Posted by admin on Nov 30, 2022 in |
Phage therapy has become a successful alternative to conventional antibiotic therapy due to the increasing number of multidrug-resistant bacteria in most clinical settings. Various factors like phage adsorption to the host site and phage neutralization by the host determine the efficacy of phage treatment. However, external factors like temperature and pH are critical in deciding the success of using phages in therapeutics. The high stability of phages under both favourable and unfavourable conditions guides their stability in phage therapeutic preparations as well as at the site of infection. In the present study, we exposed the phage to different pH and temperature combinations. The phage showed statistically significant activity at pH 7 and 8 compared to pH 6. In terms of different exposure temperatures, the phage showed good antibacterial activity at temperatures between 31 0C and 40 0C. A combination of pH 7 with temperature 380 C showed the highest recovery of the phage; however, stability was seen in a considerable range of temperature and pH. The lytic activity of...
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Posted by admin on Nov 30, 2022 in |
Even though viral hepatitis is a major public health concern around the world. It now has the attention and financial support of global health decision-makers. Every year, over 1.4 million individuals die due to viral hepatitis-related cirrhosis and liver cancer, with the majority of the population being unaware of their illness. This demographic has numerous challenges, including a profound ignorance, bias, inadequate access to health resources, and the implementation of innovative programs and policies. Even after implementing new strategies to manage the illness in recent years, the projected decline has not been evident. The study’s major goal is to show current global illness frequency levels and investigate precautionary measures. The study’s information and findings came from published scientific publications, online sources, and various search...
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Posted by admin on Nov 30, 2022 in |
Rungia parviflora belongs to the family Acanthaceae (Linn.). The dried and powdered leaves were extracted with ethanol in Soxhlet’s apparatus for 12 hrs. The extract was subjected to toxicity studies at the doses of 5, 50, 300, and 2000 mg/kg under the observation of 24 hrs. An acute toxicity study of ethanolic extract was found to be toxic (1/2 of rats died) at a dose of 2000 mg/kg, orally. Hence, it was taken as LD50. Further, the hepatoprotective activity of Ethanolic extract at the dose level of 250mg/kg and 500 mg/kg ware studied in Wistar male rats against thioacetamide (400mg/kg p.o.) induced hepatotoxicity. Silymarin 100mg/kg p.o. was taken as a standard hepatoprotective drug. The hepatoprotective activity was studied by determining the parameters like SGPT, SGOT, Total Bilirubin, ALT, Pentobarbitone induced sleeping time, Ascorbic acid content in urine, in-vitro Bromsulphalein uptake test and Histopathological observation of liver. Overall study indicated that ethanolic extract of leaves of Rungia parviflora at a dose level of 250mg/kg and 500mg/kg significantly protects the liver...
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Posted by admin on Nov 30, 2022 in |
Since ancient times, man has been looking for plants to rescue from diseases and improve immunity. He may find the right choice of plants by trial and error, observing nature and following theories, and passing that information to the next generation by word of mouth. Folklore medicine combines traditional healing practices, spirituality, and therapies to diagnose and prevent ailments. In the present study, a survey was carried out about the traditional usage of medicinal plants in herbal healers, old and native peoples of Pathinettamkottai village, and its surrounding areas of Sivagangai district in Tamil Nadu. The study explored 65 medicinal remedies from plants used to treat 41 different illnesses. The predominant part used to prepare medicines is a leaf. The medicines are prepared in the form of powder, paste, decoction, and vapor, and they are used to cure 31 health problems like cold, fever, asthma, diarrhoea, diabetes, jaundice, rheumatism, wounds, cuts, stomach pain, etc., The survey provides rich source of knowledge on plants and, thus new...
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Posted by admin on Nov 30, 2022 in |
The effect of many plant extracts and microbial biopesticides on insects’ different developmental stages and physiology have been widely studied from time to time, but the effect of microbial biopesticides on the mosquito tissues, especially mid gut tissues, is very few. Since the malaria vector is one of the most important inclusions in human health and mosquito-borne diseases represent a great health threat in tropical and sub-tropical climates, it is quiet logical to know the detailed mode of action of fungus on Anopheles stephensi (L.) larvae after assessing the bio toxicity. In the present study, we have mainly emphasized the midgut of Anopheles stephensi (L.) to understand better the larvicidal action of fungal biopesticide Beauveria bassiana (Balsamo). After treatment with the fungus Beauveria bassiana (Balsamo), the cytopathic effects of the fungus were widespread along the whole anterior and posterior part of the midgut...
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