Posted by admin on Nov 30, 2022 in |
Normally, there are two major sexual grievances in men; Erectile dysfunction or impotence and premature ejaculation. Premature ejaculation (PE) is a condition where the orgasm or the emission of semen occurs sooner during sexual intercourse. Erectile dysfunction (ED) is a sexual dysfunction mainly characterized by the inability to either develop an erection or maintain an erection of the penis during sexual intercourse. ED is found to be more prominent in elderly and mature men. As reported in the previously conducted studies, the health-related influences for ED include hypertension, dyslipidemia, diabetes, depression, and heart ailments. As the age increases, the prevalence also increases, especially the age group of 60 to 69 years showed the highest incidences of ED. The median age was of 65 years among all the participants reporting ED. With the increasing tendency in life expectancy in the western countries, and the high prevalence of health ailments like diabetes and various Cardiovascular disorders, the impact on lifestyle and eminence of life imposed by ED in men is likely...
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Posted by admin on Nov 30, 2022 in |
Even though viral hepatitis is a major public health concern around the world. It now has the attention and financial support of global health decision-makers. Every year, over 1.4 million individuals die due to viral hepatitis-related cirrhosis and liver cancer, with the majority of the population being unaware of their illness. This demographic has numerous challenges, including a profound ignorance, bias, inadequate access to health resources, and the implementation of innovative programs and policies. Even after implementing new strategies to manage the illness in recent years, the projected decline has not been evident. The study’s major goal is to show current global illness frequency levels and investigate precautionary measures. The study’s information and findings came from published scientific publications, online sources, and various search...
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Posted by admin on Nov 30, 2022 in |
Cancer has evolved as a detrimental disorder alongside cardiovascular diseases. Plant-derived natural products have been the most successful source of potential anti-cancer drugs and for the isolation and characterization of novel compounds. Till now, only about 10% of the world’s biodiversity has been assessed for biological activity and numerous useful natural lead compounds are expected to be discovered in the near future. The exploration for anti-cancer agents from plant sources commenced in 1950s with the discovery of alkaloids; vinblastine and vincristine from Catharanthus roseus and the segregation of the cytotoxic podophyllotoxins from Podophyllum peltatum. Subsequently, paclitaxel or taxol was isolated from Taxus brevifolia bark and camptothecin was isolated from Camptotheca acuminata. Likewise, homoharringtonine, elliptinium, combretastatin A-4 betulinic acid, pervilleine-A, silvesterol, schischkinnin, and montamine are some of the other effective plant-originated anti-cancer compounds. With the developments in structural chemistry, a range of synthetic and semisynthetic lead compounds were designed and developed in laboratories. For instance, the semisynthetic analogues of vinca alkaloids are vinorelbine and vindesine, which are used either alone...
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Posted by admin on Nov 30, 2022 in |
Heterocyclic chemistry has grown very rapidly, particularly in evaluating synthetic methods and investigating synthesized materials’ bioactive properties. Heterocycle compounds are important in many facets of life’s pharmacological activities. In their structure, many biologically active compounds such as amino acids, vitamins, hormones, nucleic acids, alkaloids, dyes, and drugs (natural and synthetic) possess heterocyclic ring molecules. Various pyrazole derivatives and their numerous physiological and pharmacological effects have been the subject of numerous investigations during the last decade. Part of the goal of these investigations was to uncover the vast spectrum of drug-like properties of pyrazole derivatives and their structure-activity connections to unlock the full potential of these molecules. This article focuses on the chemistry and pharmaceutic activity of the heterocycle pyrazoline, i.e., nitrogen-containing five-membered ring. An account of a different mode of synthesis from different starting materials is shown, along with the highlights of the therapeutic activity of...
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Posted by admin on Nov 30, 2022 in |
In order to discover new treatments for a wide range of ailments, ethnopharmacological research has investigated different leads from plants. In nature, the Orchidaceae family’s Vanda roxburghii is found in Bangladesh and India. As a remedy for dyspepsia, bronchitis, and inflammations, as well as for rheumatoid arthritis and bronchitis, various portions of the plant are employed. A number of the plant’s beneficial compounds have been identified, including alkaloids, glucosides, fatty acids, saponin, and tannin compounds, as well as β- and γ-sitosterols, as well as fatty oils, resin, and tetracosylferrulate in the roots. In the angiosperm family, orchids make up the largest and most diversified group. They are grown for their magnificent blooms. Flowers of all sizes, shapes and colors can be found on these plants. However, these plants have been widely recognized for their economic relevance, but little attention has been paid to their medical properties. Ayurvedic practitioners have long relied on orchids to treat a wide range of diseases. For centuries, people have relied on the herb to...
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