Posted by admin on May 31, 2024 in |
Artificial sweeteners are non-nutritive sugar substitutes designed to provide sweetness without the calorie content of sugar. Examples like Saccharin, Aspartame, Neotame Acesulfame K and they are used in producing a low- or no-calorie diet to lose weight. In the last few years, they have be used in most of the products. Now a days artificial sweeteners are used because they have no calories and pose no risk of obesity. It provides the detailed description of some of the artificial sweeteners and their history, uses and adverse effects. They are often used in food and beverages as alternatives to sugar, providing individuals pursuing to reduce their sugar intake. The artificial sweeteners have an important impact on people who have diabetes or overweight. Validation was performed to know the Linearity, Precision, Ruggedness, Robustness, Limit of detection, Limit of quantification. A simple method is used to determine the artificial sweeteners like saccharin and Aspartame based on UV visible spectrophotometric method and this article provides the analysis of Saccharin and Aspartame and including...
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Posted by admin on May 31, 2024 in |
Mucoadhesive buccal films have gained significant attention as a promising drug delivery system for various therapeutic applications. This review article provides a comprehensive overview of the recent advancements in mucoadhesive buccal films, focusing on their formulation strategies, mucoadhesive mechanisms and potential applications. The article discusses the various polymers used in the formulation of mucoadhesive buccal films, including natural, synthetic, and semi-synthetic polymers. The selection of appropriate polymers plays a crucial role in achieving optimal mucoadhesive properties and drug release characteristics. Furthermore, the influence of different formulation factors, such as plasticizers, penetration enhancers, and drug loading techniques, on the performance of buccal films is thoroughly examined. The discussion covers a wide range of topics, beginning with the structure and physiology of the buccal mucosa, which elucidates the particular properties that impact medication absorption. The complete examination of mucoadhesive polymers, nanoparticles, and thin film technologies is included in the comprehensive overview of formulation...
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Posted by admin on May 31, 2024 in |
Introduction: The increasing trends for caesarean section (CS) not only in India but also globally have been a cause of concern. With the aim of comparing and analyzing CS rates worldwide, the WHO suggests Robson’s ten group classification system (RTGCS). Aims and Objectives: To find the groups of women with high CS rate which will help policymakers to target that specific groups of women for the reduction of overall CS. Materials and Methods: This was a retrospective study design using hospital records for women delivered between January 1, 2021 and December 31, 2021. Data were entered and analyzed using Excel and presented in percentages after using RTGCS. Results: Out of total 12645 women delivered during the study period, 7180(56.78%) were delivered by CS. The high CS rates were in group 9 (abnormal lie) – 100%, group 6 (breech nulliparous) -94.73%, group 5 (previous CS) -93.67%. In respect of all CS, the maximum contribution was done by group 5 (31.03%), group 1 (23.90%) and group 10 (20.55%). Conclusions: The result...
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Posted by admin on May 31, 2024 in |
The most prevalent condition affecting the nails is onychomycosis. It is a typical nail fungal infection that causes millions of individuals globally. Yeasts, non-dermatophyte moulds, and dermatophytes can all be the cause. It’s not only results in physical discomfort but also has a major negative effect on the affected person’s quality of life. This infection affects the nails of the toes and fingers, causing discoloration, thickness, and brittleness of the nails. While the condition is not life threating, but it can be uncomfortable and unsightly, leading many patients to seek treatment. Previously these treatments ranged from oral medication to topical ointments and laser therapy, each with its benefits and drawbacks Fortunately, recent improvements in onychomycosis diagnosis and treatment have provided new hope for patients. It will deal with the recent treatment available and the novel treatment which can be developed. In this comprehensive review, we will explore the latest research and developments in the field, discussing novel treatment modalities, diagnostic techniques, and safety considerations. Additionally, new techniques include photodynamic...
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Posted by admin on May 31, 2024 in |
Varicose vein is a clinical class of Chronic Venous Disease also called the varicosites. Varicose veins are enlarged, swollen and twisting veins often appearing blue or dark purple. It is more common in women than men, superficial veins of the leg are under high pressure, hence this disorder is mostly seen in the leg. The pathophysiology includes genetic components, dysfunctional valves, and weak vascular walls. In order for conservative treatments like diet, dietary, and hydrotherapy to be effective, a high level of patient compliance is needed. Interventional therapies like surgery are also used to treat varicose veins. Although varicose veins are not considered an imminent threat to life, they may interfere with regular activities and develop gradually. As a result, the current review critically assesses the possible utility of herbal medication in the treatment of varicose...
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