Posted by admin on Dec 31, 2022 in |
Liposomes are considered to be safe for usage; they have been used hugely in cosmetics. Biologically obtained compounds of phospholipids have a high affinity to the skin’s surface. Liposomes are highly permeable and have more storage capacity on the stratum corneum and also it is considered a chemically active agent to the skin. Most future studies on liposomes involve drug delivery in cosmetics. Liposome formulations are prepared from phospholipids of variant sources like egg and soya; they were differentiated in terms of their result on the skin like water content, Elasticity, Barrier function. Liposome has a variety of phospholipids giving a variety of effects on the skin humanity. Antioxidant and anti-inflammatory activity is a category poses by the plant of phenolic compound metabolite. The ideal property of the compounds are stable and also act as a bioactive ingredient in plants, but it will give the property after the process of extraction; they are considered to be very sensitive to light and heat sources; they have the property like speed...
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Posted by admin on Dec 31, 2022 in |
The most commonly used analytical method in drug research is reversed-phase high-performance liquid chromatography (RP-HPLC). RP-HPLC methods also use huge quantities of solvents and generate by-products that must be disposed of, posing environmental and operator health worries. Micellar Liquid Chromatography (MLC) is a green chromatographic process for pharmaceutical analysis in which surfactants are applied above the Critical Micellar Concentration in the mobile phase (CMC). The ability of micelles to solubilize compounds that are not soluble or sparingly soluble in water is one of their properties; this property is critical for advancing analytical methods. MLC is also compliant with current RP-HPLC systems. As a result, no changes to the current RP-HPLC instrument are needed. MLC (micellar liquid chromatography) is a green and long-term method for analyzing medication compositions. MLC is not only the more environmentally friendly option, but it is also the more cost-effective. It is believed to have a mobile phase of 90% or more water (v/v), which can be recycled if injection volumes are small and far apart....
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Posted by admin on Dec 31, 2022 in |
Metformin (MET) is a biguanide class of oral hypo-glycaemic agent which is used in the treatment of diabetes mellitus type II. Currently, MET is the first drug of choice and is primarily prescribed by medical practitioners to at least 120 million people worldwide. The quality-oriented routine analysis of various commercially available products of MET is a major challenge. Several methods have been reported in an industrial scale for thorough quantitative analysis. This review article comprehensively examines the published sophisticated instruments-based nearly 50 analytical methods in various pharmaceutical databases like Google Scholar, PubMed, etc. of diverse area of High-Performance Liquid Chromatography (HPLC). The determination of MET in plasma, serum, and urine, extensively requires the HPLC method. For the determination of MET in biological samples, we recommend the LC-MS/MS method since this method combines the HPLC separation ability with MS sensitivity and selectivity, allowing the identification of MET and its metabolites. For pharmaceutical analysis, HPLC with UV detection method is applicable because this method provides accurate results and low cost compared...
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Posted by admin on Dec 31, 2022 in |
The eye is one of the most sensitive organs of human body and is continuously exposed to different environmental agents so it is very important to take care of eyes. Poor vision makes it harder to read, drive, and cook. Many eye problems and diseases can be treated if caught early. Ophthalmologists will examine eyes for signs of vision problems or eye diseases. It’s the best way to find out if glasses or contacts are needed in the early stages of a serious but treatable eye disease. Wearing protective eyewear when playing sports or doing activities around the home, smoking cessation, wearing UV radiation-blocking sunglasses, Cleaning hands and contact lenses properly to avoid the risk of infection, etc., are the steps to protect...
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Posted by admin on Dec 31, 2022 in |
Nanoparticles with lipids as a constituent are called “solid lipid nanoparticles” (SLNs). Based on the most recent trends, SLNS is a promising approach for overcoming multiple barriers in drug delivery. Through SLNs, maximized drug payload to the site of action for different pharmaceutical drugs can be achieved. They range in size from 10nm to 1000nm and possess a solid lipid core matrix that aids in the solubilization of lipophilic compounds. The evolution of multidrug resistance therapy against various chemotherapeutic agents, tissue toxicity, and a high prevalence of drug-resistant tumors are the most common impediments in the clinical management of cancer. For more than a decade, SLNs have been widely used as drug delivery systems in the treatment of various cancers due to their low toxicity, high drug bioavailability, and usefulness with hydrophilic and lipophilic drugs. In this review, we discussed the incorporation and controlled delivery of different cytotoxic anti-cancer drugs to target sites using SLNs to treat various...
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