Posted by admin on Nov 1, 2010 in |
In recent time, scientific investigations of medicinal plants using indigenous medical systems has attracted a lot of attention globally. Nature has bestowed our planet with an enormous wealth of medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention and cure of diseases and ailments. Inflammation is complex biological response of vascular tissue due to different harmful stimuli and pain is discomfort signals result of actual or potential injury to the body may associate with inflammation. Inflammation with pain is associated with different diseases like rheumatism, encephalitis, pneumonia, oesophagitis, cancer, heart problems, fibrosis etc. Nonsteroidal anti-inflammatory drugs and opioid analgesic are normally used in the treatment of inflammation and pain but can cause a lot of adverse effect. Therefore herbal drugs can be potential source to replace them. Every year a lot of plants form traditional medicinal system has been screened for their potential anti-inflammatory and analgesic activity but only few of them only...
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Posted by admin on Nov 1, 2010 in |
Pelletization methods like solution layering, suspension layering or powder layering and extrusion-spheronization process is the most frequently used method for producing spherical pellets which utilizes a granulating liquid such as water, requires drying steps which is time consuming. Many drugs exhibit stability problem due to the presence of water during processing and residual water during storage. In addition to that pellets produced by these techniques exhibit rapid drug release and require a film coating to provide controlled release properties. Hot melt extrusion and freeze pelletization technique is receiving a great deal of attention as alternative technique over other techniques which need water during processing and drying steps. This article reviews the recent finding in the preparation of pellets by these novel...
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Posted by admin on Nov 1, 2010 in |
Cancer is a genetic disease. The main causes of cancer are alterations of DNA, mutations, damage etc. Any herbs which may be a plant or a part of the plant that are used to maintain the health are called Herbal supplements or Phytomedicines. Plant extracts are generally prepared by boiling the herb in water. The goals of these herbal medicines include prevention and protection against cancer. The traditional plants like Eleutherococcus senticosis, Astralagaus membranaceous, and medicinal mushrooms are used in cancer treatment. The other herbs used in other parts of the world are Valeriana, Garlic, Curcumin etc. These herbal medicines along with benefits also include some adverse effects. This review summarizes the role of some pharmaceutically important herbal medicines used in treating...
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Posted by admin on Oct 1, 2010 in |
The Western Ghats of Kerala is famous for its medicinal plant wealth and the tradition of indigenous system of therapy, specifically the Ayurveda. Dasapushpam constitute a group of ten potential herbs which are culturally and medicinally significant to the people of Kerala in India. They are a group of ten herbs with which the ladies decorate their hairs and dance the Thiruvathira Kali on the day of Thiruvathira in the Malayalam month of Dhanu. These plants are therapeutically very active for various diseases and ailments. Many of them are traditionally used from time immemorial. Some of them are scientifically validated for various bioactivities. Still there are lots of possibilities for potential pharmacological activities from these herbs, yet to be explored. This article would give an insight of these ten sacred plants and their properties to further popularise these...
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Posted by admin on Oct 1, 2010 in |
The objective of the project is to develop a comprehensive database of Nuclear Receptor (NR) Superfamily-Ligand. Nuclear Receptor Superfamily represents one of the most important families of drug targets in pharmaceutical development. Nuclear Receptor) Superfamily-Ligand is a novel public NR-related chemical genomic database that is primarily focused on the correlation of information between NRs and their ligands. It provides correlation data between NRs and their ligands, along with chemical information on ligands, as well as access information to the various web databases regarding NRs. These data are connected with each other in a relational database, allowing users in the field of NR-related drug discovery to easily retrieve such information from either biological or chemical starting points. NR Superfamily-ligand database includes structure similarity search functions for the NRs and for their ligands. Thus database can provide correlation maps linking the searched homologous NRs (or ligands) with their ligands; we can gain more detailed knowledge about their interactions and improve drug design efforts by focusing on inferred candidates for NR-specific drugs....
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