Posted by admin on Aug 31, 2023 in |
Given their well-known lack of side effects in comparison to pharmaceuticals, natural materials with medical potential are rising in prominence in clinical research. Since the dawn of civilization, humans have relied on plants as a vital resource for healing. Medicines, health aids, pharmaceuticals, dietary supplements, cosmetics and other similar items derived from plants are becoming more popular. In this article, the chemical components and pharmacological effects of Tinospora cordifolia are described. “Guduchi,” a popular name for the plant T. cordifolia, has a long history of use in traditional Ayurvedic medicine. T. cordifolia, most often known as guduchi, is a prominent medicinal plant found across the tropics. The therapeutic benefits of this method are well recognized internationally. The advantages it has for your diet are less well-known. Native Indians and other Indians have long included guduchi [T. cordifolia (Willd.) Hook. F. Thoms] in their diets. It is also recommended for use in Ayurvedic diets. Interest in the plant has surged recently due to the identification of active components from the...
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Posted by admin on Aug 31, 2023 in |
Male reproduction is controlled and coordinated by endocrine factors and therefore, even minute changes can able to interfere with the male fertility. Accumulation of data have shown that the humans are exposed to chemicals that can able to interfere with endocrine factors. Interestingly, published reports have shown that the continuous exposure to such chemicals occurs mainly due to their wide usage in a variety of personal care and daily products such as plastics, food, water, fertilizers, textiles, shampoos, toys and pharma drugs etc. In view of ongoing interest in exposure of humans to such agents and compromised male fertility, there is a major concern and attention towards the endocrine disrupting chemicals among the public, endocrinologists, andrologists and scientific community. These chemicals interfere with the endocrine functions via mimicking their structure, blocking the hormone receptor and/or function of genes and proteins that facilitate normal spermatogenesis and testosterone biosynthesis. The present review provides an overview of endocrine disrupting chemicals on male reproductive health with a special focus on thyroid hormone disrupting chemicals....
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Posted by admin on Jul 31, 2023 in |
In recent years, the transdermal route has emerged as the most advantageous method for medication administration. It overcame several problems associated with the oral mode of drug administration, including significant issues with previous metabolism. To get around this restriction, transdermic administration systems have been created; however, the medications that can be administered via this route still encounter challenges since some of the drugs’ particles are ineffective at efficiently penetrating the stratum corneum. Our scientists and researchers have created a novel technology called as the extremely deformable vesicle system to meet this difficulty. The medicinal molecule, whether synthetic or natural, is combined with vesicles in this method so that it may be delivered to specific areas of the skin. Transethosomes are a unique promise for improved transdermal medication administration via the skin among transferosomes and ethosomes. Nanotransethosomes’ efficient penetration is facilitated by ethanol, edge activator, and phospholipids. The UDV can be used to administer a variety of medication classes via the transdermal route, including anti-arthritic, antibacterial, anticancer, antiviral and...
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Posted by admin on Jul 31, 2023 in |
The absorption of drugs through the gastrointestinal tract is a highly variable process; prolonging gastric retention of the dosage form extends the time for drug absorption. A novel drug delivery system overcomes the physiological problems of short gastric retention by decreasing fluctuations in blood drug concentration with subsequent reduction in undesirable toxicity and poor efficiency. Various approaches have been introduced to prolong gastric residence time, including floating drug delivery systems (FDDS), swelling and expanding systems, polymeric bio-adhesive systems, high density systems, modified shape systems, etc. Bilayer floating drug delivery systems are the most promising drug delivery system, which exhibits a unique combination of floatation and bilayer, leading to prolongation in residence time in the stomach. Floatation is achieved due to bulk density being less than gastric fluids. So, the system remains buoyant in the stomach for a prolonged period, releasing the drug slowly at the desired rate and thus increasing the bioavailability of narrow absorption window drugs. This review entitles the floating drug delivery system principle and current technology...
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Posted by admin on Jul 31, 2023 in |
In terms of providing professional services, the pharmacy profession has expanded significantly and is now recognized as essential to the multidisciplinary delivery of health care. Because pharmacists are vital healthcare professionals who improve patient care and encourage wellness, their position in society’s healthcare is crucial. Pharmacists are sometimes referred to as chemists and druggists in the medical field. Pharmacists work with medications and give accurate information about them. They also assist in the production, formulation, quality control, standardization, compounding and dispensing of various dosage forms so that they can be used to treat a variety of diseases. In the healthcare system, the pharmacist works in various ways, such as Research and Development (R&D) section, developing new drug formulations, and maintaining proper safety and toxicity of the drugs. The pharmacist is important for the frail elderly population in primary care. The role of pharmacists has been expanding around the Globe, in the present time, as an example the COVID-19 pandemic. In essence, pharmacists are essential to the health care system....
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