Posted by admin on Jan 31, 2024 in |
The population is currently under threat from a new global health emergency called COVID-19 (Coronavirus Disease-2019). The World Health Organization has classified the virus epidemic as a public health emergency of international concern since December 2019, when COVID-19 first surfaced at a seafood market in Wuhan, South China, and spread quickly throughout the world (WHO). In order to inform potential COVID-19 patients about COVID-19 prevention, diagnosis, treatments, and prevention, we have summarized the most recent clinical characteristic data below. We gathered information for this evaluation from a number of research reports, WHO recommendations, and other articles. It is crucial to remind readers that new information on clinical traits, diagnoses, treatment plans, and outcomes for COVID-19 is updated almost hourly. The ailment has affected people to varied degrees all across the world. The patient displays a variety of symptoms, most frequently a fever, cough, sore throat, shortness of breath, exhaustion and malaise. The condition is treated with general care, symptomatic care, antiviral medication, oxygen therapy and the immune system. To...
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Posted by admin on Dec 31, 2023 in |
Alzheimer’s disease (AD) is one of the most well-studied neurodegenerative conditions. It is a debilitating chronic disease of the central nervous system (CNS). Almost 131.5 million individuals are predicted to be affected by the disease by 2050. The main effects of AD are cognitive decline and language problems. One of the factors contributing to AD is the gradual decrease in the brain’s concentrations of the neurotransmitter acetylcholine. The breakdown of acetylcholine is carried out by the increased activity of the acetylcholinesterase (AChE) enzyme within the brain. Many natural and synthetic acetylcholinesterase inhibitors (AChEIs) have been created in order to slow down the progression of the disease over the years. Currently, there are two potential AChEIs (Donepezil and Galantamine) that have shown positive clinical advantages. Furthermore, Rivastigmine is claimed to be an anti-AChE molecule showing the effects similar to Donepezil and Galantamine. The knowledge of specific as well as multitargeted molecules to treat or cure AD is the ultimate route to reach achievements in the field of AD medication. The intention...
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Posted by admin on Dec 31, 2023 in |
Pharmacological research is a complex and challenging field that seeks to understand the effects of drugs on living organisms. In-vivo and ex-vivo methods are two of the most essential tools used in pharmacological research, each with its own advantages and disadvantages. In-vivo methods involve testing drugs in living organisms, typically animals. This type of research can provide valuable information about the effects of drugs on the entire organism, including its metabolism, distribution, and elimination. However, in-vivo research can be expensive, time-consuming, and ethically challenging. Ex-vivo methods involve testing drugs on isolated tissues or cells. This type of research can provide more detailed information about the mechanisms of action of drugs, but it needs to consider the drug’s effects on the entire organism. The use of in-vivo and Ex-vivo methods together can provide a complete understanding of the effects of drugs. In-vivo methods can be used to identify potential new drugs, while ex-vivo methods can be used to study the mechanisms of action of drugs and to optimize their dosage...
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Posted by admin on Dec 31, 2023 in |
The herbal drugs derived from plant sources are used in traditional pharmacopeia and also act as precursor in lab to synthesize medicines at large scale. Acanthaceae is a large family comprising of various medicinally valuable species. In traditional use, the leaves of this family are commonly recognized to alleviate the poisonous bites of reptiles and insects and whole plants for the treatment of external wounds and ulcers. The pharmacological effects evaluated from various species of this family are antibacterial, antifungal, antipyretic, hepatoprotective, anti-inflammatory, cytotoxic, antioxidant, anti-platelet aggression and insecticidal activities. The phytochemicals reported from this family are mainly flavonoids, alkaloids, lignans, benzonoids, fatty acids, terpenoids, tannins and a few triterpenoid saponins. In the present study two genera namely Blepharis and Lepidagathis of the family Acanthaceae were selected with the focus on their traditional use, chemical constituents, and pharmacological activities. Various pharmacological experiments have verified their practice in traditional use and species of both the genera emerged as good source of herbal medicines. However, uncharacterized crude extract was employed in...
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Posted by admin on Dec 31, 2023 in |
Biopharmaceutical technologies used to create biodegradable materials from biological agents fall within a broad spectrum. The production of bioproducts has grown cleaner and more dependable with the adoption of novel biotechnological approaches. The original study objective was to investigate the legal difficulties surrounding the purchase and sale of biological as well as pharmaceutical products. The production, advancement, and application of biosimilars in medical care are all governed by a legal regime. Guidelines are collections of requirements that producers must adhere to guarantee the efficacy and effectiveness of pharmaceuticals as well as the highest possible consumer security against newly produced goods. Control of biopharmaceuticals entails a comprehensive strategic plan to guarantee superior levels of security and performance. The research concentrates mainly on the trade in and out of drugs from Switzerland, Brazil, and India. International drug manufacturers are now given a stronger legal base on which to introduce novel drugs to the marketplace. This licensing process for new pharmaceuticals can take a year or longer because the healthcare regulatory structure...
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