Posted by admin on Feb 29, 2024 in |
The plant Opilia celtidifolia, often known as ironwood or Opilia, is indigenous to many parts of Africa. It has a long history of traditional use in African herbal medicine, and its purported therapeutic benefits have attracted interest. An overview of Opilia celtidifolia’s cultivation, the portions used, and the identification of its chemical components are given in this abstract. The savannahs, dry woods, and semi-arid regions of African nations, including Nigeria, Ghana, and Senegal, are the main habitats for Opilia celtidifolia. Information on its controlled cultivation for therapeutic or commercial purposes is still scarce, nevertheless. Various parts of Opilia celtidifolia, including the leaves, roots, stem bark, and seeds, have been traditionally employed for medicinal purposes. Each part serves specific therapeutic applications, such as the use of roots for wound healing and leaves for various conditions. Opilia celtidifolia contains a diverse array of chemical constituents, including alkaloids, flavonoids, polyphenols, and other bioactive compounds. Opilia celtidifolia is a plant with a rich history in African traditional medicine. It is believed to possess...
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Posted by admin on Feb 29, 2024 in |
Rheumatoid arthritis (RA) is a chronic progressive inflammatory autoimmune ailment with multifactorial etiology. The human gut is a massive intricate ecosystem where microbiota, nutrients, and host cells interact extensively to uphold gut homeostasis. Gut microbiota acts as a modulator of immunity and dysbiosis has detrimental effects on health by triggering a persistent inflammatory response that may eventually result in disease. Probiotics are live microorganisms that can normalize gut microbiota and boost the host’s health when administered in adequate amounts. Recent research has demonstrated that probiotics have important roles in the makeup of the gut microbiota, which can prevent pathogenic bacteria from colonizing the intestine, support the host in developing a strong intestinal mucosa defensive barrier, and reinforce the host immune system. Probiotics have positive effects on health, including immune system regulation and anti-inflammatory activity by preventing the release of pro-inflammatory cytokines like TNF-. Probiotics may affect NF-kB, proteasome activity, Toll-like receptors, as well as their regulators and stimuli, at various sites along the MAPK pathway. Because of the close...
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Posted by admin on Feb 29, 2024 in |
Organic chemist has developed the number of heterocyclic compounds. The heterocyclic compounds have gained more attention in medicinal and organic chemistry because of their numerous biological activities. There are various types of the heterocyclic compound available for several biological activities such as antibacterial activity, anticancer activity, antiepileptic activity, antipsychotic activity, antihypertensive activity, antiproliferative activity. Pyrrole, furan, benzimidazole, thiophenol, thiophene, imidazole and indole compounds became more popular heterocyclic compound due to their biological activities, beta- lactam ring system has important role in the design of different antibiotics as well as in the biological activities. Furthermore the recent advancement that occurred in the scheme of heterocyclic compound caught more attention in many product developments. The present review article focused on the heterocyclic compound, classification, nomenclature, importance of heterocyclic compound, history of heterocyclic compound and recent development in the scheme along with their biological...
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Posted by admin on Feb 29, 2024 in |
Unani Medicine is the ancient system of medicine that deals with prophylactic and therapeutic management of various acute and chronic illnesses. Ilaj bilGhiza, Ilaj bit Tadbeer, Ilaj bid dawa and Ilaj bil yad are the essential modes of treatment in Unani Medicine. A broad term Waja’al-Mafāsil covers entire Musculoskeletal disorders (MSDs) like inflammatory, non-inflammatory, infectious, metabolic, and other MSDs in Unani medicine. Pain is the most common and leading symptom of MSDs. Musculoskeletal pain (MSK) is the most complicated and challenging condition for both patients and medical experts. Almost all individuals experience one or more episodes of MSK pain in their whole life span, regardless of age, gender, or economic status. About 47% of the overall population is affected by MSK pain. Of those, between 39 and 45 percent have persistent issues that need medical attention. Chronic MSK pain which is not properly managed can have a negative impact on quality of life and poses significant socioeconomic problems. Roghan Ahmar Jadeed is an Unani pharmacopeial formulation, induces analgesic and anti-inflammatory effects when...
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Posted by admin on Feb 29, 2024 in |
Kaempferia parviflora Wall. Ex Baker is commonly known as ‘black ginger’ which belongs to the family Zingiberaceae. These are mostly found in the subtropical and tropical areas of Asia. It bears various pharmacological properties such as anticancerous, anti-allergic, anti-inflammatory, antioxidant and antimicrobial. Upon the reports we reviewed the plant aromatic rhizomes contained important phytochemicals as terpenoids and flavonoids. Silica gel column chromatography and high performance liquid chromatography analysis has identified methoxyflavonoids in its rhizome extract which can be used in cosmetics as natural anti-aging agent. These extracts have shown anticancer activities against cervical cancer, pancreatic cancer, gastric ulcer, ovarian cancer etc. There are several reports on the cytotoxic activities of rhizome extracts against different cancer cells which are an alternative way for cancer therapy. Also these plants are depleting in forests for which major steps must be taken for its conservation thereby improving its drug yielding potential which would help in various medicinal ways. Thus, the present report deals with numerous pharmacological activities of this plant which has to...
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