Posted by admin on Apr 1, 2011 in |
Learning is the process of acquisition of information and skills, while subsequent retention of that information is called memory. Learning and memory together called as cognition. Also, memory is a process involving encoding, storing, and recalling information. Thus, memory records various facts and events, make it available for further use, and hence can be considered as most valuable health asset. To elucidate the biochemical and molecular mechanisms underlying learning and memory could be considered as one of the challenging tasks for neuroscientists. Poor memory, lower retention, and slow recall are common problems in today’s stressful and competitive world, especially with associated ageing process. Furthermore, the drugs currently available in market for the treatment of various learning and memory disorders are associated with several side effects indicating need of substitute medication from alternative system of medicine. On the other hand, several medicinal plants, designated as ‘‘Rasayan Drugs’’ in Ayurveda, are supposed to have specific influence on brain functions, and could be effectively used to treat such disorders without the associated...
Read More
Posted by admin on Apr 1, 2011 in |
The mainly deliberate endocrine product of the pineal gland, melatonin, has been reported to be involved in the feedback between neuroendocrine and immune functions and to exert oncostatic action, at least in certain experimental conditions. Melatonin seems to be a vital part of the immune system, by exerting direct and/or indirect stimulatory effects on both cellular and humoral immunity. Likewise, an antitumor activity of melatonin has been shown in several experimental models in vivo and in vitro. The means by which melatonin exerts its effects on immunity and neoplastic growth have not been elucidated. The different putative mechanisms of action of melatonin investigated so far are at this juncture briefly...
Read More
Posted by admin on Apr 1, 2011 in |
Pyrimidine nucleus is one of the most important heterocycles exhibiting remarkable pharmacological activities. The present review provides a broad view of the biological and medicinal activity possessed by compounds having pyrimidine...
Read More
Posted by admin on Apr 1, 2011 in |
It is well known fact that the right drug delivery system is critical to the success of a pharmaceutical product. A novel drug delivery system creates additional patient benefits that will add new competitive advantages for a drug and, thus, conserve or increase revenue. Chewing gum as drug delivery system holds tremendous potential not only in smoking cessation and oral health care arenas but also in other...
Read More
Posted by admin on Apr 1, 2011 in |
Transdermal drug delivery is proving to be superior to the conventional oral delivery of drugs owing to its distinct virtues. But it has got its own limitations as well- inability to transport large molecules, inability to overcome the barrier properties of stratum corneum and many more. Using this route of drug delivery along with novel approaches can help to solve these problems. Formulating the drug in a transfersome is one such approach. Transferosome is an ultradeformable vesicle, elastic in nature which can squeeze itself through a pore which is many times smaller than its size owing to its elasticity. Transferosomes are made up of a phospholipids component along with a surfactant mixture. The ratios of individual surfactants and total amount of surfactants control the flexibility of the vesicle. The uniqueness of this type of drug carrier system lies in the fact that it can accommodate hydrophilic, lipophilic as well as amphiphilic drugs. These drugs find place in different places in the elastic vesicle before they get delivered beneath the...
Read More
