Posted by admin on Jul 31, 2022 in |
Introduction: Autism is a group of psycho-neuro-developmental diseases in which children fail to acquire social interaction and other regular motor and verbal milestones, and some developmental issues are suspected. According to recent reports, prevalence rates have risen drastically from 4-6/10,000 in the early 1960s to 40-60/10,000 now. According to Ayurvedic literature, Unmada is a term for psychotic issues that encompasses many mental conditions, including autism. Aims and Objectives: Critical review and analysis of the effects of various conventional Ayurveda treatment modalities in the management of Autistic children. Material and Methods: Various Ayurveda classics and studies published in journals, as well as PubMed, and Medline databases related to effect of Ayurveda drugs, therapeutic process, and supportive therapy in management of Autistic children, are reviewed and appraised. Review Results: Multimodal management approach of an Ayurveda comprising the herbal supplements, Ayurveda Compounds, Abhyangam, Shiropichu, Shirolepa and a very specific, controlled and wholesome diet and Sattvavajaya chikitsa (Psychotherapy) with supportive therapy. These Ayurveda therapeutic approaches are used to manage autism with respect to...
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Posted by admin on Jul 31, 2022 in |
Cardiac remodeling is a progressive morphological change of the myocardium in response to various pathophysiological overloads. Cardiac remodeling occurs due to various mechanisms associated with GPCR and growth receptors. Fundamentally cardiac remodeling is an adaptive mechanism of the myocardium against various overloads. However, depending upon the frequency, strength, and type of overload, these mechanisms can be physiological or pathological. Physiological cardiac remodeling results from controlled overloads that aggravate myocyte hypertrophy and angiogenesis. Pathological remodeling occurs because of excessive overload-induced mechanisms responsible for the over-activation of the immune system and cardiac fibrosis. This review covers the harmful and protective effects of cardiac remodeling and several anti-hypertrophic mechanisms co-occurring. Reviewed literature designates cardiac remodeling as a protective mechanism of myocardium against cardiac overload. However, the overactivation of several inflammatory and other related mediators during cardiac remodeling is liable for its harmful...
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Posted by admin on Jun 30, 2022 in |
Mycosis is an opportunistic infection that attacks patients who are immunocompromised. Our immune system is designed to defend us against fungus and bacteria. The fungus can expand, penetrate and kill tissue because it lacks immunity. It’s everywhere, in soil and air and even in healthy people’s noses and snot, says the researcher. “As we work to defend ourselves from COVID-19 and live with it, another hazard termed Mucormycosis has emerged. Mucormycosis, a fungal infection caused by Mucor with a 50% fatality rate, maybe provoked by the administration of steroids, a life-saving treatment for severe and critically ill Covid-19 patients. Stay safe from Mucormycosis, a fungus that has been discovered in Covid-19...
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Posted by admin on Jun 30, 2022 in |
This manuscript aims to figure out updated information on the dry coating of powder (DCP). In pharmaceutical processes, the inevitable is handling of fine and ultra-fine particles (FUFP). Their higher surface area associated surface and surface attributes contribute chiefly to exhibited complex phenomenon like bulk behaviors, physicochemical property, performances and functionalities of pharmaceutical importance, and many others. Nowadays particle engineering techniques are extensively exploited to modify surface and surface attributes of FUFP to find their worthy applications and new functionalities. Among available diverse techniques for particle engineering DCP is advocated as a worthy and efficient one. The DCP is considered to have multidisciplinary applications in drug development and drug delivery. Process basis of DCP calls for attaching and/or fixing the particles of coating material (PCM) or guest particle (GuP) onto the substrate/core particle (S/CP) or host particle (HoP). Fixing/ attaching the PCM onto HoPs mandates their interaction that may be mechanical, chemical, thermal, electro-chemical and many others. Scientific literature and patents are evidencing diverse processes and methods for interacting...
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Posted by admin on Jun 30, 2022 in |
Herbal plants have long been known to have antifungal properties. The medicinal plants are prospective in aquaculture as an alternative to antibiotics and other anti-candida drugs. This article aims to review the reported herbal medicines with their research findings that have an enormous future prospective for the effective treatment of Candida infections. Various species of Candida were classified and their pathogenesis and mechanism of action were highlighted. Mechanisms of action of commonly used synthetic anti-candida drugs were compared to that of the herbal plants. Recent plant-based antifungal activity studies were analyzed. Ten species of candida, namely Candida albicans, Candida glabrata, Candida parapsilosis, Candida krusei, Candida dubliniensis, Candida lusitaniae, Candida guilliermondii, Candida rugosa, Candida zeylanoides and Candida tropicalis were found to be responsible for infection in human. Plant-based natural products were found to produce anti-candida actions based ongermination inhibition and formation of biofilm, cell metabolism, cell wall integrity, cell membrane plasticity, and induction of apoptosis. Around 20 research works were analyzed, and it was found that the majority of the...
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