Posted by admin on Dec 31, 2025 in |
Background: Breast milk is known for its nutritional and immunological benefits, but its potential as a natural analgesic for infants is less explored. This review examines the analgesic properties of breast milk from both scientific and Ayurvedic perspectives. Objectives: To present modern scientific discoveries regarding breast milk’s analgesic potential, explore Ayurvedic perspectives on its healing properties, establish connections between contemporary and traditional knowledge, and highlight potential applications in pain management for neonates and infants. Methods: A comprehensive literature review was conducted using scientific databases (PubMed, Google Scholar, ScienceDirect) and Ayurvedic sources (traditional texts, DHARA, ARP, ABIM). Keywords related to breast milk, analgesia, and Ayurveda were used to identify relevant studies and texts. Results: Scientific studies have identified bioactive compounds in breast milk with analgesic properties, including endogenous opioids, growth factors, and anti-inflammatory cytokines. Ayurvedic texts describe breast milk (Stanya) as possessing healing qualities beyond nutrition. Clinical studies demonstrate the efficacy of breastfeeding and expressed breast milk in reducing pain responses during medical procedures in neonates. Conclusion: The integration of...
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Posted by admin on Dec 31, 2025 in |
The use of 3D printing in the pharmaceutical industry is a relatively recent development that has attracted a lot of attention since it has many advantages over more conventional pharmaceutical manufacturing methods. The design of an appropriate 3D printing system that can produce formulations with the desired drug release may be made possible by technological advancements. The ability of printing technology to develop potentially innovative oral dosage forms is a significant feature in the field of drug delivery. Additionally, it makes it possible for production processes to evolve quickly, safely, and affordably. As a result, this innovative technology is applied widely in the pharmaceutical industry. Also improving patient convenience through 3D printing will increase drug compliance. The pharmaceutical sectors is particularly interested in fused deposition modelling, powder-bed fusion and inject printing processes, which are briefly covered in this paper among other technical advances for creating 3D objects. This innovative technique has great potential for creating different delivery systems and offering polyp ills with individualized patient-compatible formulations. The potential for...
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Posted by admin on Dec 31, 2025 in |
Mutations in the HTT gene cause Huntington’s disease (HD), a hereditary neurological disorder. These mutations lead to the accumulation of the mutant huntingtin protein, which results in neuronal dysfunction and progressively worsening mental, cognitive, and physical symptoms. In Western populations, the prevalence of HD ranges from 10.6 to 13.7 cases per 100,000. Huntington’s disease does not yet have a cure; the main treatments for its symptoms are cognitive and psychiatric issues, chorea, psychosis, and dystonia. Among the therapeutic issues that need to be addressed are poor drug distribution across the blood-brain barrier (BBB) and off-target effects caused by the BBB’s restricted permeability. Nanotechnology provides novel methods and insights that can improve therapy effectiveness, neuroprotection, and customized drug delivery. This review article discusses Huntington’s disease’s aetiology, epidemiology, pathophysiology, symptoms, current treatments, nanotherapy, and ongoing clinical studies. Despite numerous challenges, this review highlights the advancements in nanotechnology for HD therapy, the possibility of overcoming present barriers, improving patient outcomes, and the need for additional research to fully understand long-term health...
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Posted by admin on Dec 31, 2025 in |
Chronic lymphocytic leukaemia (CLL) is a common haematological neoplasm, mainly affecting older individuals, with a higher prevalence in males. Although treatment options have improved, CLL still presents significant challenges, especially in cases that have relapsed or are not responding to therapy. Chimeric Antigen Receptor T-cell The (CAR-T) treatment has arisen as available immunotherapy alternative for the treatment of CLL, harnessing patients T cells which have been designed for combat cancerous cells through genetically engineered receptors. CAR-T therapy, particularly targeting at cluster of differentiation 19 (CD19), has shown significant efficacy in managing CLL, achieving prolonged remission and MRD negativity in certain patients. Nevertheless, obstacles like T-cell exhaustion, cytokine storm, and neural toxicity remain. To address these limitations, new strategies, including armored CAR-T cells and dual-target CARs, are under investigation. Additionally, combination therapies, such as includes combining treatment of CAR-T cells using BTK inhibitors, offer the possibility of increased effectiveness. This investigation assesses the current developments combined with the prospective developments of CAR-T treatment in managing CLL, emphasizing its transformative potential...
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Posted by admin on Dec 31, 2025 in |
Monkeypox is a zoonotic disease, which refers to its ability to be transmitted between animals and humans. The symptoms of the disease are similar to those of smallpox. However, the symptom, swollen lymph nodes, has been observed as the symptom that differentiates it from smallpox. The disease has been a cause of concern around the world due to its high rate of transmission. The most common symptoms of the disease include fever, rash, sore throat, headache, muscular aches, back discomfort, conjunctivitis, mouth sores, chills, sweating, enlarged lymph nodes, and lethargy. The current MPX outbreak has impacted countries on every continent, making it a serious global health threat. The most effective methods to prevent and cure monkeypox remain a mystery. This review outlines the epidemiology, transmission, symptoms, comorbidities, prevention, and management of monkeypox disease. It also examines the clinical therapies, immunizations, and herbal remedies used to control the infection. The condition is known to adversely affect pregnant or lactating women and immunocompromised individuals, who require additional consideration. Thus, the purpose...
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