outlined in this review. We propose that each of these factors should be carefully observed and taken into account when assessing a specific cell for use in therapy. The unquestionable promise of stem cell biology must be assessed using rigorous scientific techniques, and data from both positive and negative trials must be gathered and presented. Stem cell treatments are at show demonstrated for a run of clinical conditions past conventional beginnings to treat hereditary blood illnesses and have seen considerable victory. In this respect, developing utilize for stem cells is their potential to treat torment states and neurodegenerative infections such as Parkinson’s and Alzheimer’s malady. Stem cells offer trust in neurodegeneration to supplant neurons harmed amid certain infection...
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