Posted by admin on Nov 30, 2024 in |
For the treatment of many illnesses and disorders, including gastrointestinal (GI) ailments, several medicinal plants have been used. Most children and adolescents often suffer from GI illnesses, which have overlapping clinical manifestations in diagnosis and treatment requirements. In order to address the symptoms of smooth muscle contraction and cramping in gastrointestinal illnesses as well as in other urgent clinical circumstances, medications having antispasmodic properties are typically used. The treatment of GI illnesses by antispasmodic herbs was a major component of alternative medicine. Due to the numerous nutritional and therapeutic advantages of these medicinal plants and the herbal products they produce, they are utilized from generation to generation. Due to the numerous nutritional and therapeutic advantages of these medicinal plants and the herbal products they produce, they are utilized from generation to generation. The existence of chemical components that are physiologically active may be the cause of the many uses. This review’s major objective is to concentrate on the therapeutic potential of plants with antispasmodic properties and their suggested mechanisms...
Read More
Posted by admin on Nov 30, 2024 in |
This comprehensive review investigates the evolution of patches and the transformative impact of smart patches on drug delivery. Beginning with a historical overview of patches, the review examines the advancements that led to the development of smart patches. It explores the design principles, functionalities and applications of smart patches in drug delivery, highlighting their potential to revolutionize medication administration and patient care. Additionally, challenges and future directions in the field are discussed, providing insights into the ongoing innovation and development of smart patch...
Read More
Posted by admin on Nov 30, 2024 in |
Nanotechnology is the idea of using medicines as a small machine inside the human body to detect and treat various diseases. Nanotechnology consists of deformation, separation, and consolidation of material from atoms and molecules due to its quick movement across the small capillaries. It allows immediate treatment to the targeted cells and also has fair use in oncology. Nanotechnology aims to reduce toxicity and side effects from healthy cells and increase the bioavailability and therapeutic effect in the targeted cells. But due to its ability to accumulate in body it can cause cell specific toxicity to overcome the challenge and create safe Nanoparticles green synthesis or preparation of Nanoparticles from biodegradable material like orange peel, eggshell etc are on trend. Nanoparticles based several vaccines also help us to combat global COVID-19 pandemic nanoparticle drug delivery are also becoming boon for some auto-immune diseases. This review describes the methods of preparation, characterization, classification, toxicity, and Nanoparticles...
Read More
Posted by admin on Oct 31, 2024 in |
There are a variety of treatment options for melanoma, but the high resistance of tumor cells to conventional therapies makes it necessary to develop new anticancer agents that will have decline toxic effects and greater effectiveness, thereby providing an incentive for the development of new treatments that can be used alone or in combination with other drugs. The flavonoids are phenolic phytoconstituents that have been shown to be efficacious in preventing a wide series of cancers, both in-vitro assays and in animal models, including in melanoma cells. Flavonoids, like naringenin, quercetin and apigenin, among others, have gained significant attention in recent years due to the fact that they possess a wide range of properties, including anti-inflammatory, antioxidant, and antiviral properties. However, its anti-carcinogenic effect, which affects the control of cell proliferation and cell-cycle sequence, induction of apoptosis, and suppression of tumor angiogenesis, may be the most significant. Although flavonoids have exhibited promising results both in-vitro as well as in-vivo, there are some concerns regarding their application to biological environments,...
Read More
Posted by admin on Oct 31, 2024 in |
This review paper compares medical device regulations across the United States (US), Canada, Europe, India, and Japan. It offers an understanding of the many regulatory frameworks that control the approval processes for medical devices, the Competent Authorities, the rules and regulations, the licensing or registration processes, the classification systems for devices, and the quality management/GMP standards. The US adheres to rigorous approval procedures, encompassing quality system regulations and stringent reporting standards. Health Canada’s regulatory system entails pre-market scrutiny, post-market surveillance, and compliance measures. India’s regulatory landscape requires urgent enhancements to streamline guidelines and implementation strategies. In the European Union (EU), products must meet essential conditions to obtain CE marking for market entry. Japan employs the PMDA & MHLW for safety reviews, approvals, and post-market monitoring. This comparative study underscores the importance of harmonizing global regulatory standards and highlights areas for future improvement. This study outlines key findings and implications, serving as a valuable resource for stakeholders navigating international medical device...
Read More
