α-GLUCOSIDASE AND α -AMYLASE INHIBITORY ACTIVITIES OF RAPHANUS SATIVUS LINN.
AbstractHerbal medicine has been used for many years by different cultures around the world for the treatment of diabetes. There has been an enormous interest in the development of alternative medicines for type 2 diabetes, specifically screening for phytochemicals with the ability to delay or prevent glucose absorption. The goal of the present study is to evaluate the invitro antidiabetic activity of Raphanus sativus ethanolic extract and fractions by α-glucosidase and α -amylase inhibitory activity. Raphanus sativusethanolic extract and fractions showed dose dependent inhibition of α-glucosidase and α -amylase enzyme and exhibited lower inhibitory activity than acarbose. The study revealed the antidiabetic potential and could be helpful to develop medicinal preparations and nutraceuticals and function foods for diabetes
Article Information
35
3186-3188
619KB
1633
English
IJPSR
Ramachandran Vadivelan*, Sanagai Palaniswami Dhanabal , Ashish Wadhawani and Kannan Elango
Assistant Professor, Department of Pharmacology, JSS College of Pharmacy, (Off Campus of JSS University, Mysore), Ooty, Nilgiris-643001, Karnataka, India
rv_sofia@rediffmail.com
09 May, 2012
14 June, 2012
20 August, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3186-88
01 September, 2012
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