Posted by admin on Apr 1, 2012 in |
Traditional use of herbal medicines implies substantial historical use and this is certainly true for many products that are available as ‘traditional herbal medicines”. In many developing countries, a large proportion of the population relies on traditional practitioners and their armamentarium of medicinal plants in order to meet health care needs. Today, the pharmacologically active ingredients of many Ayurvedic medicines are being identified and their usefulness in drug therapy being determined and high percentage of plants are used in traditional medicines. In the present article an attempt has been made on calamintha officinalis as a herbal option for different...
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Posted by admin on Apr 1, 2012 in |
The main objective of this review is to provide advance information for the drug discovery research from the divine herb Kalanchoe pinnata, which contains a wide range of active compounds, including alkaloids, triterpenes, glycosides, flavonoids, steroids, bufadienolides, lipids and organic acids. The pharmacological studies are reviewed and discussed, focussing on activities as immunomodulator, CNS depressant, analgesic, antimicrobial, anti-inflammatory, antiallergic, antianaphylactic, antileishmanial, antitumorous, antiulcerous, antibacterial, antifungal, antihistamine, antiviral, febrifuge, gastroprotective, immunosuppressive, insecticidal, muscle relaxant, sedative, anticancer. Now it becomes endangered plant which needs to be conserved as well as explored for its significant green...
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Posted by admin on Apr 1, 2012 in |
Solubility is an important parameter to achieve desired concentration of drug in systemic circulation for pharmacological response to be shown. Among all newly discovered chemical entities most of the drugs are lipophillic and fail to reach market due to their poor water solubility. The solubility behavior remains one of the most challenging aspect informational development. Hence various techniques are used for the improvement of solubility of poorly water soluble drugs which include micronization, chemical modification, pH adjustment, solid dispersion, complexation, co-solvency micellar solubilization, hydrotrophy etc. Of all these approaches solid dispersion have attracted tremendous interest as an efficient means of improving the dissolution rate and hence the bioavailability to arrange of hydrophobic drugs. This article reviews the various preparation techniques and types of solid dispersion based on molecular arrangement. Finally some of the practical aspects have also been considered for the preparation of...
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Posted by admin on Mar 1, 2012 in |
The plant kingdom plays a major role in the life of human beings and animals. A great deal of Pharmacological research has considerably improved the quality of herbal drugs in cancer treatment. Phytochemical tests in Pharmacognosy, structure elucidation in medicinal chemistry and various screening procedures in pharmacology helped to boost immune system in the body against cancer as breast cancer is the most serious problem in Oncology and fifth most leading cause of mortality in developed and also developing countries. Scientists have contributed number of years to investigate a remedy with no side effects and interested in finding a potent phytotherapeutic agent from herbs for this disease. They performed several research works by taking the active principles of many herbs and developed various herbal formulations which inhibit growth and spread of breast cancer on the metastatic phase stage IV. Some important ethanomedicinal plants (indigenous system of medicine) evidenced for breast cancer by scientific study have been discussed...
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Posted by admin on Mar 1, 2012 in |
Planterosomes, term “PLANTERO” means plant while “SOME” means cell-like. A novel emerging technique applied to phytopharmaceutical for the enhancement of bioavailability of herbal extract for medicinal applications. Since the two major limiting factors for molecules to pass the biological membrane for their absorption in the blood stream mainly includes lipid solubility and molecular sizes. There are many plant extracts having excellent bioactivity in vitro but low or less in vivo because of their poor lipid solubility and improper size of the molecule or both which result in poor absorption and bioavailability of constituents from plant extract and are destroyed in the gastric fluids when taken orally. Planterosomes are recent advanced forms of herbal formulations that have enhanced absorption rate, producing better bioavailability than conventional herbal extracts. Since they have improved pharmacological and pharmacokinetic parameters, they can be used in the treatment of the acute and chronic liver disease. Planterosomes are prepared by non conventional methods. Planterosomes absorption in GIT is greater resulting in increased plasma level than individual component....
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