Posted by admin on Dec 31, 2023 in |
Millions of people throughout the world suffer with epilepsy, a neurological illness that frequently results in seizures. Epilepsy has been treated using both allopathic and ayurvedic medicinal methods. Antiepileptic medications (AEDs) are used by allopathic medicine, commonly referred to as contemporary medicine, to manage seizures. Several AEDs have been created recently in allopathic medicine, such as Brivaracetam and Perampanel, which have better effectiveness and safety than earlier AEDs. Background: Approximately 1% of the global population suffers from epilepsy, a neurological illness marked by recurring seizures. Epilepsy is a difficult condition to manage despite improvements in medical technology, with up to 30% of patients still experiencing seizures while receiving antiepileptic medication (AEDs). Conclusion: Epilepsy is increasingly being treated with both allopathic and ayurvedic therapy. There are several ongoing clinical trials for the treatment of epilepsy using both allopathic and ayurvedic drugs. Because it is more practical for their busy lifestyles, has a quick mechanism of action, and is readily accessible, allopathy therapy is preferred by many...
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Posted by admin on Dec 31, 2023 in |
CADD is a powerful method to discover possible therapeutic compounds in conventional drug discovery. It has now surpassed all other high-throughput screening options, commonly used in drug discovery and development. The creation and optimization of several clinically utilized medications have significantly advanced thanks to CADD, or computer-aided drug design. Computer-aided drug design can take one of two methods: (1) Ligand-based (Analogue based) or (2) Structure-based (Target Based). All of these methods rely on MM force fields to represent atomic-level interactions and define molecular shapes, energy, and motion. The two most common approaches to drug design are structure-based drug design and ligand-based drug design. We can learn about drug-receptor interactions from it. Structure-based drug design includes the discovery of binding sites as well as docking and stocking, virtual screening, compound selection, and lead optimization. Quantitative structure-activity relationships (QSAR), pharmacologic modeling and other processes are aspects of the structure-based drug design process. As can be seen, CADD assists in recognizing appropriate pharmacological properties and compatibility to get an advantage in pre-clinical...
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Posted by admin on Dec 31, 2023 in |
Introduction: This paper will provide an overview of the uses, advantages and disadvantages of using ChatGPT in the pharmacy. A new era of personalised and interactive learning is beginning in pharmaceutical education because of ChatGPT (Generative Pre-trained Transformer). Through the use of AI technology, ChatGPT provides adaptive tutoring that enables students to advance at their own speed and receive individualised guidance. Their understanding is improved, and it also encourages a more intense level of engagement. Methods: This study discuss how ChatGPT is very important in enhancing inclusion and accessibility in pharmaceutical education. It explore the incorporation of virtual simulations and practical training fills the gap between academic understanding and real-world application by giving students practical experience before they reach the workforce. It also addresses the importance of considering ethical issues, such as data privacy, bias correction, and finding the right balance between human engagement and technology when using AI in education. Results: The abstract highlights various studies that demonstrate the effective inclusion of ChatGPT in pharmaceutical education. Numerous studies...
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Posted by admin on Nov 30, 2023 in |
Lead comes in a category of toxic heavy metal which acts as a pollutant when present in high concentration in the environment and cause severe effects on the human body. Due to its continuous use its level increases and serves as a serious threat for the society. Lungs and skin are the first organs which get affected by Lead toxicity. Lungs are the most important and sensitive part of human therefore the toxic effects of lead toxicity on lungs cause severe damage. Garlic (Allium sativum) with medicinal properties is being used for various human ailments since ancient times. Due to its anti-cancerous, antidiabetic, antimicrobial, antioxidant activities helps in reducing the lead toxicity in the lungs as well. Garlic is rich in many components such as sulphur compounds, amino acids, vitamins, protein, trace elements thereby making it a potent therapeutic agent. Since, the therapeutic properties of garlic has not been considered up to its best possible level against heavy metal toxicity therefore, this article presents the toxicity of Lead on...
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Posted by admin on Nov 30, 2023 in |
Immunotherapy is among cancer immunology’s fastest and most furious treatment strategies. The therapeutic perspective of checkpoint inhibitors is represented through the Food and Drug Administration (FDA) approvals for their implementation in various malignancies. Efforts to improve results with immunotherapeutic agents have led to the design of advanced treatment strategies. Current pre-clinical evidence estimating immune checkpoint inhibitors in several cancer cell lines has recommended that combinatorial approaches may have better survival results than monotherapy. Experimental trials evaluating combined therapy with anti-PD-1/ PD-L1 plus anti-CTLA-4 checkpoint inhibitors have reported considerable leads in survival indices over single immunotherapy. The therapeutic prospective of combinatorial approaches is focused on nivolumab with ipilimumab for advanced melanoma patients. Combined checkpoint inhibition with anti-PD-1/PD-L1 plus anti-CTLA-4 monoclonal antibodies is being estimated for broadly cancer histological...
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