Posted by admin on Jun 30, 2023 in |
Despite the considerable advancement in medical sciences and allopathic medicines, the use of complementary and alternative medicines has dramatically increased worldwide. Bacopa monnieri is one of the most important and highly studied medicinal plants that is being used as an ayurvedic or ethnomedicine for thousands of years. It improves intelligence rejuvenation and treats mental illness, fever, a blood disorder, anemia, etc. The main phytoconstituents of B. monnieri have been reported as alkaloids, saponins, flavonoids, and glycosides, including various sterols and potassium salts. The plant possesses multiple pharmacological properties, such as memory enhancer, anti-depressant, anti-inflammatory, antioxidant, gastroprotective, anxiolytic, hepato-protective, anti-cancer, anti-hyperglycemic, antimicrobial, etc. The pharmacological properties of the plant can be attributed to the presence of saponin-bacoside. The formulations of this plant are used for clinical applications by numerous research groups and pharmaceutical companies worldwide, including in Asia, Australia, and the United States of America. Considering the importance of the plant, the present review summarizes the ethnomedicinal and pharmacological activities of B. monnieri, which may help in exploring the untapped...
Read More
Posted by admin on Jun 30, 2023 in |
Understanding the preponderance of respiratory conditions with the symptoms like sore throat and cough being even more common, owing to the coronavirus outbreak. The improved resolution method was developed to quantify drugs Loratidine and Ambroxol from the most effective dosage regimen to treat sore throat and cough. An accurate, precise method was developed for concurrently estimating drugs from combined tablet dosage form by first-order derivative UV spectrophotometric method. Absorption maxima were determined as 265 nm for Ambroxol hydrochloride (ZCP for Loratadine) and 307 nm for Loratadine (ZCP for ambroxol hydrochloride), using 0.1 N HCl as a solvent for estimation. The analysis results were developed as per ICH guidelines and the drugs obeyed beer lambert’s law in a concentration range of 10 – 125 µg/mL for Ambroxol hydrochloride and 2 – 12 µg/mL for Loratadine with a regression coefficient of 0.9994 and 0.999 respectively. The %RSD values (<2) in precision studies indicate the method’s reproducibility. The LOD values were found to be 1.35µg/ml and 0.37µg/mL, and LOQ values were found...
Read More
Posted by admin on Jun 30, 2023 in |
Ophthalmic drug delivery is greatly onerous for a better remedial response in any type of disease state for instance, conjunctivitis, more commonly published as pinkeye, is an inflammation of the conjunctiva, a clear membrane that envelopes the outmost lamina of the eye and the inside surface of the eyelids. Usually, conjunctivitis is of the following classes depending on their origins of contagion as like (Allergic conjunctivitis, viral conjunctivitis, Bacterial conjunctivitis, and Irritant and Chemical conjunctivitis). It possibly will cause a number of symptoms grounded on their causative reason, for example Itchiness, body aches, sensitiveness to light, uneasiness in the eye, redness of the eye or inward eyelids, discharge as well as tearness. Discharge may give rise to eyelids crusting and stick together while sleeping and swelling of the...
Read More
Posted by admin on Jun 30, 2023 in |
Background: Vitamin D is a lipid-soluble vitamin that plays an important role in maintaining calcium and phosphorus homeostasis and promoting bone metabolism. It sustains normal values of calcium and phosphorus in the systemic circulation. If the exogenous calcium sources are insufficient, vitamin D together with the parathyroid hormone (PTH) will direct part of the bone calcium. Circulating serum 1, 25(OH)2 D gradually increases during the 1st and 2nd trimesters, owing to an increase in Vitamin D-binding protein concentrations in the maternal circulation. However, it is the free levels of 1, 25(OH)2 D, which are actually responsible for enhancing transport of calcium across the placenta. Hormonal changes initiated even before conception significantly alter maternal biochemistry early in pregnancy. Steroid hormones, peptide hormones and prostaglandins interact to expand blood and plasma volume and modulate the maternal capacity to supply energy and nutrients to the fetoplacental...
Read More
Posted by admin on Jun 30, 2023 in |
This entire study is based on the drug delivery system of the pharmaceutical company to design the drugs. In order to identify the effectiveness of the drug, this study has tried to identify the bonds between peptides & proteins. In this context, this study has chosen the drug acetazolamide and based on the chemical properties, it has made a calibration curve of the drugs in water solution. In addition, this study has tried to analyze the recompression factors to identify the percentages of drug release in relevant time...
Read More
