Posted by admin on Oct 31, 2023 in |
Currently, COVID-19 pandemic is a major zoonotic disease that has killed millions of people all over the world. Similarly, Nipah virus (NiV), causes severe acute respiratory syndrome (SARS) along with febrile encephalitis. NiV belongs to the class of paramyxovirus of the genus Henipavirus is a deadly virus that has caused several outbreaks in recent years. Despite the fact that NiV causes a small number of infections, the severity of the disease results in a higher death rate unlike COVID-19 infection. Many research studies termed bats as a natural host for NiV. Recently two NiV strains were identified i.e. NiV-MY (Malaysian strain) and NiV-BD (Bangladesh strain), is the major cause of epidemic in various geographical areas. Various techniques like ELISA, immunohistochemistry and polymerase chain based reaction have been developed for diagnostic purposes. Currently, there is no approved treatment or vaccine available for either people or animals, and treatment is limited to supportive care. In context with current COVID-19 pandemic, health infrastructure in many countries will be incompetent to manage such...
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Posted by admin on Sep 30, 2023 in |
Antimicrobial proteins and peptides are also known as Host defense system. Recently, research in the food industry and therapeutic fields has seen a considerable expansion in the use of antimicrobial proteins. It has a wide spectrum of antibacterial and immunomodulatory properties against infectious bacteria, viruses, fungus, etc., obtained from microbes, plants, animals, and even humans. Antimicrobial peptides can potentially improve the specificity and efficacy of antibiotics by being a promising alternative because microorganisms can’t metabolize them. Regulation, post-transduction modification, ribosome synthesis, etc. are the essential components of the AMP (Antimicrobial protein and peptide) biosynthesis process. Today, AMPs can be developed synthetically based on their activity, source, structure, and species of amino acids. They have the unique ability to rupture the cell wall, which results in cell death. As a novel approach, scientists have determined a few strategies to administer AMPs by formulating with chitosan nanoparticles, gold and silver nanoparticles, and peptide-assembly by producing microgels, mesoporous materials, and other substances that can be applied in the fields of skin disease,...
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Posted by admin on Sep 30, 2023 in |
The most common, intricate, and variable endocrine disorder known as polycystic ovarian syndrome (PCOS) in women is influenced by both genetic and environmental factors. It’s also associated with metabolic disorders like obesity; hirsutism, acne, diabetes, insulin resistance, and glucose intolerance. In addition to lifestyle changes, it can be treated with allopathic, ayurvedic, natural, or herbal treatments. Due to several factors, including expensive cost, the adverse effects associated with using allopathic treatment, and cultural traditions, people have continued to use herbal items for their health benefits. Different plant species, including Liquorice, Cinnamon, Ginseng Saponin, Flaxseed, Spearmint tea, Danggui, Chaste berries, White peony, and Milk thistle, contain both estrogenic and non estrogenic phytochemicals which are both efficient and safe. It has been discovered that herbal remedies are highly regarded, cost- effective, proficient sources of management and treatment for...
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Posted by admin on Sep 30, 2023 in |
Physiotherapy students are a valuable human resource in the realm of medicine. Mental health of physiotherapy students deteriorates due to challenging learning environment and ongoing battle to become certified healthcare providers. Anxiety, stress and depression lead to decreased productivity, poor quality of life and suicidal thoughts. This study shed light on a narrative review of the impact of stress, anxiety and depression on academic performance of physiotherapy students. Studies were found using databases such as PubMed/ MEDLINE, Google Scholar, and Science Direct. A total of 17, 423 papers and other scientific literature were found and this narrative review included 12 of them. The key terms used were “Stress,” “anxiety,” “depression,” “academic performance,” and “physiotherapy students”. In conclusion, more than half of the physiotherapy students were found to be affected by depression, anxiety and stress. Increased levels of these elements have an impact on students’ academic performance as well as their emotional and physical...
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Posted by admin on Sep 30, 2023 in |
Nanoparticles are the modern-day drug delivery system for biocompatible drugs. Numerous products have developed from nanotechnology to develop effective wound healing and inflammatory treatments. Plant extracts (phytoconstituents) have a lot of therapeutically potential because of their distinctive properties, including anti-inflammatory, antioxidant and insulin-sensitizing properties etc. Furthermore, the nanostructure of herbal extracts and phytoconstituents could enhance the bioavailability, influence relieves of the manner of drug carrier systems to the wounded area, and increase permeation ability to the underlying layers of the skin, all of which are essential for the recovery process and treating inflammation. This review emphasizes nano-formulations of plant extracts. Many approaches have already been published for the preparation of metal nanoparticles, including laser ablation, evaporation-condensation, thermal-decomposition, chemical reduction, photochemical processes, and biological methods (Green synthesis of metal nanoparticles utilizing diverse herbal extracts). Some herbal extracts and their phytochemicals are classified as a potential substitute for wound healing and treating inflammation intermediates due to the presence of various bioactive ingredients, the ease of access, and the reduction of adverse effects. Overall, when employed in nano-formulations, various...
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