Posted by admin on Jun 1, 2011 in |
Kidney stone formation is a complex that results from a succession of several physicochemical events including supersaturation, nucleation, growth, aggregation and retention within the kidneys. Urinary stones affect 10-12 % of the population in industrialized countries. There are only a few geographical areas in which stone disease is rare e.g. Germany and in the coastal areas of Japan. So in the present review aims to give data highlighting the present trends in research of medicinal plants accredited with antiurolithiatic activity. This article may help investigators to identify lead compounds or herbal products responsible for urolithiatic activity....
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Posted by admin on Jun 1, 2011 in |
This paper focuses on a favor in order to examine the implications of patents on innovation in the view of biotechnological developments and the utilization and associated efficacy of present patent system in promoting biotechnological innovations and the related issues and challenges therein. This article deals with patent related area in field of biotechnology. It discusses the various issues in biotechnology...
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Posted by admin on Jun 1, 2011 in |
Oxygen is a necessary element that controls many metabolic reactions in human body. Increased amount of oxygen in the body leads to continuous chain of events resulting in the formation of deleterious toxic free radicals which are capable of quenching the macromolecules including proteins and nucleic acids. To counteract the toxicity of the free radicals, human body synthesizes both enzymatic and non-enzymatic antioxidants. Non-enzymatic antioxidants are small molecules, capable of preventing the oxidative damage incurred by free radicals. Antioxidants also play crucial role in the controlling the health problems such as heart diseases, cancer, aging etc. which occur mostly due to accumulation of free radicals. The present review focuses on the various roles of antioxidants in maintaining the human...
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Posted by admin on Jun 1, 2011 in |
Current modalities of diagnosis and treatment of various diseases, especially cancer have major limitations such as poor sensitivity or specificity and drug toxicities respectively. Newer and improved methods of cancer detection based on nanoparticles are being developed. They are used as contrast agents, fluorescent materials, molecular research tools and drugs with targeting antibodies. Paramagnetic nanoparticles, quantum dots, nanoshells and nanosomes are few of the nanoparticles used for diagnostic purposes. Drugs with high toxic potential like cancer chemotherapeutic drugs can be given with a better safety profile with the utility of nanotechnology. These can be made to act specifically at the target tissue by active as well as passive means. Other modalities of therapy such as heat induced ablation of cancer cells by nanoshells and gene therapy are also being developed. This review discusses the various platforms of nanotechnology being used in different aspects of medicine like diagnostics and therapeutics. The potential toxicities of the nanoparticles are also described in addition to hypothetical designs such as respirocytes and microbivores. The...
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Posted by admin on Jun 1, 2011 in |
The transdermal route of drug delivery has attracted researchers due to many biomedical advantages associated with it. However, excellent impervious nature of skin is the greatest challenge that has to be overcome for successfully delivering drug molecules to the systemic circulation by this route. This review describes enhancement techniques based on drug/vehicle optimization such as physical and chemical penetration enhancers. Various novel carriers and vehicles like micro/nano and multiple emulsion, Liposomes, Niosomes, and Transferosomes etc., along with formulation strategies has also been discussed in the present...
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