Posted by admin on Feb 28, 2023 in |
Aim and Objective: The coronavirus disease 2019 (COVID-19) pandemic, caused by the coronavirus-2 (SARS-CoV-2) that causes severe acute respiratory syndrome, is the world’s most serious health issue. COVID-19 is currently without a precise and successful antiviral treatment. Phytochemicals provide a ray of hope for public well-being amid the pandemic, and much study is being done on them. Materials and Methods: Cinchona bark contains phytochemicals that have been used as antiviral agents against various viruses because they can suppress various viruses via various mechanisms of direct inhibition at the viral entry point and replication stages via immunomodulation potentials. Cinchona bark and its components have also been shown to have promising antiviral properties against SARS-CoV-2, according to recent data. This narrative analysis summarizes cinchona phytochemical agents, their mechanisms of action, and possible antiviral behaviours against the SARS-CoV-2 virus. Results and Discussion: Medicinal plants and their extracts and herbs have shown positive results in combating SARS-CoV-2 infection and could help treat COVID-19 patients as alternatives to care under phytotherapy approaches during this...
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Posted by admin on Feb 28, 2023 in |
Carbazole comprises an important class of heterocycles. Carbazole is a tricyclic molecule having a coal tar carbon backbone. Also, it has the structural properties of numerous compounds used in electronics for manufacturing polymers or dyes and electroluminescent materials, owing to its luminous quality. It has been reported that diverse biological activities include anti-cytotoxicity, bacteria-related problems, neurological problems, etc. Some carbazole derivatives were created such carbazoles with N-substitution, benzocarbazoles, furocarbazoles, pyrrolo-carbazoles, imidazo-carbazols, etc. Researchers have gained interest in N-substitution derivatives because of their active participation in neuro-related disorders and cell...
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Posted by admin on Feb 28, 2023 in |
Karkatshringi (Pistacia integerrima) is an essential Ayurvedic medicinal plant belonging to the family Anacardiaceae. The plant originated in India and grows in the ranges of the north-western Himalayas. It is distributed over China, Afghanistan, Pakistan, and Nepal. The flowers of this plant is small and red, fruits are shiny and brown. Galls are hollow, horn-shaped, bitter and used for medicinal purposes. Gall powder is most commonly used in diseases such as cough, diarrhoea, fever, etc. also effective against staphylococci, pseudomonas and Escherichia coli bacteria. The different parts of the plant contain amino acids, sterols, alkaloids, flavonoids, tannins and saponin. In Pistacia integerrima, the volatile chemical constituents are extracted by hydro distillation or liquid-liquid extraction. Pistacia integerrimais associated with fungi which causes rust and blight diseases. Traditionally it is used for rheumatic pain, analgesic, and antipyretic effects. Karkatshringi is an important ingredient of Ayurvedic formulations like Chavyanprash, Dashmularista and Shringyadi Churna. Galls are used in the treatment of diarrhoea. Diabetic patients also use it. Essential oil of Pistacia integerrima was...
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Posted by admin on Feb 28, 2023 in |
The herbal-based formulation “Sugar Care” a product of Miracle Drinks was assessed for an anti-diabetic property on 12 diabetic patients. Each patient was prescribed 15ml of Sugar Care (S10) morning and evening after meal and 15ml of cardiovascular care (S3) in the afternoon. Morning and night doses of sugar care were given along with 15ml of Liver Care (S4) and Renal Care (S5). After 30 days of treatment, the biochemical markers related to blood sugar, like fasting blood sugar (FBS), post-prandial blood sugar (PPBS), and haemoglobin-linked sugar or HBA1C were assessed. A significant reduction of FBS i.e., 50 to 72.2%, was observed in 5/12 diabetic patients. Female patients showed a better recovery rate than male patients, who were 3/4, and 3/8 patients, who showed more than 50% reduction in FBS. A similar recovery trend was also noticed in both male and female diabetic patients that showed a substantial decline in PPBS after treatment with Sugar Care. Three female patients showed substantial change from 346.0±6.0, 420.0±3.0 and 407.3±1.53mg/dl to 158.0±2.0,...
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Posted by admin on Feb 28, 2023 in |
The process of eliminating viral infection and massive control from spreading furthermore by any variants may lead to a pandemic in the near future. On the other aspect, the impact of eradicating by the initial stage to prevent, treat carcinoma to decline the affected and death rate to maximum amount by Molecular Docking. The quickest and easiest method to search out the potential drugs is by analyzing the ligand-protein interactions compared to the traditional ways. Drugs of antivirals and anti-cancer drugs are given for treating viral infections and cancers. Massive kinds of viruses affect humans with several diseases, from self-curable diseases to acute mortal diseases. In cancer, the diseases are known by the cells within humans; multiplication occurs and forming the tumors of malignant cells with the flexibility to be a pathological process. Herbal medicines are known to play enormous role by giving initial priority. Various plant species are being employed to cure or prevent viral infections and cancers. Molecular docking provides a fast understanding of the ligand’s exploration...
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