Posted by admin on Sep 30, 2023 in |
Clinical results of various medical treatments using medical devices demonstrate continuous advances, dealing with multiple types of products covering a vast range of applications in the last two decades. Millions of people rely on medical devices to diagnose and manage illnesses. A typical framework for medical device regulations is a whole product life cycle regulatory system that covers product design, production, premarket gatekeeping, and post-market monitoring. Nevertheless, the present regulatory frameworks are being tested by the diversity and innovation of medical devices. This comparative study serves as the basis for the research, which then examines the function of litigation in regulation and ensuring patient safety by placing medical device litigation within the context of the pertinent regulatory...
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Posted by admin on Sep 30, 2023 in |
To deliver both conventional as well as novel drugs, the oral route was considered as the most preferable one because it reduces patient’s non-compliance, well accepted by the patients, and can also eliminate the discomfort and pain accompanied by parenteral preparations. Even while oral formulations offer numerous advantages, several drawbacks substantially affect bioavailability. In recent years, lipid-based drug delivery techniques have gained more prominence over other nano-based techniques due to their high biocompatibility and increased bioavailability. Nanostructured lipid carriers (NLCs) are one of the lipid-based carriers developed to overcome some major limitations accompanied by solid lipid nanoparticles (SLNs) by replacing specific quantity of solid lipid with liquid lipid. Nanostructured lipid carrier based researches reveal that they can be the most propitious carrier to enhance oral bioavailability of lipophilic as well as hydrophilic drugs This review mainly focuses on some common barriers that affect the bioavailability of orally administered drugs and provide brief explanation of NLC types, components and fabrication method used in NLC formulations. The present review emphasizes the...
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Posted by admin on Sep 30, 2023 in |
Nanotechnology has found its way into most science fields at a tiny scale. Particle of this size and molecules were found to work differently and got diverse applications. Novel drug delivery system leads to the development of Nanocarriers, including Nanoparticles, Nanospheres, Nano capsules, Nano emulsion, liposomes, and Niosomes. The major area for research is to design Nanoparticles that can efficiently manage particle size, surface properties, and drug release. For this to get characterizations of Nanoparticles, it is critical to control their desired in-vitro and in-vivo behavior. Nanoparticles are characterized by their size, surface morphology, and surface charge, using highly advanced microscopic techniques. Colloidal stability is ascertained through zeta potential. Nanoparticles are also characterized by polymer and drug interaction. In-vivo characterization for binding and internalization of targeted carriers to the specific cell and bio distribution study of targeted Nanoparticles could also be confirmed using confocal microscopy. This review covers all the aspects related to the characterization of the pharmaceutical...
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Posted by admin on Sep 30, 2023 in |
In this advanced technological world, the computer has become an indispensable piece of equipment in both office and home. Visual and ocular problems have recently been reported as the most frequently occurring health problem among computer users. Prolonged exposure to radiofrequency radiation affects eyesight and indirectly affects the whole body function. The herbal supplements that improve eye vision are more effective for all age groups and those involved in jobs that cause strain over the eye. Computer Vision Syndrome (CVS) is caused by extensive computer use that reduces eye blinking rate. CVS comprises symptoms like dry eye disease, strain, redness, and irritation. Sight promoters relieve strain, and energize eyes to keep it healthy. They protect and enhance the vision. In Siddha, many herbs and day-to-day disciplines are advised to maintain good vision. This review article discusses the herbs and other disciplines to be followed that will be helpful in the prevention and management of...
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Posted by admin on Sep 30, 2023 in |
Parkinson’s disease (PD) is a common neurodegenerative disorder that affects approximately 2% of the population aged over 65. Dopamine precursor L-3,4-dihydroxyphenylalanine (L-DOPA) is the main treatment to provide symptomatic relief for Parkinson’s disease (PD). However, with long-term administration of L-DOPA, as many as 95% of patients develop several complications. Medicinal plants (MP) and their active components have been used throughout the worldfor the management and treatment of several diseases such as PD. The World Health Organization (WHO) estimates that 80% of population in developing countries, particularly in Africa, use traditional medicine due to financial constraints. Thus, the use of medicinal plants represents the therapeutic response for populations who have difficulty accessing modern drugs and a source of income. Several MP have been administered over a long period, and they have been proven to cure PD. Therefore, this review provides a summary of recent advance of MPand their bioactive compounds involved in the treatment of PD from the year 2018up to...
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