Posted by admin on Apr 30, 2024 in |
Wound infections persist as a significant and persistent challenge within the realm of healthcare, posing numerous detrimental consequences that extend far beyond the affected individuals. These infections, characterized by the infiltration of harmful microorganisms into wounds, encompass a multifaceted predicament that engenders slower healing periods, heightened morbidity rates, and an onerous financial burden on healthcare systems worldwide. Bacteriophages often known as phages, are viruses that selectively target and eradicate bacteria, making them a potentially effective alternative or supplementary treatment for wound infections. This article gives a general summary of what is currently known about using bacteriophages topically to treat wound infections. It goes through the fundamentals of phage treatment, looks at the benefits and drawbacks of phage use, examines the preclinical and clinical data that is now available, and identifies future research paths in this area. The review highlights the potential of bacteriophage-based therapeutics to transform the treatment of wound infections and provides information on the crucial factors to take into account for effective...
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Posted by admin on Apr 30, 2024 in |
The utilisation of electroceuticals in the treatment of Parkinson’s disease is the predominant topic of discussion in this review. Electroceuticals, which are frequently referred to as “bioelectronics medicine,” are the result of the utilisation of electrical impulses for the goal of therapeutic treatment. It has been investigated if electroceuticals could serve as an alternative or adjuvant to the conventional pharmaceutical therapies that are used in the treatment of Parkinson’s disease. The purpose of this review is to conduct a comprehensive analysis of the existing literature concerning a variety of electroceutical modalities. These modalities include deep brain stimulation (DBS), vagus nerve stimulation (VNS), and transcutaneous nerve stimulation (TNS), amongst others. An analysis is performed to determine the efficacy and safety of various methods, as well as to determine their limitations and potential future research areas. While the review comes to the conclusion that electroceuticals have the potential to be an advantageous addition to the arsenal of Parkinson’s disease treatments, it is important to note that further research is required to...
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Posted by admin on Apr 30, 2024 in |
The objective of chronotherapy is to optimize medical treatments taking into account the body’s circadian rhythms. Drug delivery systems that precisely control the release rates or target drugs to a specific site have an enormous impact on the health care system. Over the past few years, pharmaceutical industry has focused its research in the development of various Chrono therapeutic delivery systems. By choosing the optimal time to achieve the desired effect, treatment opportunities may arise, and undesirable side effects minimized. Hence, the long-term interest of both the public and the industry is to develop new and more effective methods on the current study focus – Chrono pharmaceuticals. The present article covers findings about the effects of biorhythms on various disorders, and their implications for drug therapy and also the design of novel chrono pharmaceutical drug delivery systems that might be able to release the therapeutic agents at predetermined...
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Posted by admin on Apr 30, 2024 in |
The demand for Mouth Dissolving Tablet has been increasing for the last decade particularly in geriatric, peadiatric and patient with some sort of disabilities in swallowing. Mouth dissolving tablets are those tablets which when placed in mouth get dissolved rapidly in saliva without the need of liquid and can be swallowed. European pharmacopeia adopted the term Oro-dispersible tablet for MDTs. Mouth dissolving tablets are also known as Fast melting tablets. Oro-dispersible tablets, fast dissolving tablets or melt in mouth tablets. This article reviews the potential benefits offered by MDTs as a oral drug delivery system for various kinds of patients suffering from different diseases and disabilities. Desired characteristics and challenges for developing fast disintegrating drug delivery systems, quality control tests, various techniques used in the preparation of fast disintegrating drug delivery systems like lyophilization technologies, tablet molding method, sublimation techniques, spray drying techniques, direct compression method. It also reviews the patented technologies for fast dissolving tablets, advantages and disadvantages of different technologies for preparing fast disintegrating dosage form, future...
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Posted by admin on Apr 30, 2024 in |
In response to the increasing popularity and greater demand for medicinal plants, several conservation groups recommend cultivating wild medicinal plants. Green Tea is among the most ancient and popular therapeutic beverages worldwide. This product is made from the plant leaf called “Camellia sinensis.” It can be prepared as a drink, which can have many systemic health effects or an “extract” can be made from the leaves for medicine. Green tea contains thousands of bioactive ingredients, which are almost contributed by polyphenols, which play a key role in preventing and treating many diseases. This literature review aimed to illustrate the phytoconstituent and marketed products of the plant “Green...
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