Posted by admin on Jul 31, 2024 in |
In obese patients with noninsulin-dependent diabetes mellitus (NIDDM), reducing calorie intake improves glycemic control. The present study tested the theory that controlling calorie intake has an important role in long term, independent of weight loss in metabolic regulation of NIDDM patients. 23 women included in this study were selected, Antidiabetic therapy (except metformin) was discontinued concurrently with the start of VLCKD diet and Parameters were collected at starting program and once every 3 months for a year. In result, on T3 (after 9 months) ofVLCKD restriction produced substantial decreases in fasting plasma glucose for (19±9.31 ), HbA1c % (1±0.34),Weight loss (35.6±9.9), BMI (11.9±2.5 ), Tri Acyl Glycerol(22.99±19.27) and Total Cholesterol (52.5±4.89), and no significant decreasing in Creatinine is found .While on T4 ( after 12 months)there is a significant decreasing in: fasting plasma glucose for (18±8.41 ), HbA1c % (1±0.5), Weight loss (33.5±10.3), BMI (12.3±2.2 ), Tri Acyl Glycerol (18±22.1) and Total Cholesterol (46.7±21.5), and no significant decreasing in Creatinine. It is important to noticethe stability of biochemical parameters...
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Posted by admin on Jul 31, 2024 in |
Clitoria ternatea (Blue tea) is a traditional medicinal plant belonging to family Fabaceae having generous amount of anthocyanins which possess majorly antioxidant properties. It contains wide range of phytoconstituents such as triterpenoids, flavanol glycosides, tannins, alkaloids, amino acids, proteins, ternatins (poly acylated anthocyanins) and carbohydrates etc. According to the data obtained from different in-vitro studies, this plant possess antioxidant, antimicrobial, antidiabetic, hepatoprotective, nootropic, central cholinergic, antidepressant, antianxiety, anticonvulsant, anti-inflammatory, analgesic, antipyretic, wound healing, anticancer and many other pharmacological properties. In this report various preclinical studies data revealed about the efficacy of Clitoria ternatea plant in the treatment of neurological, inflammatory and oxidative stress induced...
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Posted by admin on Jul 31, 2024 in |
Biochar can be used as an efficient and low-cost adsorbent for wastewater treatment as heavy metal pollution has become the serious issue for environmental pollution today. A number of studies have demonstrated effective removal of heavy metals from water by biochar. Several factors affecting the sorption tendency of biochar, feedstocks materials play a significant role. Depending on the biochar type, heavy metals can be removed by different methods such as complexation, physical sorption, precipitation and electrostatic interactions. In recent years, ample method for heavy metal removal from wastewater has been extensively studied. This paper reviews the recent methods that have been used to treat heavy metal removal from wastewater and evaluates these techniques. These techniques include ion-exchange capacity, adsorption, membrane filtration, coagulation-flocculation, flotation and electrochemical methods. From literature review it is evident that ion-exchange, adsorption and membrane filtration are the most recent studied for the treatment of heavy metal...
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Posted by admin on Jul 31, 2024 in |
Diabetes is a chronic disease characterized by fasting blood glucose levels above 1.26 g/L. The aim of the present study was to evaluate the effect of the methanolic extract of Picralima nitida seeds on insulin and blood glucose levels in diabetic rats. Diabetes was induced in normoglycemic rats by injection of 1 mL alloxane at a dose of 125 mg/kg bw for three consecutive days. Blood samples were taken every other day to determine insulin and blood glucose levels. Diabetic rats were then treated for 14 days with 10, 20 and 50 mg/kg bw of P. nitida seed extract and 5 mg/kg bw of Glibenclamide®. At the end of treatment, the rats’ blood was collected again for determination of insulin and blood glucose P. nitida levels. The results obtained show that initial insulinemia, which was 16 ± 0.12 μU/mL, fell in diabetic rats (7 ± 0.004 μU/mL) before significantly increasing to 15 ± 0.3 μU/mL and 17 μU/mL ± 0.02 after treatment with P. nitida extract and Glibenclamide®. In...
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Posted by admin on Jul 31, 2024 in |
Objectives: Grewia hirsuta Vahl. is a shrub explored for medicinal applications. It has anti ageing, boosting immunity, prevents loss and grey hair etc. Ethnopharmacological data suggests that the plant is extensively used as a nerve tonic and to enhance the cognitive properties. The basis of these medicinal uses seems to be antioxidant and anti cholinesterase activity. In order to establish the scientific basis between medicinal uses and its mechanism of action, antioxidant and anti cholinesterase activity investigations were carried out. Methods: Evaluation of free radical scavenging and anti cholinesterase activity was carried out using DPPH (1, 1- diphenyl-2-picryl hydrazyl), hydroxyl radical scavenging and ferric reducing method using ascorbic acid as a standard. Cholinesterase inhibitory potentials were measured by Ellman’s method against Rivastigmine. Results: The inhibitory concentration of hydro ethanolic extract of Grewia hirsuta (HEEGH) (IC50 27.25) in DPPH. In reducing power assay (IC50 65.32) and Hydrogen peroxide scavenging activity (IC50 98.28). The inhibitor concentration of acetylcholinesterase by standard (Rivastigmine) was (IC50 14.40μg/ml), and the extract was (IC50 133.4μg/ml), whereas,...
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