Posted by admin on Aug 1, 2012 in |
Vitex negundo Linn. belong to family Verbenaceae. It is an important medicinal plant.Literaturesurvey of V. negundo revealed the presence of different classes of natural products including essential oil,triterpenes, diterpenes, sesquiterpenes, lignan, flavonoids,flavones glycosides, iridoid glycosides, and stilbene derivative. The plant is traditionally reported for its use for the treatment of cough, asthma, fever, eye disease, inflammation, intestinal worms, skin diseases, nervous disorders, leprosy and rheumatism. Roots are tonic, anodyne, febrifuge, bechic, expectorant and diuretic. This review is short review of last two years reporting the natural products isolated and biological potential of Vitex negundo...
Read More
Posted by admin on Aug 1, 2012 in |
From the dawn of civilization, medicinal plants are known to be part of human society to combat diseases. In recent times, focus on plant research has increased all over the world and various evidences have been collected to show immense potential of medicinal plants used in various traditional systems. India officially recognizes over 3000 plants for their medicinal value. It is generally estimated that over 6000 plants in India are in use in traditional, folk and herbal medicine. This paper aims to provide a comprehensive review on the phytochemical and pharmacological aspects of Curculigo orchioides, Amaryllidaceae also known as “Golden eye grass”. It possesses a vast ethnomedical history and represents a phytochemical reservoir of heuristic medicinal value. It is one of the oldest oriental medicines mentioned in Ayurveda as potential remedy for various ailments. The rhizome is rich in Curculigoside, other glycosides, steroids, flavonoids and also contains various polyphenolic compounds. Many pharmacological studies have demonstrated the ability of the rhizome shows antioxidant, anti inflammatory, spermatogenic, aphrodisiac, immunostimulant, hepatoprotective, antiasthamatic,...
Read More
Posted by admin on Aug 1, 2012 in |
Transdermal drug delivery system (TDDS) is topically administered dosage form in the form of patches which deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. By this constant concentration of drug remain in blood for long time. Polymer matrix, drug, permeation enhancers are the main components of TDDS; Polymers include gelatine, gum Arabic, methyl cellulose, starch, shellac, etc. (as a natural) to synthetic ones (polyethylene, polystyrene, acetyl co-polymer, polyvinyl chloride, polyamide, polyvinyl acetate, etc.) TDDS are of many types varying from single layer drug in adhesive to multi layer drug in adhesive and others are reservoir and the matrix systems. The market value of TDDS products are increasing with rapid rate, more than 35 products have now been approved for sale in US, and approximately 16 active ingredients are approved globally for use as a TDDS. Transdermal drug delivery is a recent technology which...
Read More
Posted by admin on Aug 1, 2012 in |
Peptic ulcer is a worldwide health problem because of its high morbidity, mortality and enormous financial implication. An estimated 15,000 deaths per year occur as a consequence of complicated PUD.A large number of drugs for peptic ulcer disease are available in mainstream medicine but they are associated with numerous side effects like arrhythmias, impotence, gynaecomastia and haematopoietic changes and the recurrence is also very common. In recent times, focus on plant research has increased all over the world and a large body of evidence has been collected to show immense potential of medicinal plants used in various traditional systems. Here, an attempt is made to summarise experimentally proved herbs used in PUD during last...
Read More
Posted by admin on Aug 1, 2012 in |
Modified Release (MR) Formulations have a modification in the release mechanism. Modified release dosage forms are developed by altering drug absorption or the site of drug release in order to achieve predetermined clinical objectives. Modified drug release from dosage forms is complemented by the allied processes of drug design, of dosage administration, and of membrane transport and absorption of drug to the biological site of action.Modified-release drugs have complex formulations that can offer an advantage over standard medication for some patients. Modified-release preparations should only be used where there is a clear clinical advantage over conventional-release preparations. In general, Modified-release preparations should be reserved for specific patients where there is a problem with compliance, effectiveness or side-effects which these preparations could help overcome. Modified–release technologies have become indispensable to resolving critical technical, therapeutic, and marketing challenges, such as improving patience compliance, less dosage timings, better safety, better indications, delivering poorly soluble and poorly absorbable API’s, product differentiation, patent protection, product life-cycle extension, and better margins. Modified-release formulation design can...
Read More
