Posted by admin on Nov 30, 2017 in |
India is a focus for development of Ayurveda, Unani, Siddha, Homoeopathy and another natural herbs based health science (AYUSH). Ayush Pharmaceutical industry having great possible and contingency for saundarya prasadka category (herbal cosmetic) development in future. Natural beauty is blessing and cosmetics help in presenting and increaning the beauty and personality aspects of human beings. Saundarya prasadak are the preparation, which represent cosmetic base correlate with known Ayurveda, Siddha and Unani (ASU) drugs active ingredient (which reference are readily available in schedule 1st book of Drug and cosmetic act 1940 and rule 1945). In traditional era people were used to various lepa, Alepa, Pralepa, Udavartan, Prakshalan etc for saundrya prasadan karma. Nature has offered the way to keep up that parity. Herbs! Yes herbs are one such means. An herb is a plant or plant extract, including leaves, bark, berries, roots, gums, seeds, stems and flowers which are favour with nourishing and healing elements. Cosmetics alone are not competent to take care of skin and others body parts, it...
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Posted by admin on Nov 30, 2017 in |
The aim of this review is to assess the efficacy of treatments for postmenopausal osteoporosis in women with low bone mass or with an existing vertebral fracture. Osteoporosis is a worldwide health problem related to the aging of the population, and it is often under diagnosed and undertreated. It is related to substantial morbidity, mortality and impairment of the quality of life. Estrogen deficiency is the major contributing factor to bone loss after menopause. Postmenopausal osteoporosis is a silent disease in most cases, with no symptoms until fractures occur. It is characterized by low bone mineral density (BMD) and changes in bone micro architecture that reduce bone strength and increase fracture risk. The objective of this study was to present a systematic review of drugs for treatment of osteoporosis, focusing on the adequacy of clinical protocols based on existing evidence in the scientific literature. So, our study recommends that postmenopausal women should be screened for osteoporotic fracture risk which may be important strategy in the management of postmenopausal...
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Posted by admin on Nov 30, 2017 in |
The objective of present study was to investigate optimized nefopam hydrochloride loaded microspheres (NPH-MS) by investigating the relationship between independent and dependent variables using response surface methodology. Central composite design with thirty three batches was constructed using drug: polymer (X1), PHB: PCL (X2), stirring speed (X3), stirring time (X4) and polyvinyl alcohol (PVA) (X5) level as independent factors. NPH-MS were manufactured using polyhydroxybutyrate (PHB) and poly ε-caprolactone (PCL) by double emulsion solvent evaporation technique. The response variables were % entrapment efficiency (Y1), mean diameter (Y2), % drug loading (Y3), and % yield (Y4). Second-order polynomial equations for (Y1-Y4) were developed by Design-expert® 9.0.5.1 software. Positive and negative signs of regression coefficient indicated synergistic and antagonistic effect on response variables, respectively. Optimized NPH-MS estimated by design-expert software have highest desirability function, D = 0.911 and X1, X2, X3, X4 and X5 were 1: 2.86, 1:1.19, 1501 rpm, 2.98 h and 0.54 % w/v, respectively. The model predicted values of Y1, Y2, Y3 and Y4 for optimized NPH-MS were 83.80%, 100.78μm,...
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Posted by admin on Nov 30, 2017 in |
Elaeocarpus ganitrus Roxb is widely used in traditional medicine to cure various diseases. In this present study, the phytochemical constituents, antioxidant activity and inhibitory effect on alpha amylase by the ethanolic extracts of the Elaeocarpus ganitrus (bark) were investigated. The dried bark of Elaeocarpus ganitrus was extracted by using ethanol as a solvent for extraction with the help of Soxhlet apparatus. The solvent free crude was screened for presence of phytochemicals, antioxidant activity and alpha amylase inhibitory effect. The screening for phytochemicals showed the presence of carbohydrates, alkaloids, steroids, flavonoids, phenol, tannin, Saponin, glycosides and terpenoids. The ethanolic extract showed a concentration dependent increase in antioxidant activity (Upto 79% by DPPH method and upto 72.8% by H2O2 method), which can be used as a potential anti-aging agent and in the treatmentof free radical associated diseases. The ethanolic extract also showed a dose dependent increase in inhibitory effect on alpha amylase (Upto 82%) which can be used as a potential source as antidiabetic drug. From the current study it can...
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Posted by admin on Nov 30, 2017 in |
Allergic Rhinitis (AR) represents a common and serious health problem in pediatric age group in term of outpatient visit. The chronic nature of disease and its association with other comorbid conditions like asthma, eczema etc. has shown significant negative impact on quality of life, school performance and cognitive functioning in children which has influenced many parents to seek alternative therapies. Moreover there is a growing concern of long term use of dose related side effects of corticosteroids, antihistaminic etc. Considering etiopatho genesis of AR, Ayurvedic herbal drugs possessing properties of antihistaminic, mast cell stabilizer and immunomodulators, alone or in combination can show positive effects in relieving the symptoms of AR. Thus in this review paper, an attempt has been made in this direction to prepare a comprehensive list of herbal drugs with above aforementioned properties that can help in the management of AR in pediatric age group with better clinical efficacy and safety...
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