Posted by admin on Aug 1, 2011 in |
In previous days, Column chromatography was used in many laboratories for preparative purposes as well as for reaction control in organic synthesis. Column chromatography is an extremely time consuming stage in any lab and can quickly become the bottleneck for any process lab. This leads to the development of novel preparative liquid chromatography in which mobile phase flows down by positive air pressure called as Flash chromatography. It is a simple, fast and economical approach to preparative Liquid chromatography .This review try to focus on principle, various components, general procedure, advantages and application of Flash...
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Posted by admin on Aug 1, 2011 in |
Mushrooms are an important natural source of food and medicines. Traditionally medicinal properties of mushroom have been well demonstrated particularly in Eastern Asian countries. In modern clinical practices, the bioactive compounds derived from the extract of mushroom sporocarps or mycelium has been widely used for the prevention and treatment of various human diseases such as cancer, diabetes, immune system disorders and infections. Recently, considerable attention is focused on anticarcinogenic bioactive compounds particularly those derived from medicinal or wild mushrooms. The present review analyses the potential therapeutic properties of medicinal mushroom Ganoderma lucidum and their applications in human health...
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Posted by admin on Aug 1, 2011 in |
Artemisinin and its derivatives have successfully been used in treatment of falciparum malaria infections in various parts of the world. More importantly, they have proved effective against strains resistant to conventional antimalarials such as chloroquine and mefloquine in those parts of the world where malaria is endemic. Only one clinically relevant artemisinin-resistant human malaria has been reported recently in South East Asia, although there are reports published on development of the rodent malaria parasite strains resistant to the drug earlier. This article reviews the implications of combination therapy on the pharmacokinetics and hence clinical efficacy of Artemisinins using relevant and published papers. It gives detailed account on the general chemistry and mechanism of action of the parent compound Artemisinin before considering its pharmacokinetics. Artemisinin-based combination treatments (ACTs) are now generally accepted as the best treatment options for uncomplicated falciparum malaria. They are rapidly and reliably effective. The article would focus on combination therapy & its implication on the pharmacokinetics & clinical efficacy of artemisinin & its derivatives and also...
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Posted by admin on Aug 1, 2011 in |
The objective of this review is to form a short compilation of phytochemical screening, pharmacological activity and some analytical methods available for Sapindus mukorossi plant. Although the plant is of importance in Ayurvedic system of medicine mainly as cleansing agent, a review article based on the phytochemical and pharmacological screening of Sapindus mukorossi is not so far reported. The main phytoconstituent isolated and identified from different parts of this plant are triterpenoidal saponins of oleanane, dammarane and tirucullane type. The structure and chemical name of the all the types of triterpenoidal saponins reported in Sapindus mukorossi is included in this review. Many research studies have been conducted to prove the plant’s potential as spermicidal, hepatoprotective, anti-inflammatory, anti-protozoal etc. This review focuses on the phytochemistry and pharmacological actions of Sapindus...
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Posted by admin on Aug 1, 2011 in |
Plants and there preparations have been used as medicine since ancient time. The Ayurveda and various ancient Indian literatures have evidence the use of plants for various disorders. Acalypha indica L is an erect annual herb with numerous long branches covered with soft hairs. According to the Siddha text, ‘Pathartha Guna Chinthamani’ (Page no: 179), Acalypha cures diseases of the teeth and gums, burns, toxins of Plant and mixed origin, stomach pain, diseases due to Pitha, bleeding piles, irritations, stabbing pain, wheezing, sinusitis and neutralizes predominance of the Kabha factor. In the traditional medicine the preparations from whole plants have been used to counter various diseases and disorders. The present review is therefore, an effort to give a detailed survey of the literature on its pharamacognosy, phytochemistry, pharmacological and traditional...
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