A BRIEF INSIGHT INTO THE PHARMACOTHERAPY OF OBESITY, DRUGS WITHDRAWN, DRUGS IN MARKET AND IN PIPELINE: A REVIEW
AbstractA Multifactorial disorder primarily of energy balance, which occurs due to imbalance between energy expenditure and excess of calorie intake. Obesity is becoming a serious health related problem worldwide. Appropriate Treatment plans as well as Goals have been established for this disorder, when a patient presents with certain complications, for example, type-2 diabetes mellitus, cardiovascular disease presents with obesity. A number of medications have been approved by the U S Food and Drug Administration for the treatment of this disorder. However, the medications should be used in conjunction with healthy eating habits and physical activity. Several medications have been withdrawn due to serious adverse effects, yet several new drugs are in trials. This article will review the Pathophysiology of the occurrence of obesity, the neurotransmitters involved in its onset, the history of medications: why and which were withdrawn, what all medications are available, what are the future for the treatment of patients suffering from obesity.
Article Information
8
1558-1565
615 KB
62
English
IJPSR
Amanjot Kaur * and Jasninder Singh
Department of Pharmacology, Adesh Institute of Medical Sciences and Research, Bathinda, Punjab, India.
amanghuman66@gmail.com
22 December 2024
07 January 2025
09 January 2025
10.13040/IJPSR.0975-8232.16(6).1558-65
01 June 2025