Posted by admin on Aug 1, 2011 in |
In recent years scientific and technological advancements have been made in the research and development of oral drug delivery system. The reasons that the oral route achieved such popularity may be in part attributed to its ease of administration. Over the years, patient convenience and patient compliance-oriented research in the field of drug delivery has resulted in bringing out potential innovative drug delivery options. Out of which, medicated chewing gum (MCG) offers a highly convenient patient-compliant way of dosing medications, not only for special population groups with swallowing difficulties such as children and the elderly, but also for the general population, including the young generation. Today, medicated chewing gum meets the same high quality standards as...
Read More
Posted by admin on Aug 1, 2011 in |
A dendrimer is described as a macromolecule, which is characterized by its highly branched 3D structure that provides a high degree of surface functionality and versatility. The unique properties of dendrimers such as uniform size, high degree of branching, water solubility, multiagency, well-defined molecular weight and available internal cavities make them attractive for biological and drug-delivery applications. These artificial macromolecules may be synthesized to reach the size of nano objects having dimensions similar to proteins. Recently dendrimers have successfully proved themselves as promising nanocarriers for drug delivery because they can render drug molecules a greater water-solubility, bioavailability, and biocompatibility. These features have made their application in pharmaceutical, nanotechnology and medicinal chemistry particularly attractive. In addition Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) Uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimers. Commercialization of dendrimers is now forthcoming. The present review...
Read More
Posted by admin on Aug 1, 2011 in |
The nanoemulsion is one of the most efficient dispersed nanosystems of droplet size ranging to submicron size. Nanoemulsion are generally transparent or semi transparent system characterized by high stability. They are characterized by high stability. Submicron droplet size and high surfactant concentration makes it an efficient transdermal delivery vehicle. Research works proves that nanoemulsion is far more efficient drug delivery system than other transdermal drug delivery system. The efficacy of the nanoemulsion is enhanced by the nature and type of surfactant and co-surfactant used. Thus in this article ability of the nanoemulsion as a transdermal and topical delivery system is...
Read More
Posted by admin on Aug 1, 2011 in |
In previous days, Column chromatography was used in many laboratories for preparative purposes as well as for reaction control in organic synthesis. Column chromatography is an extremely time consuming stage in any lab and can quickly become the bottleneck for any process lab. This leads to the development of novel preparative liquid chromatography in which mobile phase flows down by positive air pressure called as Flash chromatography. It is a simple, fast and economical approach to preparative Liquid chromatography .This review try to focus on principle, various components, general procedure, advantages and application of Flash...
Read More
Posted by admin on Aug 1, 2011 in |
Mushrooms are an important natural source of food and medicines. Traditionally medicinal properties of mushroom have been well demonstrated particularly in Eastern Asian countries. In modern clinical practices, the bioactive compounds derived from the extract of mushroom sporocarps or mycelium has been widely used for the prevention and treatment of various human diseases such as cancer, diabetes, immune system disorders and infections. Recently, considerable attention is focused on anticarcinogenic bioactive compounds particularly those derived from medicinal or wild mushrooms. The present review analyses the potential therapeutic properties of medicinal mushroom Ganoderma lucidum and their applications in human health...
Read More
