Posted by admin on May 31, 2023 in |
In Indian and Chinese medicine, the herb Bacopa monnieri, (Neer Brahmi) has long been used to treat a wide range of illnesses. Brahmi offers a wide range of pharmacological advantages, including improving memory in the treatment of schizophrenia and Alzheimer’s disease. The effectiveness of Brahmi in scavenging and illuminating as well as comprehensive analyses based on its pharmacological effects on the thyroid are the focus of the current review. Up until April 2022, PubMed, Scopus, and Google Scholar were searched to find information about the effectiveness of Bacopa monnieri in treating thyroid disorders. The review’s conclusions provide an overview of the information gathered over the preceding five years from various platforms and database libraries. For all calculated data, a number of outcomes were combined into verified constructs to enable direct comparisons. Four papers satisfied the criteria for inclusion in this review. This extensive study provided a summary of Bacopa monnieri’s effectiveness in scavenging free radicals and deciphering thyroid disorders. It’s time to move on to other prevalent problems because...
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Posted by admin on May 31, 2023 in |
Medicinal plants are a huge treasure for mankind and a source of remedy for all illnesses as they are storehouses of bio-actives. The therapeutic efficiency of formulations and medicines depends on using standardized plant extracts, as The World Health Organization emphasized. The present documentation on the medicinal plant Pisonia grandis covers its pharmacological, phytochemical, biological standardization studies and the quantification protocols for the bioactive pinitol and bioactive allantoin earlier reported from this plant. This documentation sheet will aid as a reference for formulating Pisonia grandis-based herbal medicinal...
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Posted by admin on May 31, 2023 in |
Pyrazolines, among the various 5-membered heterocyclic compound derivatives, have drawn attention towards it because of their various pharmacologic activities. They are nitrogenous heterocyclic compounds containing two nitrogens in the adjacent position, which possess considerable biological activity. The synthesis of pyrazolines was initiated after the pioneering work of Fischer and Knoevenagel in the late 19th century. Later, Claisen-Schmidt condensation, and Aldol-condensation, became the most popular methods for the preparation of pyrazolines nowadays. It has been an exciting area of pharmaceutical chemistry to research the biological evaluation of pyrazoline derivatives. The review provides different methods for the synthesis of pyrazolines by Claisen-Schmidt condensation, Aldol-condensation, 1,3-Dipolar Cycloaddition and its biological activities like anti-inflammatory, anti-tubercular, hypotensive, Cannabinoid CB1 Receptor Antagonist activity, anti-viral, etc. It also gives information regarding different possible docking targets and examples in figures. This review article will help explore novel pyrazoline analogues for challenging pathophysiological...
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Posted by admin on May 31, 2023 in |
The global pharmaceutical sector is in vital need of both Innovative technology for solutions and basic science, allowing the production of highly engineered drug products. Commercial-level manufacturing of Complex drug delivery systems utilizing current technologies is challenging. Work within the pharmaceutical trade has been restricted for an extended time to the analysis and development of the latest active compounds; in the meantime, the structure of the assembly, dominated by batch-wise technologies, has not been modified until now. This review covers vital components of producing sciences, starting with risk management ways and design of experiments (DoE) techniques. Experimental techniques ought to, wherever attainable, be supported by process approaches. Thereupon regard, state-of-art mechanistic method modeling techniques square measure represented intimately. Implementing materials science tools paves the thanks for the molecular-based process of future Drug delivery systems. A pic of a number of the prevailing tools is bestowed. This review addresses fundamental tools for increased process understanding and perspective on future process...
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Posted by admin on May 31, 2023 in |
Passiflora foetida, commonly known as stinking passion flower has been used as traditional medicine in treating diseases such as throat infection, giddiness, liver disorder, diarrhea, tumor, nervous disorder, anxiety; sleep disorders, skin infections, hysteria and asthma. In addition, P. foetida has been reported to have potential antioxidant, anti-inflammatory, antiepileptic, anti hyperglycemic, cardio protective, anti-diarrheal, and anti-cancer properties. Metabolites isolated from this plant are mainly flavonoids, polysaccharides, α-pyrones and cyanohydrins. The compounds have been isolated from the leaves, stems, seeds, resins and fruits. The stems of P. foetida have high cellulose content. The leaves and fruits of Passiflora foetida have high nutritional value that they find use as herbal tea, tablets and nutritional powders. Vitexin was quantified by a high-performance thin-layer chromatographic technique. These compounds tend to have diverse biological properties. This review article highlights the secondary metabolites, quantification of phytochemicals, proximate parameters, chemical constituents their activities and...
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