Posted by admin on May 31, 2024 in |
Livamurtha, traditional polyherbal formulation possess hepato-protective, antibacterial, and antihepatotoxic properties used for treating liver disorders. This exploratory study was designed to evaluate the acute and sub acute toxicity effects of traditional formulation in albino mice based on the OECD Guidelines. 10g of formulation ”Livamurtha” was boiled in 500ml of water for 1 hour. The decocation (Filtrate) obtained was evaporated and later were reconstituted in water for further analysis. In acute toxicity study, healthy albino mice were chosen for study with starting single dose of 5mg/kg/body weight followed by single doses of 50,300 and 2000mg/Kg/body weight in separate group of each 3 animals. The animals were observed for 14 days and its physical activities were noted. In sub toxicity study, the aqueous extract of formulation was administered orally at repeated dose of 300 and 600 mg/kg body weight for 28 days. The animals were sacrificed on the 29th day for further haematological, biochemical and histopathological examinations were done. In acute toxicity, no behavioural changes, mortality and toxicity was observed in...
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Posted by admin on May 31, 2024 in |
Psychopathy is associate rising health issue in current times. In recent years, there has been increasing acknowledgement of mental state that plays a very important role in achieving international development goals. Several health conditions will be effectively treated at comparatively low price, however the gap between individuals needing care and people with access to worry stay substantial. This analysis has been conducted to work out the angle of pharmacy professionals towards psychopathy and insane persons (mentally ill) by mistreatment the BMI (Beliefs towards Mental Illness) scale. The BMI scale was designed to live such beliefs also on predict the requirement of study regarding mental state and health problem. The percentage of each subscale which shows the significant knowledge towards mentally ill persons and their treatment seeking behavior is based on the assumption of higher obtainable score of the total participants. The percentages of the subscale were found. Dangerousness = 51.59%. Poor social and interpersonal skill = 43.22%. Incurability = 49.81%. The negative beliefs/notions towards mentally ill people were found...
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Posted by admin on May 31, 2024 in |
The objective was to determine the effect of calcium phosphate composite with doxycycline molecularly included as a graft on bone defect after tooth extraction for slow delivery of drug. Methods: animal were distributed in to four groups: Group 1 (Blood Clot), Group 2 (TCP), Group 3 (TCP/PCL/PLGA), and Group 4 (TCP/PCL/ PLGA/ DOX/CD). An alveolar bone defect was created, and the analysis was conducted at preset intervals of T1 (14 days) and T2 (28 days). Results: The results of the histological study using H&E staining demonstrated the existence of newly created bone in all experimental groups. Group 4 exhibited the biggest area of newly formed bone at T1, and this observation was consistent across all time points examined. Group 4 exhibited a consistent volume across the measured time intervals, as evidenced by the existence of more advanced and structured trabeculated bone in T2 in comparison to T1. Even more Group 4, notably T2, displayed the highest proportion (47%) of newly formed bone area in comparison to Group 1 (36%),...
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Posted by admin on May 31, 2024 in |
The term nutrabeverage was applied to the product of alcoholic fermentation made by using Kefir grains. In the present studies initially, the pH of the pomegranate juice sample was 3.7, 3.5 for strawberry and 3.8 pH for pineapple. The titrable acidity optimum was found in pineapple at 3.37 % while 16% TSS was found in pomegranate. The highest TSS content before fermentation was observed at 160brix, 90brix and 14.30 brix in the pomegranate, strawberry and pineapple juice respectively. After 15 days of fermentation at 25°C with pH 4.5, the lowest TSS content of 120brix, 8.30brix, and 100brix in the pomegranate, strawberry and pineapple nutrabeverage was observed respectively. The titrable acidity was found to increase after 15 days of fermentation at 25°C in all nutrabeverage while reducing sugar was found to the maximum before fermentation. The lowest reducing sugar content was 9.73%, 6.81% and 8.82% in the pomegranate, strawberry and pineapple nutrabeverage respectively recorded after fermentation. The maximum alcohol content 6.9%, 4.3% and 5.2% in the pomegranate, strawberry and pineapple...
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Posted by admin on May 31, 2024 in |
Phytosterols, a subclass of steroids, have gained considerable attention in scientific research and nutrition due to their potential health benefits. This article presents an overview of phytosterols, encompassing their sources, chemistry, extraction methods, analytical techniques, and biological activities. Phytosterols, structurally resembling cholesterol, are found abundantly in plants, animals, and fungi. Their physiological roles include influencing membrane fluidity and acting as second messengers in signal transduction pathways. Incorporating phytosterol-rich foods into the diet has been linked to various health benefits, particularly in reducing cholesterol levels, as recognized by regulatory bodies like the European Food Safety Authority and the FDA. The article discusses various extraction methods for phytosterols, emphasizing the need for environmentally friendly approaches to minimize the use of organic solvents. Traditional techniques such as Soxhlet extraction are effective but pose health and environmental concerns, driving the exploration of alternative extraction technologies. Phytosterol chemistry, characterized by specific carbon atoms and side chains, is explored, highlighting their steroid structure and different forms in nature. Analytical methods such as gas chromatography (GC),...
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