Posted by admin on Apr 30, 2021 in |
Synthesis of silver nanoparticles using fruit extract has been gaining considerable attention as an eco-friendly approach in green chemistry. The present work reports the synthesis of Muntingia calabura silver nanoparticles (McAgNPs) by the addition of an appropriate amount of Muntingia calabura fruit extract to the aqueous AgNO3 solution under constant stirring at room temperature for 24 h. The addition of fruit extract leads to the formation of stable colloidal silver nanoparticles. The peak obtained at 460 nm using UV-VIS spectroscopy confirmed the formation of silver nanoparticles. Scanning electron microscopy analysis showed the spherical and oval morphology of the silver nanoparticles. Energy-dispersive X-ray spectroscopy (EDS) analysis indicated the abundance of silver nanoparticles in chemical composition. DLS/ZETA POTENTIAL analysis was applied in order to measure the particle size distribution and nature of the surface charge of the McAgNPs. Further, the antibacterial activity against the silver nanoparticles was...
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Posted by admin on Apr 30, 2021 in |
Nano robotics is an emerging, advanced and multidisciplinary field that calls for scientific and technical expertise of medical, pharmaceutical, bio-medical, engineering as well as other applied and basic scientists. Nano robots differ from macro-world robots specifically in their Nano-sized constructs. Due to their small size and wide functional properties, nano robots have created exceptional prospects in medical, biomedical and pharmaceutical applications. Although, no technology is available to construct artificial nano robots, it is now possible to create nano robots by using biological means. Nanorobots, nano machines, and other nano systems are objects with overall dimensions at or below the micro meter range and are made of assemblies of nanoscale components with individual dimensions ranging approximately between 1 to 100 nm. Smaller the size, larger is the specific surface area and energy efficiency. This is the prime concept behind all micro or nanotechnology devices. Even though the nano robots have not yet been deployed in any commercial application with currently available science and technology, the ongoing intensity of research and...
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Posted by admin on Apr 30, 2021 in |
An alternative, economically viable, and laboratory-friendly synthetic method described for the preparation of Bimatoprost, an anti-glaucoma drug. Stereospecific synthesis of Bimatoprost has been achieved with commercially available (-) Corey lactone i.e., diol, as a starting material. To our delight, the replacement of the benzoyl (Bz) group with Tetrahydropyranyl ether (Thp) protection resulted in yield improvement. Tetrahydropyranyl ether (Thp) is notorious as a useful protecting group for alcohols in organic synthesis. It has numerous benefits, such as low cost, ease of insertion, general stability to most non-acidic conditions. It offers good solubility and easy to remove if the functional group it protects requires manipulation. Moreover, it described the successful application of luche’s reduction for the conversion of α, β-unsaturated ketone 8 to allylic alcohol 9 using CeCl3 7H2O, NaBH4. This lanthanide combination with borohydride enables the selective 1, 2-hydride attack on the carbonyl group, instead of an undesired 1, 4-hydride attack, which leads to the formation of desired allylic alcohol without disturbing the double...
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Posted by admin on Apr 30, 2021 in |
The present study reveals the importance of inclusion of knowledge regarding infectious diseases and their effect on the respiratory system in the school education system and in pharmacy courses. An integrative review of diseases that affect respiratory tract along with COVID 19. Family plays an important role to give protection from any kind of infectious diseases based on the achieved knowledge. Thus the education of consciousness in each and every family about the infectious diseases is very important, particularly mother and head of the family must be well equipped with the knowledge of infectious diseases including RTI etc. and then the only large population can fight against COVID 19 like pandemic with minimum mortality and fit society with the good financial system. To restructure the syllabus content in the school education system so that in each and every age, students are compulsory to be knocked about the infectious...
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Posted by admin on Apr 30, 2021 in |
The aim of the present study is to apply the Design of Experiments (DoE) to develop an assay method for the separation of amino acids by RP-HPLC. The method used in this study is the DoE Combined- Randomized method. Design of Experiments allows interpreting the results with better outcomes and enhanced understanding process. Ion pair reagent- Octane 1 Sulphonic acid sodium salt monohydrate of 0.01M at pH 2.2 is used along with Methanol and Tetra-hydro Furan. The column used is INETSIL C8, with 5µ Particle size and 4.6×250 mm column dimensions. The Solvent composition and ion pair concentration is evaluated as variables in the DoE. The wavelength for all amino acids is 205 nm. Conclusively DoE is an efficient tool for the separation of amino acids. Method development was established, and the design is validated. The proposed method has adequate reproducibility and accuracy for the estimation of the amino acids in the routine...
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