Posted by admin on Aug 31, 2022 in |
COVID-19 is a disease caused by SARS-CoV-2 that can trigger respiratory tract infection. Due to its tendency to affect the upper respiratory tract (sinuses, nose and throat) or lower respiratory tract (windpipe and lungs), this disease is life-threatening and affects a large number of populations. This virus’s unique and complex nature enhances the scope to look into the direction of herbal plants and their constituents for its prevention and treatment. The herbal remedies can have preventive as well as therapeutic actions. This review focuses on various aspects of using herbal medicines for COVID-19, as herbal constituents may also have adverse effects. Various studies revealed that some medicinal plants show life-threatening adverse effects, so selecting plants, and their related studies should be appropriate and strategic. This article includes various factors that should be considered before herbal drug use in COVID-19 patients. These are clinical trials, safety, molecular mechanism, and self-medication, which have been elaborated. This article also discusses the targets of covid-19 and different coronavirus strains. As before, treatment diagnosis...
Read More
Posted by admin on Aug 31, 2022 in |
3D printing is an emerging technological advancement that could be applied in several medical fields, the educational arena, and preoperative planning. 3D printing technology, also known as additive manufacturing, is significant as it is cost-effective compared to traditional cadaveric models. The purpose of writing the current review on 3D printing techniques was to compile the recent literature with a special focus on the methods, principles, and fabrication mechanisms to generate 3D printed models. The novel technology is reliable and appropriate for analyzing congenital heart diseases, but 3D printing has limitations and potential bias about subjectivity in the modernization of treatment for congestive heart diseases. 3D models can serve as a summary of diagnosis and a reliable tool for the choice of disease treatment. Albeit, high-resolution 3D printing methods are still in the initial stage of development with limitations, they demonstrate a huge potential to manufacture multi-functional materials. The present review briefly explains the applications, limitations, and regulatory challenges to be overcome in the fabrication of 3D printed...
Read More
Posted by admin on Aug 31, 2022 in |
The interaction/incompatibility of drug excipients is a major concern in formulation generation. Compatibility tests for drug excipients constitute an important step of the production of all dosage forms in the preparation stage. The possible physical and chemical interactions of drugs and excipients can influence chemical, physical, therapeutic properties and the dosage form’s stability. The current review involves a fundamental mode of drug degradation, a process of physical, chemical and biopharmaceutical interaction between drugs and excipients. The study of incompatibility is explored in various thermal and nonthermal methods. Once the interaction form is identified, further steps can be taken to enhance drug and dose stability. Current and potential reviews of case studies relating to drug and excipient interactions and their unavoidable incompatibilities have also been studied to deepen greater information about such drug solution scenarios. From the review, we conclude that the subsequent use of the thermal and nonthermal methods provides information for the drug-excipient interaction, which can aid the production of safe dosage forms by selecting an...
Read More
Posted by admin on Aug 31, 2022 in |
Litsea, an outsized genus comprising 400 species of evergreen trees or shrubs, distributed chiefly in tropical and subtropical Asia, Australia, and therefore the Pacific Islands, belongs to the Lauraceae. Litsea polyantha is found throughout North, East, and Central India at an altitude of 1,200 m. It is often planted as an ornamental plant. It is mostly grown as an honest source of fodder for the livestock. It is alittle to medium-sized evergreen tree attaining a height of 21 m and a girth of 1.8m. Barks are dark grey or pale brown colour, exfoliating in quite small polygonal corky scales. In Folklore medicines-Bark, Stem, Roots and Leaves are wont to treat various diseases and disorders. The bark of Litsea polyantha is mildly astringent and used for diarrhea. Powdered bark and roots are used for pains, bruises, contusions and for fractures in animals. Previous chemical investigation of this plant has revealed the presence of beta-sitosterol and actinodaphnine within the bark and an arabinoxylan containing D-xylose and L-arabinose during a molar ratio...
Read More
Posted by admin on Jul 31, 2022 in |
Background: Guanfacine is a drug used to treat ADHD (attention deficit hyperactivity disorder) and treatment for hypertension from 1986, approved by the FDA. Recently it had been deduced that Guanfacine could also be employed in smoking cessation as a pharmaceutical aid. This could be attributed to the physiological effect that the drug has on the human body, such as decreased heart rate and blood pressure. An increase in heart rate and blood pressure leads smokers to light up a cigarette to ease their stress. Therefore, Guanfacine could be used potentially for nicotine cessation. Guanfacine could be used in combination with other conventional drugs already existing for this very purpose. It has to be mentioned that before employing this drug in the use of smoking cessation, a lot more studies have to be conducted with a much greater sample size to assess if there are any other adverse effects or any other limitations which could vary among different individuals and also assess the optimal amounts of dosage that would be...
Read More
