Posted by admin on Jul 1, 2012 in |
Crinum is an important Amaryllidaceous plant thanks to the valuable biological and therapeutic activities of its chemical constituents, especially alkaloids. Many Crinum species have been commonly used in traditional medicines worldwide. Long ago, they have been subjected to extensive chemical, cytological and pharmacological investigations. Accordingly, this work comprehensively comprises both the alkaloidal and non-alkaloidal principles of Crinums isolated from 1950 and up to now, together with various biological and toxicological studies conducted on both the total extracts and individual compounds. As being a major common class of Crinum alkaloids, the current part of this review work highlights the lycorine-type alkaloids isolated so far from this plant in addition to their distribution in different Crinum...
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Posted by admin on Jul 1, 2012 in |
A supercritical fluid (SF) can be defined as a dense non condensable fluid. A fluid reaches the supercritical status when its temperature and pressure exceed the relevant critical temperature and pressure. At the critical point only a single phase exists which has some properties typical of liquids (density) and some of gases (viscosity, compressibility, and mass diffusion coefficient). For pharmaceutical applications, the most widely used SF is carbon dioxide (more than 98% of the applications have been developed using this fluid) because of its low and easily accessible critical temperature (31.2◦C) and pressure (7.4MPa), non-flammability, non-toxicity and inexpensiveness. The physical and thermal properties of SCFs fall between those of the pure liquid and gas. SCFs offer liquid-like densities, gas-like viscosities, gas-like compressibility properties and higher diffusivities than liquids. The properties of SCFs, such as polarity, viscosity, and diffusivity, can be altered several-fold by varying the operating temperature and/or pressure during the process. This flexibility is enabling the use of SCFs for various applications in the food and pharmaceutical industries,...
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Posted by admin on Jul 1, 2012 in |
This work has an innovative approach for the development of biological nanorobots with sensors for medicine. The biological nanorobots operate in a virtual environment based on random, thermal and chemical control techniques. The biological nanorobot architecture model has biological nano bioelectronics as the basis for manufacturing integrated system devices with embedded biological nano biosensors and actuators, which facilitates its application for medical target identification and drug delivery. The biological nanorobot interaction with the described workspace shows how these biological nanorobots detect the target area and supply the drug. Therefore, our work addresses the control and the architecture design for developing practical molecular machines. Advances in nanotechnology are enabling manufacturing nanosensors and actuators through nano bioelectronics and biologically inspired devices. Analysis of integrated system modeling is one important aspect for supporting nanotechnology in the fast development towards one of the most challenging new fields of science: molecular machines. The use of 3D simulation can provide interactive tools for addressing nanorobot choices on sensing, hardware architecture design, manufacturing approaches, and control...
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Posted by admin on Jul 1, 2012 in |
The use of herbal drugs for the prevention and treatment of various health ailments has been in practice from time immemorial. Acacia arabica has been reported to be effective against a variety of disease including diabetes, skin disease and most concerning with cancer. The fresh plants parts of Acacia arabica is considered as astringent, demulcent, aphrodisiac, anthelmintic, antimicrobial, antidiarrhoeal, with good nutritional value in Indian traditional medicine system. This article briefly reviews the ethanobotanical as well as medicinal uses of Acacia arabica with plant description. This is an attempt to compile and document information on different aspect of Acacia arabica and its potential use. More studies are needed before the pharmacological properties of Acacia arabica can be utilized in...
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Posted by admin on Jul 1, 2012 in |
Turmeric is an ancient spice derived from the rhizomes of Curcuma longa, which is a member of the ginger family (Zingiberaceae). Also known as ‘Golden Spice of India’ turmeric has been used in India for medicinal purposes for centuries. It has been used in traditional medicine as a household remedy for various diseases, including biliary disorders, anorexia, cough, diabetic wounds, hepatic disorders, rheumatism and sinusitis. In addition to its use as a spice and pigment, turmeric and its constituents mainly curcumin and essential oils shows a wide spectrum of biological actions. These include its anti-inflammatory, antioxidant, anti-carcinogenic, anti-mutagenic, anticoagulant, antifertility, anti-diabetic, antibacterial, antifungal, antiprotozoal, antiviral, anti-fibrotic, anti-venom, antiulcer, hypotensive and hypocholesteremic activities. Modern interest on turmeric started in 1970’s when researchers found that the herb may possess anti-inflammatory and antioxidant properties. Safety evaluation studies indicate that both turmeric and curcumin are well tolerated at a very high dose without any toxic effects. Thus, turmeric and its constituents have the potential for the development of modern medicine for the treatment...
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