Posted by admin on Jul 31, 2023 in |
In recent years, the transdermal route has emerged as the most advantageous method for medication administration. It overcame several problems associated with the oral mode of drug administration, including significant issues with previous metabolism. To get around this restriction, transdermic administration systems have been created; however, the medications that can be administered via this route still encounter challenges since some of the drugs’ particles are ineffective at efficiently penetrating the stratum corneum. Our scientists and researchers have created a novel technology called as the extremely deformable vesicle system to meet this difficulty. The medicinal molecule, whether synthetic or natural, is combined with vesicles in this method so that it may be delivered to specific areas of the skin. Transethosomes are a unique promise for improved transdermal medication administration via the skin among transferosomes and ethosomes. Nanotransethosomes’ efficient penetration is facilitated by ethanol, edge activator, and phospholipids. The UDV can be used to administer a variety of medication classes via the transdermal route, including anti-arthritic, antibacterial, anticancer, antiviral and...
Read More
Posted by admin on Jul 31, 2023 in |
The absorption of drugs through the gastrointestinal tract is a highly variable process; prolonging gastric retention of the dosage form extends the time for drug absorption. A novel drug delivery system overcomes the physiological problems of short gastric retention by decreasing fluctuations in blood drug concentration with subsequent reduction in undesirable toxicity and poor efficiency. Various approaches have been introduced to prolong gastric residence time, including floating drug delivery systems (FDDS), swelling and expanding systems, polymeric bio-adhesive systems, high density systems, modified shape systems, etc. Bilayer floating drug delivery systems are the most promising drug delivery system, which exhibits a unique combination of floatation and bilayer, leading to prolongation in residence time in the stomach. Floatation is achieved due to bulk density being less than gastric fluids. So, the system remains buoyant in the stomach for a prolonged period, releasing the drug slowly at the desired rate and thus increasing the bioavailability of narrow absorption window drugs. This review entitles the floating drug delivery system principle and current technology...
Read More
Posted by admin on Jul 31, 2023 in |
In terms of providing professional services, the pharmacy profession has expanded significantly and is now recognized as essential to the multidisciplinary delivery of health care. Because pharmacists are vital healthcare professionals who improve patient care and encourage wellness, their position in society’s healthcare is crucial. Pharmacists are sometimes referred to as chemists and druggists in the medical field. Pharmacists work with medications and give accurate information about them. They also assist in the production, formulation, quality control, standardization, compounding and dispensing of various dosage forms so that they can be used to treat a variety of diseases. In the healthcare system, the pharmacist works in various ways, such as Research and Development (R&D) section, developing new drug formulations, and maintaining proper safety and toxicity of the drugs. The pharmacist is important for the frail elderly population in primary care. The role of pharmacists has been expanding around the Globe, in the present time, as an example the COVID-19 pandemic. In essence, pharmacists are essential to the health care system....
Read More
Posted by admin on Jul 31, 2023 in |
Probiotics are active microbes found in fermented milk products that support the host’s health when taken in sufficient amounts. Probiotics are typically made from strains such as Lactobacilli and Bifidobacteria isolated from the human intestine, breast milk, and conventional fermented milk products. The choice of the optimal probiotic microorganisms is a crucial initial step. Probiotics are utilized to treat allergies, intestinal, liver and numerous metabolic illnesses, and acute and antibiotic-associated diarrhea, which they prevent and treat clinically. Probiotics have the power to control intestinal permeability, maintain a healthy balance of the host’s microbiota, enhance the gut immune system functioning and balances the activation of pro- and anti-inflammatory cytokines. Providing consumers with probiotic formulations that provide the required dose at the end of their shelf life is a major challenge for pharmaceutical companies. Probiotic Lactic acid bacteria and Bifidobacteria have historically been added to fermented dairy products, which are refrigerated and have a short shelf life. Probiotics can now be added to a variety of ‘dry’ food matrices, such as...
Read More
Posted by admin on Jul 31, 2023 in |
To increase patient compliance, safety, and effectiveness, the need for the design and development of a new dosage form has arisen. Novel film technology like buccal film meets all these needs. The buccal film is inserted into the mouth and the medicine is then absorbed via the buccal mucosa. Compared to alternative buccal drug delivery systems such as wafers, lozenges, microparticles, gel and tablets, buccal film is a more appealing and acceptable dosage form due to its small size, dose and ease of administration. Because it avoids first-pass digestion, buccal film is a very efficient dose form that significantly boosts bioavailability. It is more practical than other forms of dosing because it sticks well to the buccal mucosa of the mouth. Not ingesting the medicine is necessary; it is non-irritating and cost-efficient; other benefits include its sleek design, ease of use and biodegradability. Therefore, this dose type is preferred by both elderly and young patients. This review focuses on buccoadhesive drug delivery methods, which are reliant on adhering to...
Read More
