Posted by admin on Jun 30, 2023 in |
The genus Ailanthus, which includes both evergreen and deciduous species, is native to both Asia and northern Australia. Traditional medicine relies heavily on this plant, and various components of the plant are utilized to treat a wide range of illnesses. Herbal and ayurvedic drugs have gained worldwide attention over the past decade for their potential health and financial benefits. There are now major worries about the quality, safety, and efficacy of herbs due to their regular and extensive use around the world. As a result, credible scientific data or evaluation is required before health claims made about herbs may be considered valid. The foundation for this tree’s status as a plant of heaven includes the traditional assertions, phytochemical studies, pharmacological examination and some ayurvedic formulations. Therapeutic effects are found throughout the plant. The bark is employed in treating dysentery, earaches, skin diseases, rectum problems, fever related to tridosha and alleviating thirst. Furthermore, it is prescribed for patients suffering from bronchitis, asthma, bronchitis, dyspepsia, gout and rheumatism. In Ayurveda, it...
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Posted by admin on Jun 30, 2023 in |
Herbs, which have been used to cure numerous ailments since ancient times, play an important role in building the foundation of modern medications. The present study aimed to investigate the antioxidant potential of nutraceutical dry powder suspension formulated with Moringa oleifera leaves and Celastrus paniculatus seeds extract against DPPH (2,2-diphenyl-1-picryl-hydrazine-hydrate). Plant extracts are prepared using ethanol as a solvent in the Soxhlet apparatus and extracts are evaluated for antioxidant activity using ascorbic acid as standard and best % inhibition of free radicals the dose is selected for formulation. Further evaluation studies are carried out for all the batches to finalize the optimized batch showing good flow properties and drug release profile. Both plant extracts showed good % Radical scavenging activity (%RSA) compared to ascorbic acid’s scavenging activity. The optimized formulation showed acceptable evaluation results, including pH, angle of repose, carr’s index, hausner ratio, sedimentation volume, redispersibility, viscosity and drug release. The formulated dry powder suspension formulation showed good antioxidant activity. Thus, the present investigation revealed that the developed nutraceutical...
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Posted by admin on Jun 30, 2023 in |
Hordeum vulgare (Barley) grass is the best functional food for providing nutrition and eliminating toxins from human cells; however, its functional ingredients have also played an important role in health benefits. Flavonoids, saponarin, lutonarin, K, Ca, Se, dietary fiber, polysaccharide, alkaloid, glycoside, tannin, metallothionein and polyphenols are all found in barley grass. Microscopical studies showed that stomata, epidermal cells and trichomes were conducted as part of a pharmacognostic investigation of the grass of H. vulgare. The qualitative assays were done to predict the presence of phenols, tannin and flavonoid content. The Minimum inhibitory concentration (MIC) method was used to screen H. vulgare leaf extract for antimicrobial potential against S. typhi, S. aureus, B. subtilis and E. coli and chloramphenicol was used as a standard. Amongst all the extracts, the chloroform extract of H. vulgare was found to be more effective as its MIC value is almost equal to the standard antibiotic...
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Posted by admin on Jun 30, 2023 in |
Antibiotic yield has been raised by numerous pharmaceutical firms in response to the rising population, the COVID-19 outbreak, and the introduction of several new diseases. Several heavy metals are used in the antibiotics’ formulation. The release of antibiotics and heavy metal ions has wreaked havoc on the ecosystem. The issue with heavy metals is that the bulk of them last a long time in the environment and are a leading cause of different types of cancer and other human diseases. On the other hand, experts worldwide are concerned about the presence of antibiotics in the environment, particularly in wastewater, because it leads to the emergence of antibiotic-resistant microorganisms (superbugs) that can cause widespread damage. Bioremediation is a viable approach for treating pharmaceutical industry wastewater with antibiotics and heavy metal ions. Copper, cadmium, nickel, zinc, lead and iron are common heavy metal ions found in wastewater from antibiotic-producing pharmaceutical firms. Along with it, antibiotics like chlortetracycline, oxytetracycline, cefalexin, Sulfamethoxazole, norfloxacin and ciprofloxacin are frequently found in the effluent of pharmaceutical...
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Posted by admin on Jun 30, 2023 in |
Introduction: The aim was this trial is to assess to evaluate the effect of “Chaturjatadi Sambharaka” in the management of malnutrition in Children. Material and methods: This research work was done in two phases. Phase one included demographic study and in phase two was clinical study. A Randomized open label-controlled trial was conducted on100 undernourished children of 1-10 years of age group. Total cases were divided into two groups (50 in each). In Group A, only Nutritional Rehabilitation (As per ICMR guidelines) was administered whereas in Group B, Nutritional Rehabilitation (As per ICMR guidelines) along with the trial drug Chaturjatadi Sambharaka was administered. The trial drug was administered in Avleha form in a dose 180-200 mg/kg/day in divided dose or 8 weeks and post follow up was done after month. Scoring of chief clinical features was done before and after treatment. Result: The clinical efficacy of the drug was analysed statistically on all parameters mentioned in the Assessment criteria. Both groups, showed statistically significant (P<0.001) improvement on anthropometric parameters-...
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